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Cholesterol Reduction

References

Arruzazabala, M.L. et al.. Comparative study of policosanol, aspirin and the combination therapy policosanol-aspirin on platelet aggregation in healthy volunteers. Pharmacol. Res. 1997; 36:293-7.

Stusser, R. et al. Long-term therapy with policosanol improves treadmill exercise-ECG testing performance of coronary heart disease patients. Int. J. Clin. Pharmacol. Ther. 1998; 36:469-73.

Carbajal, D. et al. Effect of policosanol on platelet aggregation and serum levels of arachidonic acid metabolites in healthy volunteers. Prost. Leuk. Essen. Fatty Acids 1998; 58:61-4.

Lindstedt, L. et al. Matrix metalloproteinases-3, -7, and -12, but not -9, reduce high density lipoprotein-induced cholesterol efflux from human macrophage foam cells by truncation of carboxyl terminus of apolipoprotein A-I. Parallel losses of pre-beta particles and the high affinity component of efflux. J. Biol. Chem. 1999; 274:22627-34.

Mas, R. et al. Effects of policosanol in patients with type II hypercholetserolemia and additional coronary risk factors. Clin. Pharmacol. Ther. 1999; 65:439-47.

Menendez, R. et al. Oral administration of policosanol inhibits in vitro copper ion-induced rat lipoprotein peroxidation. Physiol. Behav. 1999; 67:1-7.

Negre-Aminou, P. et al. Antiproliferative potencies of 6 vastatins in cultured human cells: involvement of the ras-mediated signalling pathway. Presented at the 66th Congress of the European Atherosclerosis Society 1996; July 13-17, Florence): 120.

Noa, M. et al. Effect of policosanol on lipofundin-induced atherosclerotic lesions in rats. J. Pharm. Pharmacol. 1995; 47:289-91.

Noa, M. et al. Effect of policosanol on foam-cell formation in carrageenan-induced granulomas in rats. J. Pharm. Pharmacol. 1996; 48:282-5.

Noa, M. et al. Effect of olicosanol on damaged arterial wall induced by forceps in rabbits. J. Electron. Microsc. 1998; 4:629-30.

Xu, X.P. et al. Oxidized low-density lipoprotein regulates matrix metalloproteinase-9 and its tissue inhibitor in human monocyte-derive macrophages. Circulation 1999; 99:993-8.

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