Life Extension is a global authority on nutrition, health and wellness

Folic acid (folate) is a member of the B-complex family. It is found in abundance in leafy green vegetables, but is often deficient in the standard American diet. Folic acid participates in a coenzyme reaction that synthesizes DNA needed for cell growth and new cell formation, and helps convert vitamin B12 to one of its coenzyme forms.135-137

Folic acid provides the following health benefits:

• Helps promote healthy DNA function138
• Maintains already normal homocysteine levels,
which is important for heart health139-142
• Participates in the utilization of sugar and carbohydrates143
• Promotes healthier skin135
• Helps maintain a healthy GI tract144
• Maintains healthy endothelial function145
• Improves mild memory problems associated with aging146

A deficiency of folate can result in impaired cell division and protein synthesis. With diminished replacement of healthy red blood cells and intestinal cells, a decline in GI tract function can ensue. The systemic need for folate increases in certain states in which increased cell multiplication is needed. Chronic use of medications such as aspirin and antacids can interfere with the natural synthesis of folate.147

Healthful diets with adequate folate may reduce a woman’s risk of having a child with a brain or spinal cord defect. Women of childbearing age should consume 800 mcg of folate daily. Folate intake should not exceed 250% of the DV (1,000 mcg.)

Since folic acid can mask the most obvious effect of a vitamin B12 deficiency, the Life Extension Foundation Buyers Club offers only folic acid capsules that contain vitamin B12, and those taking folic acid powder are advised to add vitamin B12 powder to their daily folic acid supplement.