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DHEA (dehydroepiandrosterone)

25 mg 100 dissolve in mouth tablets, Item# 00607

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DHEA
25 mg 100 dissolve in mouth tablets
Item Catalog Number:
00607

It has been shown that the serum hormone DHEA often declines by 75%–80% from peak levels by age 70, leading to hormonal imbalances that can affect one’s quality of life.1-4 Peak blood levels of DHEA occur at approximately age 25, decreasing progressively thereafter.3 The marked decline in serum DHEA with age is believed to play a role in health problems associated with aging. Thus, scientists have been looking at ways of restoring DHEA to youthful levels to prevent or reverse those health issues, and are now discovering mechanisms by which DHEA protects against age-related decline.

Since 1981, several thousand studies have been published on DHEA’s various benefits, including immunomodulatory properties as well as positive effects on mood, quality of life, and body composition. It has been proposed that restoring the circulating levels of DHEA to those found in young people may improve well-being and sexual function. In a randomized, double-blind, placebo-controlled study, ten months of DHEA replacement therapy showed a beneficial effect of enhancing the increases in muscle mass and strength with the addition of resistance exercise in elderly individuals.4 The studies of DHEA therapy in women with adrenal insufficiency also suggest beneficial effects on well-being, mood, and sexuality.5 DHEA could be of benefit to the normal aging brain.6-8 Some studies have reported DHEA may improve mood and alleviate melancholy.9 In addition, recent studies have shown that DHEA has the capacity to improve vascular health by a number of complex processes.10-12 One of them is increasing nitric oxide synthesis.10

In a randomized, double-blind, controlled trial, DHEA replacement therapy for one year helped protect hip bone mineral density in older adults and spine bone mineral density in older women.13 DHEA has also been shown to support a healthy circulatory system and joint/bone health.10-12,14,15

DHEA usage and safety precautions

Life Extension has been investigating DHEA for over 30 years. Life Extension’s DHEA directions for use are specially drafted to provide optimal, but safe dosing.

The standard blood test to evaluate DHEA status is one that measures DHEA sulfate levels (dehydroepiandrosterone sulfate or DHEA-S). The DHEA-S is calculated in micrograms per deciliter (µg/dL) of blood. A DHEA-S blood test may be taken three to six weeks after initiating a DHEA supplementation regimen to help determine optimal dosing. DHEA testing may save you money if it shows you can take less DHEA to maintain youthful DHEA serum levels.

Because of the overwhelming evidence connecting low levels of DHEA to problems associated with aging, Life Extension suggests that all people over age 40 begin DHEA therapy. For most people, the starting dose of DHEA is between 15–75 mg, taken in one daily dose. Many studies have used a daily dose of 50 mg.

Since almost everyone over age 35–40 has lower than optimal levels of DHEA, most people begin supplementation ... and then test their blood DHEA levels later to make sure they are taking the proper dose. Normal serum reference ranges and ideal ranges of DHEA-S are:

Normal
(depending on age)
Ideal
Men
16.2-492 µg/dL
350-500 µg/dL
Women
12-407 µg/dL
275-400 µg/dL

People over age 40 who do not supplement with DHEA usually have serum levels below 200 µg/dL, and many are below 100 µg/dL since a steady decline takes place after the third decade in life.1,16

There are different precautions for men and women that should be observed.

DHEA precautions for men

Before attempting to restore DHEA to youthful levels, men should know their serum PSA (prostate specific antigen) level. Men with prostate cancer or severe benign prostate disease are advised to avoid DHEA since it can be converted into testosterone (and estrogen). Therefore, men are advised to have a PSA and digital rectal exam before initiating DHEA to rule out existing prostate disease.

When taking DHEA we also recommend taking the following other nutrients daily:

Vitamin D 5,000 – 10,000 IU
Vitamin E
(D-alpha tocopheryl succinate)
400 IU
Selenium 200 mcg
Gamma E Tocopherol
with Sesame Lignans
200 mg
Lycopene Extract 10 – 40 mg
Boron 3 – 10 mg
Cruciferous Vegetable Extracts
(as found in Triple Action Cruciferous Vegetable Extract)
500 – 1000 mg

It is important for men over 40 to have a physician check their PSA and DHEA-S serum levels every six to twelve months thereafter. Men should also periodically check their blood levels for free testosterone and estrogen to make sure that DHEA is following a youthful metabolic pathway.

See the Male Hormone Restoration protocol or the Male Hormone Modulation chapter in the Disease Prevention & Treatment book for additional hormone balance testing that can be done at the same time serum DHEA-S and PSA levels are being tested.

DHEA precautions for women

Women should consider estrogen and testosterone testing when they take their DHEA blood test in order to evaluate DHEA’s effect on their blood levels of these hormones.

Women who have been diagnosed with an estrogen-dependent cancer should consult their physicians before beginning the DHEA restoration process.

When taking DHEA we also recommend taking the following other nutrients to maintain a healthy balance each day:

Melatonin 300 mcg – 3 mg (nightly)
Vitamin E
(D-alpha tocopheryl succinate)
400 IU
Broccoli Extract
(as found in Triple Action Cruciferous Vegetable Extract)
400 mg
Indole-3-carbinol
(as found in Triple Action Cruciferous Vegetable Extract)
80 – 160 mg
Vitamin D3 5,000 – 10,000 IU
Gamma Tocopherol
with Sesame Lignans
200 mg

Women taking DHEA should refer to the Female Hormone Restoration protocol or the Female Hormone Modulation chapter in the Disease Prevention & Treatment book for information about restoring youthful hormone balance.

References
Supplement Facts

Serving Size 1 tablet

Servings Per Container 100

Amount Per Serving

Dehydroepiandrosterone (DHEA)

25 mg

Other ingredients: sorbitol, microcrystalline cellulose, croscarmellose sodium, vegetable stearate.

Dosage and Use
  • The exact number of tablets to be taken should be determined by blood testing and the advice of a physician.
  • Generally, place one to three tablets under the tongue, allow to dissolve and swallow.
  • Take in the morning and/or afternoon.
  • DHEA serum blood tests are suggested prior to and 3 to 6 weeks after initiating DHEA replacement therapy to optimize individual dosing.
  • This product can be taken with or without food.
Caution

Do not use DHEA if you are at risk for or have been diagnosed as having any type of hormonal cancer, such as prostate or breast cancer.

Warnings

REVIEW SNAPSHOT®

by PowerReviews
Life ExtensionDHEA (dehydroepiandrosterone), 25 mg 100 dissolve in mouth tablets
 
4.9

(based on 8 reviews)

Ratings Distribution

  • 5 Stars

     

    (7)

  • 4 Stars

     

    (1)

  • 3 Stars

     

    (0)

  • 2 Stars

     

    (0)

  • 1 Stars

     

    (0)

100%

of respondents would recommend this to a friend.

Pros

  • Produces results (6)
  • Simple to take (5)
  • Acts quickly (4)
  • No side effects (4)
  • Good taste (3)

Cons

    Best Uses

    • Daily use (7)
    • Men (5)
    • Older people (5)
      • Reviewer Profile:
      • Health conscious (7), Regular user (5)

    Reviewed by 8 customers

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    (1 of 1 customers found this review helpful)

     
    5.0

    I will purchase again.

    By replate

    from Denver, CO

    About Me Health Conscious, Regular User

    See all my reviews

    Pros

    • Good Taste
    • No Side Effects
    • Produces Results
    • Simple To Take

    Cons

      Best Uses

      • Daily Use
      • Men
      • Older People

      Comments about Life Extension DHEA (dehydroepiandrosterone), 25 mg 100 dissolve in mouth tablets:

      I take 3 tablets under my tongue in the morning before eating. The taste is fine and they seem to work. I found that it works with my mental well being as well as physical benefits.

      Comment on this review

      (3 of 3 customers found this review helpful)

       
      5.0

      The right dose and type for me

      By Bob G

      from Dallas, TX

      About Me Health Conscious, Regular User

      See all my reviews

      Pros

      • Creates energy

      Cons

        Best Uses

        • Daily Use
        • Older People

        Comments about Life Extension DHEA (dehydroepiandrosterone), 25 mg 100 dissolve in mouth tablets:

        This "disolve in mouth" tablet gives me subtle energy quickly and I can adjust how much I need from day to day and throughout the day. The capsule seems to do nothing but it probably does. I think this product is still not fully understood.

        Comment on this review

        (5 of 6 customers found this review helpful)

         
        4.0

        DHEA

        By A Customer

        from Pittsburgh PA

        About Me First Time User

        Pros

        • Produces Results
        • Simple To Take

        Cons

        • Causes Side Effects

        Best Uses

        • Daily Use
        • Men
        • Older People

        Comments about Life Extension DHEA (dehydroepiandrosterone), 25 mg 100 dissolve in mouth tablets:

        I have taken other forms of DHEA that I got from a compounding pharmacy with a prescription from my holistic MD, capsules and drops. I have found the Life Extension DHEA to be the most effective. It is simple to take and works, the taste is not to bad overall. One side effect of any DHEA is that it could make you skin break out. This Life Extension DHEA is no different than the other forms of DHEA I have taken in the past in that regard. Overall, I am pleased with this product and plan to continue using it.

        Comment on this review

        (4 of 4 customers found this review helpful)

         
        5.0

        Best supplement ever

        By Thriving Fellow

        from South Florida

        About Me First Time User, Health Conscious

        See all my reviews

        Pros

        • Acts Quickly
        • No Side Effects
        • Produces Results
        • Simple To Take

        Cons

          Best Uses

          • Daily Use
          • Men
          • Older People

          Comments about Life Extension DHEA (dehydroepiandrosterone), 25 mg 100 dissolve in mouth tablets:

          DHEA, is like the answer to chronic sluggishness, fatigue, etc. It increases a subtle niche of your energy, in a good way. An awesome energy spike.

          Comment on this review

          (2 of 3 customers found this review helpful)

           
          5.0

          He loves his DHEA

          By Geo. the conscious man

          from San Antonio Texas

          About Me Health Conscious, Regular User

          See all my reviews

          Pros

          • Acts Quickly
          • Good Taste
          • No Side Effects
          • Produces Results
          • Simple To Take

          Cons

            Best Uses

            • Daily Use
            • Men

            Comments about Life Extension DHEA (dehydroepiandrosterone), 25 mg 100 dissolve in mouth tablets:

            George has been taking your DHEA product for over a year .

            Very easy to take, it dissolves in your mouth with in no time.

            Comment on this review

            (3 of 3 customers found this review helpful)

             
            5.0

            High quality product in a great form

            By Organic Girl

            from Jacksonville, FL

            About Me Health Conscious, Regular User

            See all my reviews

            Verified Buyer

            Pros

            • Produces Results

            Cons

              Best Uses

              • Daily Use

              Comments about Life Extension DHEA (dehydroepiandrosterone), 25 mg 100 dissolve in mouth tablets:

              I love this DHEA product in a sublingual form since it bypasses the liver. I've used this product for years and I notice an improvement in my subjective sense of well being when I stay on it.

              Comment on this review

              (1 of 1 customers found this review helpful)

               
              5.0

              Great product. Works well for me.

              By Chad the musician

              from Wisconsin

              About Me Health Conscious, Regular User

              Pros

              • Acts Quickly
              • Good Taste
              • No Side Effects
              • Produces Results
              • Simple To Take

              Cons

                Best Uses

                • Daily Use
                • Men
                • Older People

                Comments about Life Extension DHEA (dehydroepiandrosterone), 25 mg 100 dissolve in mouth tablets:

                I use the product daily. I have managed to beat my age and remain biologically younger than my age. I feel fit and energetic and am able to do a full time job though I am a senior.

                Comment on this review

                (1 of 1 customers found this review helpful)

                 
                5.0

                good dhea form for me

                By redwing

                from Minnesota

                About Me Health Conscious

                Verified Buyer

                Pros

                • Acts Quickly

                Cons

                  Best Uses

                    Comments about Life Extension DHEA (dehydroepiandrosterone), 25 mg 100 dissolve in mouth tablets:

                    I have used this for several years with good results . It goes into the system and acts quickly.
                    I even break it in parts so I can dose through the day if I need it

                    Comment on this review

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