For nearly three decades, doctors in Germany have used a standardized extract of the herb butterbur for their patients suffering from nasal discomfort and its related problems.318-320 Butterbur’s main active ingredient is petasin, a phytochemical that may reduce spasms in smooth muscle, thus relaxing swollen nasal membranes.321
Butterbur Extract with Standardized Rosmarinic Acid contains a patented butterbur extract. State-of-the-art technology allows for standardization of butterbur’s key active ingredients while containing extremely low levels (<0.1 ppm) of Pyrrolizidine alkaloids (PA).
This formula also contains standardized rosmarinic acid, a plant polyphenol derived from rosemary leaf. Rosmarinic acid helps to regulate inflammatory responder cells while supporting healthy immune function.322-326 Luteolin, another plant flavonoid, has potent fluid-regulating properties both in vitro and in vivo. It also has been shown to help maintain normal respiratory function.327-329 Luteolin may also protect against cytokine-induced pancreatic beta-cell damage through suppression of NF-kappaB activation.330-333 Also included is perilla leaf extract. When enriched with rosmarinic acid, perilla leaf extract has been shown to provide significant seasonal support for the body.334,335