Optimized Carnitine with GlycoCarn®

A major cause of aging is a reduction in the energy-producing components of the cell, resulting in reduced cellular metabolic activity, and the accumulation of cellular debris.1-7 L-carnitine helps maintain cellular energy metabolism by assisting in the transport of fat through the cell membrane and into the mitochondria within the cell, where fats are oxidized to produce the cellular energy ATP.8-13

Acetyl-L-carnitine is the acetylated ester of the amino acid L-carnitine. Acetyl-L-carnitine is an endogenous mitochondrial membrane compound that helps maintain mitochondrial bioenergetics and lowers the increased oxidative stress associated with aging.14 Acetyl-L-carnitine and L-carnitine are absorbed into the bloodstream efficiently. Both are effective at carrying long-chain fatty acids across the membrane into the mitochondria where they are burned for energy production and utilized efficiently by the  cells.15-17 Acetyl-L-carnitine also guards against oxidative damage.18,19 Amyloid-beta peptide is a principal component of plaques and is thought to be a contributor to the aging process. Acetyl-L-carnitine exerts protective effects against such neurotoxicity and oxidative stress.14

Optimized Carnitine with GlycoCarn® combines three advanced forms of carnitine in one single formula to help you optimize energy output:

• Acetyl-L-carnitine crosses the blood-brain barrier to combat oxidative stress and promote energy production in brain and central nervous system tissues.20 It also supports the release and synthesis of acetylcholine, enhances the release of dopamine from neurons and helps it bind to dopamine receptors.
• Acetyl-L-carnitine arginate (ArginoCarn®) is a patented form of carnitine. Cell studies suggest that it promotes the growth of neurites that facilitate communication among nerve cells in the brain.21
• GlycoCarn® is a patented form of carnitine called glycine propionyl-L-carnitine that is molecularly bonded to glycine, one of the precursor amino acids to carnitine biosynthesis. This form offers such benefits as enhanced fatty acid metabolism, antioxidant activity and increased nitric oxide production. In addition, GlycoCarn® promotes optimal blood flow and combats muscle fatigue by increasing energy and sparing glycogen stores.22

These optimized forms of carnitine help transport fatty acids right to the heart of your energy-producing mitochondria. And that boost in cellular function can help you produce cellular energy faster, for a quicker recovery after exercise and less muscle fatigue during exercise.23,24 It may also benefit your brain, heart, and central nervous system right along with your muscles.

GlycoCarn® and ArginoCarn® are registered trademarks of Sigma-tau HealthScience, Inc. and are protected by Sigma-tau U.S. patent # 6,703,042 and worldwide patent EP1202956. The combination of multiple forms of Carnitine is protected by Sigma-tau patent # 6,245,378.

For some people, L-carnitine, especially acetyl-L-carnitine, may have a stimulating effect. Therefore, it may be unwise to take it in the evening.