L-arginine is a semi-essential amino acid involved in numerous areas of human biochemistry, including ammonia detoxification, hormone secretion, and immune modulation. Arginine is also well known as a precursor to nitric oxide (NO), a key component of endothelial-derived relaxing factor, an endogenous messenger molecule involved in a variety of endothelium-dependent physiological effects in the cardiovascular system.94,95
L-ornithine is a metabolite of arginine in the body, formed as a byproduct of the action of the arginase enzyme on arginine.96,97 L-arginine is required for the body to synthesize nitric oxide,98,99 which enables the arterial system to retain its youthful elasticity. Nitric oxide also helps to produce an endothelial-derived relaxing factor, which is needed by the arterial system to expand and contract with each heartbeat.100-109
L-arginine may also help maintain the health of the immune system.110-114
L-arginine is a key building block to maintaining healthy tissue and bone. L-ornithine may also be used for this purpose.115-125
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