Keep out of reach of children. Use only as directed. Not for use by diabetics, borderline diabetics, pregnant or lactating women, cancer patients, men with an enlarged prostate or with high PSA values, persons with ocular or brain herpes, or those with Wilson's Disease (a rare genetic copper metabolic disorder), Parkinson's Disease patients, or those taking anticholinergic drugs. There have been a few reports that high dietary levels of arginine may cause reactivation of latent herpes viruses in a few susceptible individuals. if this occurs, discontinue use. Those who have recently had heart attacks should not take an L-arginine-containing supplement.
Excessive consumption of choline can cause excessive muscle tone which may project symptoms such as stiff neck, muscle tension headaches, or gastric cramps. A few persons may develop a fishy smell when using a supplement containing choline due to the bacterial degradation of choline in their gut. Persons with ulcers or a history of ulcers should consult their physician before using a supplement containing choline since choline may increase stomach acid production.