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Low-Dose Vitamin K2 Menaquinone-7 (MK-7)

90 softgels, Item# 01225

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Low-Dose Vitamin K2
45 mcg 90 softgels
Item Catalog Number: 01225

An abundance of human clinical data reveals that vitamin K plays a critical role in maintaining healthy bone density by facilitating the transport of calcium from the bloodstream into the bone.6-10 Vitamin K is also required by calcium-regulating proteins in the arteries. Matrix Gla-protein (MGP) is a vitamin K-dependent protein, and it must be carboxylated to function properly. Poor vitamin K status leads to inactive uncarboxylated MGP (ucMGP), which accumulates at sites of arterial calcification.11,12 Since MGP is a potent local inhibitor of arterial calcification, MGP is important in relation to the health of the entire cardiovascular system. Without adequate vitamin K, calcium in the blood can bind to the arterial wall resulting in calcification.13,14 As people age, even a subclinical vitamin K deficiency can pose risks to the vascular system. Poor vitamin K status also results in increased circulating levels of undercarboxylated osteocalcin that is shown to be associated with increased bone loss in postmenopausal women.15,16

Vitamin K2 (menaquinones) is found in meat, eggs, and dairy products and is also made by bacteria in the human gut, which provides a certain amount of the human vitamin K requirement.20 Human studies show that vitamin K2 is up to ten times more bioavailable than K1. Vitamin K2 remains biologically active in the body far longer than K1. For instance, K1 is rapidly cleared by the liver within eight hours, whereas measurable levels of K2 (MK-7) have been detected 72 hours after ingestion.10

The Rotterdam Heart Study, a large-scale, well-controlled clinical trial that tracked 4,800 participants for seven years, revealed that participants who ingested the greatest quantities of vitamin K2 in their diet experienced a better cardiovascular condition than people who ingested the least.21 High intakes of vitamin K2 also corresponded to less calcium deposition in the aorta, whereas participants who ingested less K2 were more likely to show moderate or severe calcification. Animal studies suggest vitamin K intake not only blocks the progress of further calcium accumulation, but also induces 37% regression of preformed arterial calcification.22,23

Low-Dose Vitamin K2 contains the menaquinone-7 form of vitamin K2, which is not metabolized quickly by the liver, thereby making it available to provide a more consistent supply of vitamin K to the body.

References
Supplement Facts

Serving Size 1 softgel

Servings Per Container 90

Amount Per Serving

Vitamin K2 (as menaquinone-7)

45 mcg

Other ingredients: gelatin, medium chain triglycerides, glycerin, purified water, beeswax, olive oil, carob color.

Contains tree nuts (coconut).

Dosage and Use
  • Take one softgel daily with food, or as recommended by a healthcare practitioner.
Caution

If you are taking anti-coagulant or anti-platelet medications, or have a bleeding disorder, consult your healthcare provider before taking this product.

Warnings

REVIEW SNAPSHOT®

by PowerReviews
Life ExtensionLow-Dose Vitamin K2 Menaquinone-7 (MK-7), 90 softgels
 
4.5

(based on 4 reviews)

Ratings Distribution

  • 5 Stars

     

    (2)

  • 4 Stars

     

    (2)

  • 3 Stars

     

    (0)

  • 2 Stars

     

    (0)

  • 1 Stars

     

    (0)

100%

of respondents would recommend this to a friend.

Pros

  • Simple to take (3)

Cons

    Best Uses

    • Daily use (3)
    • Men (3)
      • Reviewer Profile:
      • First time user (3)

    Reviewed by 4 customers

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    5.0

    On first bottle of Low-dose Vit. K2

    By Ken a beliver golfer, caregiver

    from Houston, TX

    About Me First Time User, Health Conscious

    See all my reviews

    Pros

    • Simple To Take

    Cons

    • On The 1st Bottle Buthav

    Best Uses

    • Daily Use
    • Men
    • Older People

    Comments about Life Extension Low-Dose Vitamin K2 Menaquinone-7 (MK-7), 90 softgels:

    Wanted to increase my Vt. K as I was out of the regular Bone Restore.

    Comment on this review

     
    4.0

    look like its help

    By dino

    from location

    About Me First Time User

    Pros

    • No Side Effects

    Cons

    • Results Lessen Over Time

    Best Uses

    • Daily Use
    • Men

    Comments about Life Extension Low-Dose Vitamin K2 Menaquinone-7 (MK-7), 90 softgels:

    i use it to prevent heart problem that already run in the family.i use it for almost two month,so i dont know the reasolt yet

    Comment on this review

     
    5.0

    Happy Coastsider

    By Happy Coastsider

    from San Mateo, Ca

    About Me Health Conscious, Regular User

    See all my reviews

    Pros

    • Simple To Take

    Cons

      Best Uses

      • Daily Use
      • Men
      • Older People
      • Women

      Comments about Life Extension Low-Dose Vitamin K2 Menaquinone-7 (MK-7), 90 softgels:

      My husband and I use this product daily and we are very happy with it.

      Comment on this review

      (1 of 2 customers found this review helpful)

       
      4.0

      Low Dose Vit K2

      By trishe

      from Lake Havasu City, AZ.

      About Me First Time User

      See all my reviews

      Pros

      • Simple To Take

      Cons

        Best Uses

          Comments about Life Extension Low-Dose Vitamin K2 Menaquinone-7 (MK-7), 90 softgels:

          After reading an article on Vit. K2 and it's use with taking calcium, I felt that I needed to take a bit more Vit. K2 so as to enable calcium not to build up in arterial areas. Hopefully my once a wk. addition will help over time. I take Bone-up and this extra bit of Vit. K2 should be an asset.

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