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CR Mimetic Longevity Formula

60 vegetarian capsules, Item# 01429

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CR Mimetic Longevity Formula
60 vegetarian capsules
Item Catalog Number: 01429

Life Extension has gone to extraordinary lengths to identify those compounds that simulate calorie restriction’s ability to trigger youthful gene expression— the process by which genes transmit signals that slow certain aspects of aging. In 2003, we introduced standardized extract of resveratrol. In 2009, we introduced the "other" resveratrol, pterostilbene, a compound whose effects were found to work in synergy with resveratrol to activate your longevity genes.

We’ve brought together the five known calorie restriction mimetics ... trans-resveratrol, trans-pterostilbene, quercetin, grape seed polyphenols, and black tea extract1-9 in one, high potency formula. And to that we’ve now added a sixth to formulate CR Mimetic!

This innovative formulation features the little-known flavonoid fisetin (which is most abundantly found in strawberries). It is the sixth compound shown to simulate a youthful gene expression pattern similar to calorie restriction10 without significant dietary modification.

Fisetin may also enhance the effects of resveratrol.11 Researchers have uncovered compelling evidence of fisetin’s ability to stabilize resveratrol by shielding it from metabolic breakdown11 ... thus extending its effects.

Fisetin has been shown to have the power to "switch on" powerful cell signaling molecules that support youthful gene expression, DNA protection, and healthy cellular function.10 Fisetin also supports aging neurons in the presence of oxidative stress.12-14

And each serving of CR Mimetic Longevity Formula contains fisetin in an amount equivalent to 2 cups of strawberries, helping to further emulate calorie restriction's favorable influence on your longevity genes.

This unique formula provides cutting-edge broad-spectrum support for youthful gene expression from the most scientifically validated, natural sources.

This supplement should be taken in conjunction with a healthy diet and regular exercise program. Results may vary.

References
Supplement Facts

Serving size 2 vegetarian capsules

Servings per container 30

Amount per serving

Trans-Resveratrol [from Japanese knotweed extract (root)]

250 mg

Trans-Pterostilbene (from pTeroPure®)

3 mg

Quercetin (as quercetin dihydrate)

150 mg

Masquelier’s® Original OPCs [single and condensed (2-5 units) of flavanols & polyphenols from grape seeds]

50 mg

Black tea decaffeinated extract (leaf) [standardized to 12% TF2a theaflavin fraction (36 mg), along with TF1, TF2b and TF3 theaflavin fractions]

300 mg

Fisetin [from wax tree extract (stem)]

48 mg

Other ingredients: vegetable cellulose (capsule), microcrystalline cellulose, silica, vegetable stearate.

pTeroPure® is a registered trademark of ChromaDex, Inc.
MASQUELIER’s® is a registered trademark of International Nutrition Company BV (INC), Loosdrecht, The Netherlands.

Dosage and Use
  • Take two capsules daily with or without food, or as recommended by a healthcare practitioner.
  • Can be taken together or in divided doses.
Caution

Consult with your doctor before using this product if you have a bleeding disorder, or if you are taking anticoagulant, antiplatelet, or diabetic medications.

Warnings

REVIEW SNAPSHOT®

by PowerReviews
Life ExtensionCR Mimetic Longevity Formula, 60 vegetarian capsules
 
4.3

(based on 14 reviews)

Ratings Distribution

  • 5 Stars

     

    (6)

  • 4 Stars

     

    (7)

  • 3 Stars

     

    (0)

  • 2 Stars

     

    (1)

  • 1 Stars

     

    (0)

92%

of respondents would recommend this to a friend.

Pros

  • No side effects (12)
  • Simple to take (12)
  • Produces results (7)

Cons

    Best Uses

    • Daily use (12)
    • Women (5)
    • Men (4)
    • Older people (4)
      • Reviewer Profile:
      • Regular user (9), Health conscious (7), First time user (3)

    Most Liked Positive Review

     

    I am glad this product is available

    Because the mimetic formula is such a powerful longevity formula, with so many amazing ingredients that would be too costly to purchase separately, I am pleased to be able to purchase it at a...Read complete review

    Because the mimetic formula is such a powerful longevity formula, with so many amazing ingredients that would be too costly to purchase separately, I am pleased to be able to purchase it at a good price.
    I trust this product, as I have been taking supplements from LEF for so many years, and enjoy outstanding health. I am 70 years old. I wish it was less expensive or would go on sale more often.

    VS

    Most Liked Negative Review

     

    Calorie restriction not work in primates

    The only long term study of calorie restriction in primates showed no longevity benefits over a normal healthy diet. Some of the ingredients may have health benfits, but there have been no studies done...Read complete review

    The only long term study of calorie restriction in primates showed no longevity benefits over a normal healthy diet. Some of the ingredients may have health benfits, but there have been no studies done with this product, so it is difficult to assess.
    I've tried it for years, and cannot say if it has been of any benefit.

    Reviewed by 14 customers

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    (1 of 2 customers found this review helpful)

     
    2.0

    Calorie restriction not work in primates

    By Brian

    from Washington, DC

    Pros

    • Easy To Use

    Cons

    • Not Effective
    • Proven Ineffective

    Best Uses

    • Daily Use

    Comments about Life Extension CR Mimetic Longevity Formula, 60 vegetarian capsules:

    The only long term study of calorie restriction in primates showed no longevity benefits over a normal healthy diet. Some of the ingredients may have health benfits, but there have been no studies done with this product, so it is difficult to assess.
    I've tried it for years, and cannot say if it has been of any benefit.

    Comment on this review

    (1 of 1 customers found this review helpful)

     
    4.0

    CR Mimetic Longevity Formula

    By Jane Bee

    from Georgia

    See all my reviews

    Pros

    • I Like The Combination
    • No Side Effects
    • Produces Results
    • Simple To Take

    Cons

      Best Uses

        Comments about Life Extension CR Mimetic Longevity Formula, 60 vegetarian capsules:

        It's easy to use. I like the fact that there are several compounds mixed into one pill, instead of having to take several pills to get the same effect.

        Comment on this review

        (2 of 2 customers found this review helpful)

         
        4.0

        This is a wonderful product

        By Ali

        from Massachusetts

        About Me First Time User

        See all my reviews

        Pros

        • No Side Effects
        • Simple To Take

        Cons

          Best Uses

          • Daily Use

          Comments about Life Extension CR Mimetic Longevity Formula, 60 vegetarian capsules:

          I like this product a lot because it contains 250 mg of resveratrol. This is much more resveratrol than the product I had been taking. I choose this version of LEF resveratrol formulas because it also contains other plant extracts that I have read about and wanted to try. I was happy to see them all in 1 product. Now I don't have to take a lot of additional pills and it cost less to buy them together in one product.

          Comment on this review

          (4 of 4 customers found this review helpful)

           
          5.0

          Awesome Product!

          By Ken

          from Lake Forest, CA

          About Me Health Conscious, Regular User

          Pros

          • No Side Effects
          • Simple To Take

          Cons

            Best Uses

            • Daily Use
            • Men
            • Older People
            • Women

            Comments about Life Extension CR Mimetic Longevity Formula, 60 vegetarian capsules:

            This is such a great product, as it combines an amazing SIX calorie restriction mimetic compounds in a single capsule. Of course, any benefits of taking it will be seen only in the long term, but for those of us who believe in the benefits of calorie restriction mimetics, this product is an absolute must!

            Comment on this review

            (0 of 1 customers found this review helpful)

             
            4.0

            CR Mimetic Longevity Formula

            By Linda the Nutritionist

            from Washington State

            About Me Health Conscious, Regular User

            See all my reviews

            Pros

            • No Side Effects
            • Simple To Take

            Cons

              Best Uses

              • Daily Use

              Comments about Life Extension CR Mimetic Longevity Formula, 60 vegetarian capsules:

              Great product and so easy to swallow.

              Comment on this review

              (0 of 1 customers found this review helpful)

               
              4.0

              good

              By DavidB

              from san francisco

              About Me First Time User

              See all my reviews

              Pros

              • No Side Effects

              Cons

                Best Uses

                • Daily Use

                Comments about Life Extension CR Mimetic Longevity Formula, 60 vegetarian capsules:

                the ingredients are great. the effects seem very mild.

                Comment on this review

                (4 of 4 customers found this review helpful)

                 
                5.0

                I am glad this product is available

                By Bonnie the healthy one

                from Chandler, Arizona

                About Me Health Conscious, LEF member for 15-20years, Regular User

                See all my reviews

                Pros

                • It does what it says
                • No adverse affects
                • No Side Effects
                • Produces Results
                • Simple To Take

                Cons

                • Pricey

                Best Uses

                • Older People
                • Something I need
                • Women

                Comments about Life Extension CR Mimetic Longevity Formula, 60 vegetarian capsules:

                Because the mimetic formula is such a powerful longevity formula, with so many amazing ingredients that would be too costly to purchase separately, I am pleased to be able to purchase it at a good price.
                I trust this product, as I have been taking supplements from LEF for so many years, and enjoy outstanding health. I am 70 years old. I wish it was less expensive or would go on sale more often.

                Comment on this review

                (1 of 1 customers found this review helpful)

                 
                4.0

                Highly Recommended

                By YouthExtender

                from Lawton, OK

                About Me Regular User

                Pros

                • No Side Effects
                • Produces Results
                • Simple To Take

                Cons

                  Best Uses

                  • Daily Use

                  Comments about Life Extension CR Mimetic Longevity Formula, 60 vegetarian capsules:

                  Resveratrol has extended lifespan/youthspan in every species on which it has been tested. CR Mimetic, Mitochondrial Energy Optimizer, Omega 3s, antioxidants, vitamins and minerals are essential in my supplement protocol.

                  Comment on this review

                  (2 of 2 customers found this review helpful)

                   
                  5.0

                  the theory behind has been shown

                  By JuJu

                  from Tacoma, WA

                  About Me First Time User, Health Conscious

                  Pros

                  • Simple To Take

                  Cons

                  • Wait to see results

                  Best Uses

                  • Daily Use
                  • Men
                  • Women

                  Comments about Life Extension CR Mimetic Longevity Formula, 60 vegetarian capsules:

                  I believe in the facts behind this product ...since it is for longevity don't expect to see immediate rsults :)

                  Comment on this review

                  (0 of 1 customers found this review helpful)

                   
                  4.0

                  Great Product

                  By Shari Fitness

                  from Boca Raton, FL

                  About Me Regular User

                  Pros

                  • No Side Effects
                  • Produces Results
                  • Simple To Take

                  Cons

                    Best Uses

                    • Daily Use
                    • Men
                    • Older People
                    • Women

                    Comments about Life Extension CR Mimetic Longevity Formula, 60 vegetarian capsules:

                    A great addition to my daily vitamins!

                    Comment on this review

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