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The requested item 01224 is obsolete and has been replaced. The new item is 01724.

Super K with Advanced K2 Complex

90 softgels, Item# 01724

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Super K with Advanced K2 Complex
90 softgels
Item Catalog Number: 01724

An abundance of human clinical data reveals that vitamin K plays a critical role in maintaining healthy bone density by facilitating the transport of calcium from the bloodstream into the bone.6-10 Vitamin K is also required by calcium-regulating proteins in the arteries. Matrix Gla-protein (MGP) is a vitamin K-dependent protein, and it must be carboxylated to function properly. Poor vitamin K status leads to inactive uncarboxylated MGP (ucMGP), which accumulates at sites of arterial calcification.11,12 Since MGP is a potent local inhibitor of arterial calcification, MGP is important in relation to the health of the entire cardiovascular system. Without adequate vitamin K, calcium in the blood can bind to the arterial wall resulting in calcification.13,14 As people age, even a subclinical vitamin K deficiency can pose risks to the vascular system. Poor vitamin K status also results in increased circulating levels of undercarboxylated osteocalcin that is shown to be associated with increased bone loss in postmenopausal women.15,16

Humans get most of their vitamin K from green vegetables in the form of vitamin K1. The problem is that K1 is tightly bound to plant fiber and only a small fraction absorbs into the bloodstream.17-19

Vitamin K2 (menaquinones) is found in meat, eggs, and dairy products and is also made by bacteria in the human gut, which provides a certain amount of the human vitamin K requirement.20 Human studies show that vitamin K2 is up to ten times more bioavailable than K1. Vitamin K2 remains biologically active in the body far longer than K1. For instance, K1 is rapidly cleared by the liver within eight hours, whereas measurable levels of K2 (MK-7) have been detected 72 hours after ingestion.10

The Rotterdam Heart Study, a large-scale, well-controlled clinical trial that tracked 4,800 participants for seven years, revealed that participants who ingested the greatest quantities of vitamin K2 in their diet experienced a better cardiovascular condition than people who ingested the least.21 High intakes of vitamin K2 also corresponded to less calcium deposition in the aorta, whereas participants who ingested less K2 were more likely to show moderate or severe calcification. Animal studies suggest vitamin K intake not only blocks the progress of further calcium accumulation, but also induces 37% regression of preformed arterial calcification.22,23

Ideal Forms of Vitamin K2

In recent years, two forms of vitamin K2 have been extensively researched and the findings reveal vastly improved effects compared to K1. The MK-4 form of vitamin K2 is the most rapidly absorbed and is now routinely used in Japan to maintain healthy bone density. MK-4, however, only remains active in the blood for a few hours. The MK-7 form of K2, on the other hand, remains bioavailable to the human body over a sustained 24-hour period24 and to higher levels (seven- to eightfold) during prolonged intake.10 Both MK-4 and MK-7 have demonstrated remarkable health benefits when studied in human populations.

The Most Complete Vitamin K Formula

Vitamin K1 is the form found in plants and vegetables and should be part of most people’s daily supplement regimen. Even more important is inclusion of the MK-4 and MK-7 forms of vitamin K2.

Based on data substantiating the long-acting effects of MK-7, it is now possible to ingest fewer total micrograms of vitamin K but achieve far higher sustained blood levels of this critical nutrient.

The latest Super K with Advanced K2 Complex formula provides vitamin K1 and the MK-4 and MK-7 forms of vitamin K2 in just one daily softgel. The virtue of this formula is that it provides the precise amount of the long-acting MK-7 form of vitamin K2 that recent human studies have shown provides optimal K2 levels over a 24-hour period. The MK-4 is included to provide the rapid increase in vitamin K blood levels that may account for its beneficial effects in certain studies.

References
Supplement Facts

Serving Size 1 softgel

Servings Per Container 90

Amount Per Serving

Vitamin C (as Ascorbyl palmitate)

10 mg

Vitamin K activity

2200 mcg

From:

 

Vitamin K1 (as phytonadione)

1000 mcg

Vitamin K2 (as menaquinone-4)

1000 mcg

Vitamin K2 (as menaquinone-7)

200 mcg

Other ingredients: extra virgin olive oil, gelatin, glycerin, beeswax, purified water, carob color.

 

Dosage and Use
  • Take one softgel daily with food, or as recommended by a healthcare practitioner.
Caution

If you are taking anti-coagulant or anti-platelet medications, or have a bleeding disorder, consult with your healthcare provider before taking this product.

Warnings

REVIEW SNAPSHOT®

by PowerReviews
Life ExtensionSuper K with Advanced K2 Complex, 90 softgels
 
4.9

(based on 12 reviews)

Ratings Distribution

  • 5 Stars

     

    (11)

  • 4 Stars

     

    (1)

  • 3 Stars

     

    (0)

  • 2 Stars

     

    (0)

  • 1 Stars

     

    (0)

100%

of respondents would recommend this to a friend.

Pros

  • Simple to take (12)
  • No side effects (10)
  • Produces results (8)
  • Acts quickly (5)

Cons

    Best Uses

    • Daily use (12)
    • Older people (9)
    • Women (9)
    • Men (7)
      • Reviewer Profile:
      • Health conscious (12), Regular user (9)

    Reviewed by 12 customers

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    Displaying reviews 1-10

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    (5 of 5 customers found this review helpful)

     
    4.0

    Not sure it needs K1

    By Cheapman

    from Houston

    About Me Health Conscious, Regular User

    See all my reviews

    Pros

    • Produces Results
    • Simple To Take

    Cons

      Best Uses

      • Daily Use

      Comments about Life Extension Super K with Advanced K2 Complex, 90 softgels:

      I was taking LE's vitamin D/K/iodine product. But, I was unsure about taking iodine. It is controversial. So, I switched to taking this plus a separate vitamin D capsule. I still get a small amount of iodine via the two-per-day captules.

      The fact that people need more vitamin K seems to be true. But, the amounts of each form seems to still be under debate. For example, a lot of authors say that K1 is generally not needed to be supplemented. And, K1, despite being in the K family, is very very different from K2. K1 deals with blood clotting, while K2 deals with calcium utilization.

      Now, of the K2, well, again, how much to take is controversial. MK-4 has a very short half life in the body. So, the 1000 mcg (1 mg) contained in the product may be negligible. MK-4 standalone supplmements are often 5 mg or more, and taken multiple times per day.

      That is among the reasons why MK-7 is more popular. You need a lot less of it, and it has a long half life. On the other hand, some reports seem to indicate that, if you take a lot of MK-4, multiple times per day, it is actually more effective than MK-7. But, I don't know this for sure, that is just what some reports say.

      In any case, the 200 mcg of MK-7 of this product seems to be a good dose. For some reason, LE only puts 100 mcg in that D/K/iodine product, so, I like this better for that reason too.

      So, bottom line is, I'm taking this for now. Along with, as I said, Two-per-day, vitamin D, and several others. But, dosage recommendations on vitamin K are still in debate and could change.

      Comment on this review

      (2 of 3 customers found this review helpful)

       
      5.0

      Excellent product

      By Phil

      from Memphis

      About Me Health Conscious, Medical Professional, Regular User

      See all my reviews

      Pros

      • Acts Quickly
      • No Side Effects
      • Simple To Take

      Cons

        Best Uses

        • Daily Use
        • Men
        • Older People
        • Women

        Comments about Life Extension Super K with Advanced K2 Complex, 90 softgels:

        This product is 'required' for any serious health conscious individual, to take every day.

        Comment on this review

        (2 of 2 customers found this review helpful)

         
        5.0

        Does the job!

        By Periwinkle

        from Chattanooga, TN

        About Me Health Conscious, Regular User

        See all my reviews

        Pros

        • No Side Effects
        • Produces Results
        • Simple To Take

        Cons

          Best Uses

          • Daily Use
          • Men
          • Older People
          • Women

          Comments about Life Extension Super K with Advanced K2 Complex, 90 softgels:

          Easy to take as it is a small pill.
          No after taste
          Arrives promptly so one never needs to run out!

          Comment on this review

          (3 of 3 customers found this review helpful)

           
          5.0

          Super k with advanced k2

          By Cupcake

          from Sebring, Fl

          About Me Health Conscious, Regular User

          See all my reviews

          Pros

          • Acts Quickly
          • No Side Effects
          • Produces Results
          • Simple To Take

          Cons

            Best Uses

            • Daily Use

            Comments about Life Extension Super K with Advanced K2 Complex, 90 softgels:

            Very easy to take only once a day with great results.

            Comment on this review

            (1 of 1 customers found this review helpful)

             
            5.0

            Excellent product

            By Lou

            from California

            About Me Health Conscious

            See all my reviews

            Pros

            • Excellent Formula
            • Simple To Take

            Cons

              Best Uses

              • Daily Use

              Comments about Life Extension Super K with Advanced K2 Complex, 90 softgels:

              I really like this formula. Last bone density test was improved...

              Service and delivery comments:

              Prompt delivery

              Comment on this review

              (2 of 2 customers found this review helpful)

               
              5.0

              This is an excellent product

              By Minga

              from Joplin, MO

              About Me Health Conscious, Regular User

              See all my reviews

              Pros

              • Acts Quickly
              • Good Taste
              • No Side Effects
              • Produces Results
              • Simple To Take

              Cons

                Best Uses

                • Daily Use
                • Men
                • Older People
                • Women

                Comments about Life Extension Super K with Advanced K2 Complex, 90 softgels:

                Vitamin K is important for good health, and this capsule is small and easy to take once daily with a meal.

                Comment on this review

                (2 of 2 customers found this review helpful)

                 
                5.0

                Super Dooper

                By Dr Dopey

                from Texas

                About Me Health Conscious, Regular User

                See all my reviews

                Pros

                • No Side Effects
                • Simple To Take

                Cons

                  Best Uses

                  • Daily Use
                  • Men
                  • Older People
                  • Women

                  Comments about Life Extension Super K with Advanced K2 Complex, 90 softgels:

                  Perhaps your annual physical might show some results...As for me, I feel GR8...
                  Use as directed...

                  Comment on this review

                  (3 of 3 customers found this review helpful)

                   
                  5.0

                  A lifetime fan

                  By *Small But Mighty

                  from Mililani, HI

                  About Me Health Conscious, Regular User

                  See all my reviews

                  Pros

                  • Acts Quickly
                  • Good Taste
                  • No Side Effects
                  • Produces Results
                  • Simple To Take

                  Cons

                    Best Uses

                    • Daily Use
                    • Men
                    • Older People
                    • Women

                    Comments about Life Extension Super K with Advanced K2 Complex, 90 softgels:

                    Convenient and such an important supplement!

                    Comment on this review

                    (2 of 2 customers found this review helpful)

                     
                    5.0

                    Very effective

                    By Roane

                    from Indianapolis, IN

                    About Me First Time User, Health Conscious

                    See all my reviews

                    Pros

                    • Acts Quickly
                    • No Side Effects
                    • Produces Results
                    • Simple To Take

                    Cons

                      Best Uses

                      • Daily Use
                      • Older People
                      • Women

                      Comments about Life Extension Super K with Advanced K2 Complex, 90 softgels:

                      Very effective!

                      Comment on this review

                      (3 of 4 customers found this review helpful)

                       
                      5.0

                      Super K

                      By Linda T

                      from Plantation FL

                      About Me Health Conscious, Post-menopausal Female, Regular User

                      See all my reviews

                      Pros

                      • Contains Most Amt Of K
                      • No Side Effects
                      • Produces Results
                      • Simple To Take
                      • The Best K Formula Around

                      Cons

                        Best Uses

                        • Daily Use
                        • Older People
                        • Women

                        Comments about Life Extension Super K with Advanced K2 Complex, 90 softgels:

                        Have been using this product for years as one of many supplements to help keep bones strong. My bone density scan showed improvement.

                        Comment on this review

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