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The requested item 00359 is obsolete and has been replaced. The new item is 01859.


1000 mg 60 liquid vegetarian capsules, Item# 01859


Retail price

$13.00 each

Save 25%

$9.75 each


Save 7%

$12.00 each

Save 30%

$9.00 each

1000 mg 60 liquid vegetarian capsules
Item Catalog Number:

Trimethylglycine (TMG) is also called glycine betaine, but the name trimethylglycine signifies that it has three methyl groups attached to each molecule of glycine. TMG was discovered to be beneficial to heart health back in the 1950s.146-150 TMG operates along a pathway similar to that of vitamin B12. It is a “methyl donor,” providing extra methyl groups to hasten the conversion of homocysteine back to methionine.151 When a TMG methyl group is donated to a molecule of homocysteine, it converts to the non-toxic amino acid, methionine.152-153 Research showing TMG’s ability to promote healthy levels of homocysteine, alone or in conjunction with other nutrients, confirms its status as an important nutrient for cardiovascular health.154-162 For example, in a recent cross-sectional survey study, participants who consumed >360 mg/d of TMG had, on average, 10% lower concentrations of homocysteine and 19% lower concentrations of C-reactive protein than those participants who consumed <260 mg/d.163

Supplement Facts

Serving Size 2 vegetarian liquid capsules

Servings Per Container 30

Amount Per Serving

Trimethylglycine (TMG) (as betaine anhydrous)

1000 mg

Other ingredients: glycerin, vegetable cellulose (capsule), purified water.

Dosage and Use
  • Take two capsules in the morning with or without food, or as recommended by a healthcare practitioner. 
  • TMG should be taken with co-factors B6, B12, and folic acid.

If muscle tension or headaches occur, reduce dose or discontinue product, and inform your physician if they do not subside.



by PowerReviews
Life ExtensionTMG, 1000 mg 60 liquid vegetarian capsules

(based on 1 review)

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Reviewed by 1 customer

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(0 of 1 customers found this review helpful)


Too expensive

By Cheapman

from Houston

About Me Health Conscious

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  • Easy on Stomach
  • Easy To Swallow
  • Effective
  • Simple To Take


    Best Uses

    • Daily Use

    Comments about Life Extension TMG, 1000 mg 60 liquid vegetarian capsules:

    TMG is great. I like buying from LEF, in general. But their price for TMG is just too high.

    This is a liquid capsule. Perhaps it has higher absorption than dry. I don't know. If it does, that might mean it is better. I can't say.

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