Feverfew (Tanacetum parthenium) is a small, daisy-like flower with a distinctively strong, bitter odor.1 Recent evidence has revealed that feverfew inhibits the production of several inflammatory mediators that may be involved in head discomfort including arachidonic acid, cyclooxygenase-2, TNF-α, IL-1, MCP-1.1,2,3
1. Goodyear-Smith F. Feverfew. Bachelor's buttons, Featherfew (Tanacetum parthenium L. aka Chrysanthemum parthenium L. aka Pyrethrum parthenium L.). J Prim Health Care. 2010;2(4):337.
2. Saranitzky E, White CM, Baker EL, Baker WL, Coleman CI. Feverfew for migraine prophylaxis: a systematic review. J Diet Suppl. 2009;6(2):91-103.
3. Chen CF, Leung AY. Gene response of human monocytic cells for the detection of antimigraine activity of feverfew extracts. Can J Physiol Pharmacol. 2007;85(11):1108-1115.