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12 Steps to Achieving Ultimate Health

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Recommendation #12:
Maintain Optimal Blood Glucose Levels

Blood glucose spikes, which commonly occur after eating, can last for hours or even a whole day. Those spikes can unfavorably alter gene expression in a way that may accelerate the processes of aging.1,2

By contrast, scientists have established that maintaining fasting glucose levels in the range of 70-85 mg/dL and not allowing after-meal glucose levels to spike higher than 40 mg/dL over the fasting value, favorably influences the body’s longevity genes. 3-7

Calorie restriction has yielded robust extensions in life span, along with sharply lower risks of health issues. Yet some people, even when following reduced-calorie diets, still create too much glucose internally due to excess glucose-6-phosphatase, an enzyme, which prompts the release of additional stored glucose from tissues, even though there is already abundant glucose in the blood.

Fortunately, there are several proven ways to achieve healthy glucose levels that do not require calorie restriction. And many approaches that promote healthy glucose levels also promote healthy levels of insulin,8-11 LDL,9,12-16 triglycerides,17-19 and C-reactive protein20 — thus promoting better overall health.

Many Life Extension members already use nutrients, hormones, and drugs that encourage healthy insulin sensitivity, which facilitates healthier glucose levels.21-28 Yet too many health-conscious members are still not maintaining blood glucose levels within optimal range.

Life Extension urges all members to enact an aggressive personal program designed to obtain fasting glucose levels at the healthy ranges of 80-85mg/dL (or lower). For healthy, after- meal blood glucose reading, look for a normal, in-range reading that increases no more than 40 mg/dL above your fasting value. This means if your fasting glucose is 80, your after-meal glucose should be no higher than 120 mg/dL.

Maintaining these levels provides a profoundly effective, anti-aging impact as well as weight management benefits.

Green Coffee Bean Extract (GCA)

A standardized green coffee bean extract has been shown to be an effective support for healthy blood glucose levels already within normal range via novel mechanisms previously unavailable.29,30

Scientific studies have clearly demonstrated that green coffee bean extract targets a healthy response to blood sugar.

For example, clinical research found that a dose of 400 mg of green coffee bean extract encouraged healthy after meal blood glucose levels.29 Further research has suggested the compound responsible for this beneficial action on glucose metabolism is chlorogenic acid, which is found abundantly in raw coffee beans.

Chlorogenic acid inhibits the enzyme glucose-6-phosphatase, which positively impacts glucose in the body.30,31 This unique dual property of chlorogenic acid provides a powerful new weapon in our quest to attain optimal fasting and postprandial glucose levels.

Evidence has revealed that chlorogenic acid favorably modulates gene expression to enhance the activity of liver cells and increase levels of the hormone adiponectin, which enhances the body’s response to blood glucose and supports heart health.32

If green coffee bean extract only optimized after-meal glucose levels, it would be well worth considering for anyone looking to achieve glucose levels within normal range. But as with so many other natural polyphenols, chlorogenic acid has demonstrated a wide range of additional protective properties.33-37

Green coffee bean extract also supplies the antioxidant compound ferulic acid, that has been shown to support healthy blood glucose levels already within normal range in tandem with chlorogenic acid.38

The potency of green coffee bean extract is now available as a natural compound called CoffeeGenic® Green Coffee Extract (GCA). It is produced from organically grown beans through a patented extraction process and standardized to deliver 50% chlorogenic acids … an extraordinarily high proportion of chlorogenic acid for maximum potency.

For optimal benefit, one vegetarian capsule of CoffeeGenic® Green Coffee Extract should be taken before heavy meals.

A bottle of 90 vegetarian capsules, 200 mg each, retails for the reduced price of $25.00. If a member buys 4 bottles, the price is further reduced to just $16.50 a bottle. A bottle of 90 vegetarian capsules, 400 mg each, retails for the reduced price of $38.00. If a member buys 4 bottles, the price is further reduced to just $25.50 a bottle.

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