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Recommendation #3:
Maintain Optimal CoQ10 Blood Levels

Life Extension introduced coenzyme Q10 to the U.S. in 1983. Since then we have consistently introduced more potent, more absorbable forms of this critical nutrient. The reason is simple.

About 95% of cellular energy is produced from structures in your cells called mitochondria. Coenzyme Q10 is incorporated into the mitochondria of your cells where it facilitates the transformation of fats and sugars into energy. A large body of scientific evidence shows that CoQ10’s ability to restore mitochondrial function has a profound effect on one’s overall health.1-3 Coenzyme Q10 produces beneficial effects to the heart, 3-21 brain,3,22-26 kidneys,27-29 and other tissues.3,7,30-40

The Ubiquinol Form of CoQ10

Ubiquinol is the biologically superior form of CoQ10 because it’s an electron donor, which makes it a very effective neutralizer of free radicals and the only form of CoQ10 that scavenges lipid peroxyl radicals that can damage the polyunsaturated fatty acids of your cell membranes.

Super Ubiquinol CoQ10 with Enhanced Mitochondrial Support™

When CoQ10 levels diminish, the ability of cells to sustain even basic metabolic functions is impaired. Life Extension has taken the biologically superior ubiquinol form of CoQ10 and combined it with a compound called PrimaVie® Shilajit that research shows doubles levels of CoQ10 in the mitochondria.41 Shilajit has been shown to restore and sustain cellular energy.

Shilajit and Mitochondrial Metabolism

Scientific analysis shows that shilajit itself is rich in essential compounds that promote mitochondrial metabolism. Part of its beneficial effects derive from its ability to help the mitochondria convert fats and sugars into adenosine triphosphate, or ATP … the cell’s main source of energy. Combining ubiquinol CoQ10 with shilajit generates a powerful synergy that supports more youthful cellular energy production than CoQ10 alone.

CoQ10 Plus Shilajit

The latest studies show that when shilajit is combined with CoQ10, cellular energy gains substantially increase. In a breakthrough preliminary study, combining CoQ10 with shilajit produced a 56% increase in cellular energy production in the brain (40% better than CoQ10 alone) … and 144% increase in muscle (27% better than CoQ10 alone).42

Researchers have found that shilajit works to boost CoQ10’s beneficial effects two ways:

  1. By stabilizing CoQ10 in its superior ubiquinol form, thereby prolonging its action at the cellular level.43,44
  2. And by facilitating more efficient delivery of CoQ10 into the mitochondria, resulting in greater cellular energy output.45-49

CoQ10 and Statin Drugs

Heart cells have a high-energy demand, and many clinical studies have investigated the role of CoQ10 on cardiac function. Efficacy has been shown in studies when CoQ10 was used for cardiovascular problems.50-56 Scientists have also found that CoQ10 provides benefits to other organs whose cells require high-level energy metabolism such as the brain and kidneys.1,57-60

One reason more people supplement with coenzyme Q10 now than ever before is the increased awareness that statin drugs (used to lower LDL and cholesterol) deplete the body of CoQ10.61-66

Normal aging, however, can result in an even greater reduction in CoQ10 than that caused by statin drugs.67-71 While statin drugs have been shown to reduce blood plasma levels of CoQ10 by 40%, the aging process can reduce CoQ10 levels in your heart muscle wall by 72%.72

The retail price for a 100-count bottle of 50-mg Super Ubiquinol CoQ10 with Enhanced Mitochondrial Support™ is $58.00. If a member of the Life Extension Foundation buys four bottles, the price is reduced to $39.75 per bottle. Each bottle lasts most people about two months based on taking one capsule twice a day.

(Refer to this chart for a comparison using different forms of CoQ10).

Some members who want to take higher doses use the 100mg or 200 mg size of this unique formulation. The retail price for a bottle containing 60 softgels of 100 mg Super Ubiquinol CoQ10 with Enhanced Mitochondrial Support™ is $62.00. A 30-count bottle of 200 mg softgels also retails for $62.00. If a member buys four bottles of 100 mg or 200 mg Super Ubiquinol, the price is reduced to $42.00 per bottle. The significantly higher cellular energy gains make these novel CoQ10 formulations a tremendous value “per absorbed milligram.”

PrimaVie® is a registered trademark of Natreon, Inc.

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