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Recommendation #6:
Restore Youthful Hormone Balance

Taking vitamins alone may not make you feel better if you suffer from a hormone imbalance. Hormone balance is critical to maintaining health in women and men over age 35.

Aging men and women are often DHEA deficient.1-5 Men over age 40 often have too little free testosterone and less than optimal estrogen levels.6-10 Aging women need to balance their progesterone and estrogen levels.

The proper blood tests can provide the data needed to design an individualized hormone modulation program.

Life Extension offers low-cost blood test panels designed to help provide the biological information needed to safely achieve youthful hormone balance. The good news is that as more Americans have their blood tested to assess their hormone status, the prices of these blood tests have dropped so they are affordable to just about everyone. To order a comprehensive Male or Female Blood Test Panel, call 1-800-208-3444.

Once you receive your blood test results, you can take them to your doctor or talk to a Life Extension Health
Advisor about the different options available to you. Health Advisors are available by calling 1-800-226-2370.

The Most Popular Hormone Supplement

The Life Extension Foundation introduced the anti-aging benefits of dehydroepiandrosterone (DHEA) to its members in 1981. This hormone did not become credible to the medical establishment until 1996, when the New York Academy of Sciences published a textbook entitled DHEA and Aging that provided scientific validation for many of DHEA’s effects. The general public learned about DHEA later that same year when its benefits were touted in the media and in several best-selling books.

DHEA is the body’s most abundant circulating hormone. Unfortunately, research has shown that DHEA production peaks by age 25 and drops dramatically each year thereafter. By age 70 most people’s DHEA levels have declined by over 80%, leading to hormonal imbalances that can affect quality of life.11 These kinds of imbalances also occur with other critical hormones in our aging bodies such as testosterone, estrogen, and progesterone.

Thousands of studies have been published showing how DHEA may help to retard the effects of aging and promote longevity. Considering DHEA’s potential benefits, many researchers advocate taking DHEA supplements to regain youthful circulating concentrations of this critical hormone.11 To achieve the DHEA levels of a 25-year-old, men normally take 25-50 mg a day, while women usually need only 15-25 mg a day.

In addition, a DHEA metabolite called 7-Keto® DHEA demonstrates improved immune function 12 and a safe increase in fat-metabolizing enzymes in the liver.13-15 One study showed that people who consumed 200 mg of 7-Keto® DHEA lost more weight than those who took a placebo. Both groups followed a diet and exercise program.16

All of Life Extension’s DHEA supplements are manufactured under cGMP (current Good Manufacturing Practice) conditions.

For information about the different forms and potencies of DHEA, refer to the Hormones section of this Directory.

Caution: Do not use DHEA if you are at risk for or have been diagnosed with any type of hormonal cancer, such as prostate or breast cancer. Before initiating DHEA , refer to the DHEA Precautions for Men and DHEA Precautions for Women in the Hormones section of this Directory.

A Natural Approach for Men

Sexual stimulation begins in the brain when testosterone binds to cell-receptor sites to ignite a cascade of pleasure-inducing biochemical events. Testosterone promotes sexual desire and then facilitates performance, sensation and sexual climax. Men with low testosterone routinely suffer from a decreased sex drive and decreased libido. Low testosterone has also been linked to a host of age-related problems.

One reason aging males become testosterone-deficient is the conversion of testosterone to estrogen. A natural method of boosting free testosterone levels is to block the aromatase enzyme that catalyzes the conversion of testosterone to estrogen. A flavonoid called chrysin is an aromatase inhibitor.17

Another reason why aging men are testosterone-deficient is a blood component called sex hormone-binding globulin (SHBG) which binds to free testosterone, rendering it biologically inactive. Research has found that Urtica dioica (stinging nettle) has a greater affinity for SHBG than testosterone.18,19 As a result, stinging nettle binds to SHBG and helps increase the level of free testosterone.18

A formula called Super MiraForte with Standardized Lignans contains high concentrations of chrysin, Bioperine®, stinging & dwarf nettle, and Muira puama extracts. To augment the natural protective effects of these ingredients, a standardized lignan extract from Norwegian spruce is used in Super MiraForte. These lignans convert to enterolactone in the intestine that is then rapidly absorbed into the bloodstream where it provides significant biological effects.20 Enterolactone has demonstrated anti-estrogen and anti-DHT effects that are of particular importance for the aging prostate gland.21,22

Super MiraForte with Standardized Lignans is designed to help re-establish more youthful testosterone levels. A bottle containing 120 capsules retails for $62.00. If a Life Extension member buys four bottles, the price is reduced to $42.00 per bottle. The suggested dose is two capsules, twice per day. For more information, refer to the Hormones section of this Directory. (Item #01698)

Caution: If you are taking any medication, use only under physician supervision. Men with existing prostate cancer may not be able to use this product. Elevations in free testosterone can unmask an occult (hidden) prostate cancer. Anyone with this concern should have a baseline PSA prior to using this product and a follow-up PSA test 60 days later. If a significant elevation of PSA is found, discontinue this product and advise physician. Do not take more than 15 mg per day of Bioperine®.

Bioperine® is a registered trademark of Sabinsa Corp.

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