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Recommendation #6:
Restore Youthful Hormone Balance

A Natural Approach for Women

Roughly half of all women live without optimal sexual function and libido.23 A woman’s loss of sexual vitality is related to a number of key factors, including suboptimal levels of sex hormones, neurotransmitters, and nitric oxide; and increased levels of pro-inflammatory cytokines and monoamine oxidase.

A state-of-the-art formulation of natural botanical extracts has been developed to modulate these underlying mechanisms.

Botanical Support for Women’s Sexual Function

A formula called Advanced Natural Sex for Women® 50+ introduces a unique phyto blend that targets and supports the mechanisms that promote healthy sexual function and libido. This formula includes Cordyceps, a mushroom extract that modulates the levels of sex hormones and promotes their downstream flow, boosts mitochondrial energy and sex interest by increasing adenosine triphosphate (ATP) production, supports vaginal lubrication and sexual function by promoting nitric oxide, and inhibits pro-inflammatory cytokines that can dampen sexual desire. In placebo-controlled studies, scientists documented that Cordyceps improved sexual function and desire in 86% of women — in 40 days!24

Advanced Natural Sex for Women® 50+ also contains the plant root extract Maca (Lepidium meyenii).

Cultivated for over 2,000 years, Maca has now been shown to modulate levels and flow of sex hormones, support adrenal function, and promote libido and sexual pleasure by helping to optimize brain neurotransmitters and monoamine oxidase (MAO) levels. Women who took Maca scored over 35% better than placebo subjects on a standard sexual function and libido scale after just 6 weeks!25

Menopausal Relief and Enhanced Sexual Health

Menopausal transition is considered the most difficult time for a woman to remain sexually active. In addition to the hot flashes and fatigue, vaginal dryness and loss of libido often interfere with sexual function.

Advanced Natural Sex for Women ® 50+ also contains three herbal root extracts used for over 400 years in Korea to help inhibit symptoms of menopause:

Phlomis umbrosa

Cyanchum wilfordii

Angelica gigas

Scientists found that when these three natural botanicals are uniquely blended then hot water extracted, they balance estrogenic activity in just those target tissues specifically related to menopausal symptoms.26 In a double-blind, placebo-controlled study, this special formulation ( EstroG-100™) helped inhibit menopausal symptoms by 62% in just 12 weeks!26

For menopausal relief and enhanced sexual health, a daily dose of three capsules of Advanced Natural Sex for Women®50+ is suggested. A bottle of 90 vegetarian capsules retails for $59.00. If a member purchases four bottles, the price is reduced to only$34.00 per bottle. For further information about this formulation, refer to the Hormones and Special Purpose sections of this Directory.


The complicated cascade of reactions that produces all steroid hormones, like DHEA and testosterone, begins with pregnenolone. Through the action of the enzyme desmolase, cholesterol converts into pregnenolone. This is then followed by an array of enzymatic activity that produces critical hormones for managing many aspects of human physiology.

However, pregnenolone is much more than the “mother” hormone of all steroids. Pregnenolone was originally thought to be produced only in the adrenal glands, ovaries and testes. Surprisingly, the central nervous system (brain and spinal cord) also synthesizes this hormone.27

The discovery that certain steroids are produced and act in the central nervous system has led to the term “neurosteroids.”28 Another term — “neuroactive steroids” — is often used for hormones that may be manufactured elsewhere in the body but have potent actions in the nervous system. 29 Pregnenolone fits both of these descriptions.

As a neurosteroid, pregnenolone may offer important neuroprotection properties. Researchers have noticed that many neurodegenerative changes are associated with low levels of pregnenolone and other steroids derived from it.30-32

Even more remarkable, researchers have also shown that pregnenolone increases brain levels of acetylcholine, a key neurotransmitter required for optimal brain function, creating new memories and recalling old information.32

For all of these reasons, Life Extension places pregnenolone in our top nutrient suggestions, believing it to be an important part of a healthy brain and longevity supplement regimen.

A bottle of Life Extension’s Pregnenolone contains 100 50 mg capsules and retails for $26.00. If a member buys four bottles, the price is reduced to $16.50.

Caution: Pregnenolone may affect levels of other hormones, such as progesterone, estrogen, testosterone and/or DHEA. Do not take this product if you have a history of seizures. Do not take this product if you have breast cancer, prostate cancer, or other hormone-sensitive diseases.

Comprehensive Hormone Replacement Options

To learn about comprehensive hormone modulation for aging men or women, refer to the Disease Prevention and Treatment book. Men should refer to the following chapters in the Disease Prevention and Treatment book:

  • Male Hormone Restoration
  • DHEA Replacement

Women should refer to the two following chapters in the Disease Prevention and Treatment book:

  • Female Hormone Restoration
  • DHEA Replacement

Members can also discuss natural hormone balancing with one of our Life Extension Health Advisors by calling 1-800-226-2370.

The best way of determining your natural hormone needs is through the comprehensive Male or Female Blood Test Panel. To inquire about ordering these blood tests, call 1-800-208-3444.

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