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Recommendation Number 7:

Bone Restore

Calcium Supplements For Women And Men

DOSAGE: 5 capsules at dinner or before bedtime.

Protecting Your Bones (Women and Men)

Why do those who take calcium supplements still suffer from a loss of bone mineral density? One reason is that most people do not take enough calcium to offset the amount being lost in the course of normal aging.

Most people don’t realize that many calcium supplements contain relatively little calcium. Calcium citrate, for example, consists of 22% calcium and 78% citric acid. That means 1,000 mg of calcium citrate provides only 220 mg of elemental calcium.

Another problem overlooked by most doctors is the fact that bone density loss is not just associated with calcium deficiency, but also with an insufficient intake of a host of other nutrients including magnesium and vitamin D3.1-6 In order for calcium to help maintain healthy bones, adequate amounts of vitamin D33,7, zinc8-10, magnesium11, manganese12, and other nutrients should be available so that calcium and phosphorus can be incorporated into the bone matrix. Additionally, many forms of calcium are not particularly well absorbed.13-15

While loss of bone mineral density is more commonly experienced by women, aging men can also have this issue.16 Both men and women may suffer significant deficits of magnesium if they do not supplement. Magnesium is not only needed to maintain strong bones, but it is critical to promoting a healthy vascular system.17,18 In fact, magnesium is critical for facilitating hundreds of enzymatic reactions that our bodies require to maintain optimal health.19,20

Just five capsules of Bone Restore provide

To overcome the impediments that preclude aging adults from achieving optimal calcium status, Life Extension offers a proprietary comprehensive mineral formula called Bone Restore which has been designed to support healthy bone density and strength. Bone Restore provides 1,200 elemental milligrams of calcium from three different forms, along with the critically important nutrients magnesium,11 boron,1, 6,21,22 zinc8-10,23, silicon,24-26 manganese12 and Vitamin D7,27-30 needed for healthy bones.

In fact, the boron in this formula, called FruiteX B® Osteo-Boron®, is a natural boron/carbohydrate complex, similar to what is found in fruits and vegetables and is more bioavailable than boron citrate. Scientific research has established the beneficial effects of boron on the strength of bones and joints.31-33

One reason why aging people suffer bone loss even though they are taking calcium supplements is that they may not be absorbing enough elemental calcium. Bone Restore provides calcium in capsule form to ensure that it breaks down fully in the digestive tract. Unlike calcium tablets, these capsules burst open within five minutes of swallowing, making the minerals and vitamin D3 immediately available for absorption.

Women should take five capsules daily of Bone Restore, whereas men may only require three to four capsules daily. Maintaining an optimal vitamin D blood level, ensuring adequate vitamin K intake, and maintaining youthful hormone balance also helps maximize bone density.

More Info on Bone Health

References

1. Nielsen FH. Studies on the relationship between boron and magnesium, which possibly affects the formation and maintenance of bones. Magnes Trace Elem. 1990;9(2):61-9.

2. Tucker KL. Dietary intake and bone status with aging. Curr Pharm Des.2003;9(32):2687-704.

3. Hegsted M, Keenan MJ, et al. Effect of boron on vitamin D deficient rats. Biol Trace Elem Res 28:243-55, 1991.

4. Stendig-Lindberg G, Tepper R, Leichter I. Trabecular bone density in a two year controlled trial of peroral magnesium in osteoporosis. Magnes Res. 1993 Jun;6(2):155-63.

5. Abraham GE, Grewal H. A total dietary program emphasizing magnesium instead of calcium. Effect on the mineral density of calcaneous bone in postmenopausal women on hormonal therapy. J Reprod Med. 1990 May;35(5):503-7.

6. Tranquilli AL, Lucino E, Garzetti GG, et al. Calcium, phosphorus and magnesium intakes correlate with bone mineral content in postmenopausal women. Gynecol Endocrinol. 1994 Mar;8(1):55-8.

7. Holick MF. Environmental factors that influence the cutaneous production of vitamin D. Am J Clin Nutr. 1995 Mar;61(3 Suppl):638S-45S.

8. Mutlu M, Argun M, Kilic E, et al. Magnesium, zinc and copper status in osteoporotic, osteopenic and normal post-menopausal women. J Int Med Res. 2007 Sep-Oct;35(5):692-5.

9. Ryz NR, Weiler HA, Taylor CG. Zinc deficiency reduces bone mineral density in the spine of young adult rats: a pilot study. Ann Nutr Metab. 2009;54(3):218-26.

10. Jamieson JA, Taylor CG, Weiler HA. Marginal zinc deficiency exacerbates bone lead accumulation and high dietary zinc attenuates lead accumulation at the expense of bone density in growing rats. Toxic Sci. 2006 Jul;92(1):286-94.

11. PDR for Nutritional Supplements, 1st ed. Montvale, NJ: Medical Economics Co.; 2001:288-95.

12. Strause L, Saltman P, Smith KT, et al. Spinal bone loss in post- menopausal women supplemented with calcium and trace minerals. JNutr. 1994 Jul;124(7):1060-4.

13. Ishitani K, Itakura E, Goto S, et al. Calcium absorption from the ingestion of coral-derived calcium by humans. J Nutr Sci Vitaminol (Tokyo). 1999 Oct;45(5):509-17.

14. Classen HG, Schutte K, Schimatschek HF. Different effects of three high-dose oral calcium salts on acid-base metabolism, plasma electrolytes and urine parameters of rats. Methods Find Exp Clin Pharmacol. 1995 Sep;17(7):437-42.

15. Wood RJ, Serfaty-Lacrosniere C. Gastric acidity, atrophic gastritis, and calcium absorption. Nutr Rev. 1992 Feb;50(2):33-40.

16. Lopes RF, Ferreira SA, Coeli CM, et al. Low body mass index and declining sex steroids explain most age-related bone loss in Brazilian men. Osteoporos Int. 2008 Nov 20. [Epub ahead of print] Osteoporos Int. 2009 Jul;20(7):1175-82.

17. Fuentes JC, Salmon AA, Silver MA. Acute and chronic oral magnesium supplementation: effects on endothelial function, exercise capacity, and quality of life in patients with symptomatic heart failure. Congest Heart Fail. 2006 Jan-Feb;12(1):9-13.

18. Pokan R, Hofmann P, von Duvillard SP et al. Oral magnesium therapy, exercise heart rate, exercise tolerance, and myocardial function in coronary artery disease patients. Br J Sports Med. 2006 Sep;40(9):773-8.

19. Rude RK. Magnesium deficiency: a cause of heterogeneous disease in humans. J Bone Miner Res. 1998 Apr;13(4):749-58. Review.

20. Fox C, Ramsoomair D, Carter C. Magnesium: its proven and potential clinical significance. South Med J. 2001 Dec;94(12):1195-201.

21. PDR for Nutritional Supplements, 1st ed. Montvale, NJ: Medical Economics Co.; 2001:60-3.

22. Nielsen FH: Studies on the relationship between boron and magnesium which possibly affects the formation and maintenance of bones. Magnes Trace Elem. 1990;9:61-9.

23. Yamaguchi M. Role of nutritional zinc in the prevention of osteoporosis. Mol Cell Biochem. 2009 Dec 25. [Epub ahead of print]

24. Reffitt DM, Ogston N, Jugdaohsingh R, et al. Orthosilicic acid stimulates collagen type 1 synthesis and osteoblastic differentiation in human osteoblast-like cells in vitro. Bone. 2003 Feb;32(2):127-35.

25. Eisinger J, Clairet D. Effects of silicon, fluoride, etidronate and magnesium on bone mineral density: a retrospective study. Magnes Res. 1993 Sep;6(3):247-9.

26. Kim MH, Bae YJ, Choi MKet al. Silicon supplementation improves the bone mineral density of calcium-deficient ovariectomized rats by reducing bone resorption. Biol Trace Elem Res. 2009 Jun;128(3):239-47. Epub 2008 Nov 27.

27. Binkley N. A perspective on male osteoporosis. Best Pract Res Clin Rheumatol. 2009 Dec;23(6):755-68.

28. Lips P, Bouillon R, van Schoor NM, et al. Reducing fracture risk with calcium and vitamin D. Clin Endocrinol (Oxf). 2009 Sep 10. [Epub ahead of print]

29. Bischoff-Ferrari HA, Staehelin HB. Importance of vitamin D and calcium at older age. Int J Vitam Nutr Res. 2008 Dec;78(6):286-92. Review.

30. Hirani V, Tull K, Ali A, et al. Urgent action needed to improve vitamin D status among older people in England! Age Ageing. 2010 Jan;39(1):62-8.

31. Newnham RE. Essentiality of boron for healthy bones and joints. Environ Health Perspect. 1994 Nov;102 Suppl 7:83-5.

32. Devirian TA, Volpe SL. The physiological effects of dietary boron. Crit Rev Food Sci Nutr. 2003;43(2):219-31. Review.

33. Naghii MR, Samman S. The role of boron in nutrition and metabolism. Prog Food Nutr Sci. 1993 Oct-Dec;17(4):331-49. Review.

Top Ten Nutritional Supplements

1: Multivitamins and Minerals (Life Extension Mix™)

2: Omega-3 Fatty Acids (Fish Oil)

3: Coenzyme Q10 (CoQ10)

4: Mitochondrial Function (MEO)

5: Hormone Balance (DHEA)

6: Brain Cell Function (Cognitex)

7: Bone Health (for women and men)

7a: Prostate Health (for men only)

8: Neural and Hepatic Health (SAMe)

9: Cardiovascular Health (Aspirin)

10: Vitamin K, Gamma Tocopherol (Super Booster Softgels)

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*These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent any disease.

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