S-adenosylmethionine (SAMe)

Restore Youthful Methylation Patterns

Published research shows that methylation defects create a variety of age-related problems including neuronal and hepatic dysfunction.1-8 Enhancing healthy methylation facilitates healthy enzymatic life processes throughout the body.

SAMe (S-adenosylmethionine) is a critical methylation component and plays important roles in regulating neurotransmitters (brain chemicals) such as serotonin, melatonin, and dopamine.9 SAMe also participates in the making of DNA and cartilage.

Not only can SAMe enhance mood and alleviate melancholy, but it can also promote healthy joints.10-14 Since aging people often suffer joint discomfort and immobilization, SAMe addresses multiple problems people face as they grow older.15 An agency of the U.S. Department of Health and Human Services conducted a meticulous evaluation of SAMe in 2002. Their findings show that SAMe is effective in promoting good mood and bone and joint health.16

SAMe should be taken with cofactors vitamin B12 and folic acid.17 If you take Life Extension Mix™, Two-Per-Day (Recommendation #1) and/or the Life Extension Super Booster (Recommendation #10), you automatically get these cofactors.

Not all SAMe supplements are created equal. SAMe is an unstable molecule that requires special processing to ensure stability. Life Extension members can obtain premium-quality SAMe at competitive prices. A box of 20 400-mg tablets retails for $32.00. If a member buys six boxes, the price is reduced to $18.75 per box. Healthy people should take 400–800 mg daily.

Caution: SAMe should not be taken by those diagnosed with bipolar disorder.

More Info on Neural And Hepatic Health (SAMe)