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Recommendation Number 7a:
Ultra Natural Prostate with 5-Loxin® and Standardized Lignans
Prostate Health Supplements For Men Only

DOSAGE: 2 softgels daily divided between morning and evening, with or without food, or as recommended by a healthcare practitioner.

Maintain Healthy Prostate Function With Prostate Health Supplements

A huge percentage of men over age 50 suffer from prostate-induced discomforts.

The Ultra Natural Prostate Formula contains the most scientifically substantiated nutrients to help protect the prostate gland and maintain prostate health.*

Recently added to the formulas are standardized lignans from flax and the Norway spruce trees. These lignans convert to enterolactones in the intestine that are then absorbed into the bloodstream where they provide significant biological effects. Enterolactones have demonstrated anti-estrogen and anti-DHT effects that are of particular importance for the aging prostate gland.328-330

Prostate Health And 5-LOXIN

The eight other active ingredients in Ultra Natural Prostate Formula are:

5-LOXIN® boswellia extract. Published studies show that normal aging and
poor diet cause levels of a dangerous enzyme (5-lipoxygenase) to increase, which can affect prostate cells. 5-LOXIN is a patented extract from the boswellia plant that has been shown to suppress 5-lipoxygenase and other pro-inflammatory factors.331-335
Nettle root extract (Urtica dioica). In aging men, too much testosterone is converted to estrogen. Prostate cells are sensitive to estrogen’s growth stimulatory effects. Nettle rood helps protect prostate cells against the excess estrogen levels.338
Saw palmetto extract. A number of normal biological events in aging men affect prostate function and structure. Saw palmetto has been shown to interfere with DHT activity in the prostate, inhibit the alpha-adrenergic receptor inhibitor (to support normal urinary flow) and help control inflammatory actions in the prostate gland336,337*
Pygeum. Normal aging results in levels of certain prostaglandins increasing in the prostate gland. Pygeum africanum extract helps suppress these prostaglandins, keeping the prostate gland placid and promoting prostate health.339*
Beta-sitosterol. The most biologically active constituent of pygeum is beta-sitosterol. It is more cost effective to obtain beta-sitosterol from other plant sources for inclusion in a prostate health formula.340
Cernitin®. This European pollen extract has been shown to relax smooth muscle tone of the urethra, counteract DHT, and help regulate inflammatory reactions.341-345
Boron. This mineral helps protect bones, and has been shown to slow elevation of PSA, most probably by protecting against protein-degrading enzymes in the prostate gland.346,347
Lycopene. This carotenoid most commonly associated with tomato sauce helps maintain healthy DNA gene function in prostate cells.348-352

Prostate Function And Your Health

Ultra Natural Prostate Formula provides pharmaceutical-grade standardized plant extracts that have been shown to promote healthy prostate function. No other prostate protection formula provides such a broad array of nutrients to counteract the multiple factors involved in maintaining a healthy prostate gland.

The daily dose of two softgels of the new Ultra Natural Prostate Formula provides:

Saw palmetto (supercritical extract)	320 mg
Nettle root extract (Urtica dioica)	240 mg
Pygeum extract (11.7% pygeum sterols)	100 mg
5-LOXIN®	70 mg
Lycopene extract	10 mg
Phytosterol Complex (standardized to 26.6% beta-sitosterol)	678 mg
Boron (from citrate, glycinate, and aspartate)	3 mg
Cernitin®	252 mg
HMRlignan™ Norway Spruce lignan extract	13.9 mg
ActiFlax™ Flax lignan extract	6.25 mg

More Info on Prostate Health

Maintain Healthy Prostate Function With Prostate Health Supplements

Top Ten Nutritional Supplements

1: Multivitamins and Minerals
(Life Extension Mix™)

2: Omega-3 Fatty Acids (Fish Oil)

3: Coenzyme Q10 (CoQ10)

4: Mitochondrial Function (MEO)

5: Hormone Balance (DHEA)

6: Brain Cell Function (Cognitex)

7: Bone Health (for women and men)

7a: Prostate Health (for men only)

8: Neural and Hepatic Health (SAMe)

9: Cardiovascular Health (Aspirin)

10: Vitamin K, Gamma Tocopherol (Super Booster Softgels)

References

328. Heald CL, Ritchie MR, Bolton-Smith C, et al. Phyto-oestrogens and risk of prostate cancer in Scottish men. Br J Nutr. 2007 Aug;98(2):388-96. Epub 2007 Apr 3.

329. Hedelin M, Klint A, Chang ET, et al. Dietary phytoestrogen, serum enterolactone and risk of prostate cancer: the cancer prostate Sweden study (Sweden). Cancer Causes Control. 2006 Mar;17(2):169-80.

330. Low YL, Taylor JI, Grace PB, et al. Phytoestrogen exposure correlation with plasma estradiol in postmenopausal women in European Prospective Investigation of Cancer and Nutrition-Norfolk may involve diet-gene interactions. Cancer Epidemiol Biomarkers Prev. 2005 Jan;14(1):213-20.

331. Cherian G. Metabolic and cardiovascular diseases in poultry: role of dietary lipids. Poult Sci. 2007 May;86(5):1012-6.

332. Menéndez R, Más R, Pérez Y, et al. In Vitro effect of D-004, a lipid extract of the ground fruits of the Cuban royal palm (Roystonea regia), on rat microsomal lipid peroxidation. Phytother Res. 2007 Jan;21(1):89-95.

333. Schweizer S, von Brocke AF, Boden SE, et al. Workup-dependent formation of 5-lipoxygenase inhibitory boswellic acid analogues. J Nat Prod. 2000 Aug;63(8):1058-61.

334. Schweizer S, Eichele K, Ammon HP, et al. 3-Acetoxy group of genuine AKBA (acetyl-11-keto-beta-boswellic acid) is alpha-configurated. Planta Med. 2000b Dec;66(8):781-2.

335. Wallace JM. Nutritional and botanical modulation of the inflammatory cascade--eicosanoids, cyclooxygenases, and lipoxygenases--as an adjunct in cancer therapy. Integr Cancer Ther. 2002 Mar;1(1):7-37; discussion 37. Review.

336. Fong YK, Milani S, Djavan B. Role of phytotherapy in men with lower urinary tract symptoms. Curr Opin Urol. 2005 Jan;15(1):45-8. Review.

337. Gerber GS. Saw palmetto for the treatment of men with lower urinary tract symptoms. J Urol. 2000 May;163(5):1408-12.

338. Gansser D, Spiteller G. Plant constituents interfering with human sex hormone-binding globulin. Evaluation of a test method and its application to Urtica dioica root extracts. Z Naturforsch [C]. 1995 Jan-Feb;50(1-2):98-104.

339. Breza J, Dzurny O, Borowka A, et al. Efficacy and acceptability of tadenan (Pygeum africanum extract) in the treatment of benign prostatic hyperplasia (BPH): a multicentre trial in central Europe. Curr Med Res Opin. 1998;14(3):127-39.

340. Dreikorn K. The role of phytotherapy in treating lower urinary tract symptoms and benign prostatic hyperplasia. World J Urol. 2002 Apr;19(6):426-35.

341. PDR Health: http://www.pdrhealth.com/drug_info/nmdrugpro- files/nutsupdrugs/flo_0108.shtml. Accessed September 9, 2004.

342. Wilt TJ, Ishani A, Rutks I, et al. Phytotherapy for benign prostatic hyperplasia. Public Health Nutr. 2000 Dec;3(4A):459-72.

343. Kimura M, Kimura I, Nakase K. Micturition activity of pollen extract: contractile effects on bladder and inhibitory effects on urethral smooth muscle of mouse and pig. Planta Med. 1986 Apr;(2):148-51.

344. Pharmacometrics. 1986;31:1-11.

345. Folio Pharmacol Jpn. 1988;91:385-92.

346. Cui Y, Winton MI, Zhang ZF, et al. Dietary boron intake and prostate cancer risk. Oncol Rep. 2004 Apr;11(4):887-92.

347. Gallardo-Williams MT, Chapin RE, King PE, et al. Boron supplementation inhibits the growth and local expression of IGF-1 in human prostate adenocarcinoma (LNCaP) tumors in nude mice. Toxicol Pathol. 2004 Jan-Feb;32(1):73-8.

348.Ansari MS, Gupta NP. A comparison of lycopene and orchidectomy vs orchidectomy alone in the management of advanced prostate cancer. BJU Int. 2003 Sep;92(4):375-8; discussion 378. Erratum in: BJU Int. 2004 Mar;93(4):655.

349. Kim L, Rao AV, Rao LG. Effect of lycopene on prostate LNCaP cancer cells in culture. J Med Food. 2002 Winter;5(4):181-7.

350. Kucuk O, Sarkar FH, Djuric Z, et al. Effects of lycopene supplementation in patients with localized prostate cancer. Exp Biol Med (Maywood). 2002 Nov;227(10):881-5.

351.Vogt TM, Mayne ST, Graubard BI et al. Serum lycopene, other serum carotenoids, and risk of prostate cancer in US Blacks and Whites. Am J Epidemiol. 2002 Jun 1;155(11):1023-32.

352.Giovannucci E, Rimm EB, Liu Y. A prospective study of tomato products, lycopene, and prostate cancer risk. J Natl Cancer Inst. 2002 Mar 6;94(5):391-8.

Advanced Natural Prostate Formula with 5-Loxin®

*These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent any disease.

The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem. You should not stop taking any medication without first consulting your physician.