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Recommendation Number 10:

Super Booster Softgels with Advanced K2 Complex

DOSAGE: 1 softgel per day with a meal.

Filling In The Missing Gaps In Multivitamin Supplements

In spite of all the scientific validation surrounding the health benefits of various nutrients, many people fail to include them in their daily supplement regimen because they do not want to take so many individual pills. This problem has been solved with Life Extension® Super Booster, a softgel that includes a multitude of health-promoting nutrients with the convenience of one-per-day dosing. Super Booster contains nutrients that cannot fit into dry-based formulas like the Life Extension Mix™ formula (Recommendation #1 of the Top Ten Steps to Optimal Health).

Included in this potent, multi-nutrient formula are the most biologically active forms of vitamin K2 (known as menaquinone-4 and menaquinone-7). Human studies show that vitamin K2 is absorbed up to ten times more effectively than K1.1 Vitamin K2 also remains biologically active in the body far longer than K1. For instance, K1 is rapidly cleared by the liver within 8 hours, whereas measurable levels of K2 (as MK-7) have been detected 72 hours after ingestion. Because it is not metabolized quickly by the liver, only small amounts of vitamin K2 are needed to maintain optimal gamma-carboxylation status of Gla-proteins such as osteocalcin (in bone) and matrix-Gla protein (in the arterial vessel wall). These proteins direct calcium into the bones and prevent calcium precipitation in the arterial wall.2

Super Booster has been upgraded to provide even higher doses of menaquinone-7 in addition to vitamin K1 and MK-4.

Super Booster functions as the perfect complementary supplement because it contains nutrients that cannot fit into the tightly packed dry powder formula, along with nutrients that only come in an oil-base, and therefore require a softgel cap to contain them. Super Booster also contains nutrients with health benefits so well-documented that people often want to take higher amounts than what is provided in their daily multivitamin.

Just one softgel of Super Booster Softgels provides critically important nutrients such as gamma tocopherol that are lacking in most multi-nutrient formulas. Scientists have shown that people supplementing with the alpha tocopherol form of vitamin E should also consume gamma tocopherol. The reason is because alpha tocopherol displaces gamma tocopherol in the body, which may result in a lack of protection against certain types of free radicals.

Augmenting The Effects Of Gamma Tocopherol In Multi Vitamins

One problem with gamma tocopherol is that relatively small amounts are delivered to where it is often most needed. Super Booster provides 20 mg of sesame lignan extract to augment the dissemination of gamma tocopherol to cells throughout the body.

In human and animal studies, administration of sesame lignans increases tissue and serum levels of all vitamin E analogs, including gamma and alpha tocopherol.3

Of particular interest are studies showing that sesame lignans elevate gamma tocopherol levels quite dramatically.4 This is critical because gamma tocopherol, but not alpha tocopherol, quenches reactive nitrogen species, such as the peroxynitrite radical, which we know plays a major role in the development of cardiovascular problems.

The reason it is so difficult to raise gamma tocopherol levels in human tissues and serum is due to two forces that are constantly at work to defeat it. The only carrier protein that transports vitamin E from the liver to the tissues, alpha tocopherol carrier protein, is highly selective in transporting alpha tocopherol in a 11-to-1 ratio to gamma tocopherol.5

This means relatively little gamma tocopherol ends up in the cell membranes compared to alpha tocopherol. Studies have shown that adding sesame to a rat diet increased vitamin E alpha serum levels 40%, and gamma tocopherol levels up to about 500%,4 while lowering a measurement of free radical-induced damage (thiobarbituric reactive substances) by 82.8%.6 Another recent human study showed a single dose of sesame oil, containing 136 mg sesame lignans (sesamin and sesamolin), reduces the urinary excretion of co-administered gamma tocopherol in humans.7

Because of the importance of obtaining the gamma fraction of vitamin E, most Life Extension members who take the Two-Per-Day Tablets or Life Extension Mix™ (see Recommendation #1), also take one capsule of Super Booster Softgels.

So Much Potency in Just One Softgel: Folic Acid Supplements, B Complex Vitamins, And Much More

In order to reduce the cost and inconvenience of taking many different pills, Super Booster Softgels provide optimal doses of ginkgo extract, vitamin K1 and K2, chlorophyllin, lycopene, three forms of selenium, and other nutrients in just one capsule.

Ginkgo is the most popular flavonoid supplement in the world because of its multi-faceted effects of promoting healthy circulatory and neurological function.8

Vitamin K helps direct calcium to bones, while helping to maintain healthy arterial structure and elasticity.9 Chlorophyllin is a nutrient used as protection against DNA gene mutation.10*

The effects of selenium in boosting glutathione and protecting healthy cell colonies are well-established.11 Most people don’t know that the scientific literature reveals that there are several different forms of selenium that provide the diverse biological benefits attributed to this mineral. Super Booster provides selenomethionine, sodium selenate, and Se-methylselenocysteine.

Lycopene continues to impress scientists as the red carotenoid that inhibits LDL oxidation and also protects DNA gene integrity.12-14

Save Money with the Multi Vitamin Super Booster!

Super Booster Softgels saves you money by combining multiple ingredients into one formula. Listed on the next page are the ingredients contained in just one softgel of this advanced multinutrient formula.

Just one softgel of Super Booster Softgels provides:

Gamma E Mixed Tocopherol

359 mg

Typical distribution:

   Gamma Tocopherol

   Delta Tocopherol

   Alpha Tocopherol

   Beta Tocopherol

215-244.2 mg

88.9 to 125.7 mg

18 to 35.9 mg

0 to 7.2 mg

Ginkgo biloba extract

120 mg

Chlorophyllin

100 mg

Sesame seed lignan extract

20 mg

Lycopene

10 mg

Lutein

2 mg

Vitamin K1

1000 mcg

Vitamin K2 (MK-7)

100 mcg

Vitamin K2 (MK-4)

1000 mcg

Selenium

200 mcg

Vitamin B12

300 mcg

Vitamin C

90 mg

Ascorbyl Palmitate

50 mg

Zinc

10 mg

Copper

0.2 mg

The cost of purchasing these ingredients individually greatly exceeds the price of Super Booster Softgels. For instance, the retail prices of the gamma E tocopherol, lycopene-lutein extracts, vitamin K, folic acid-B12, ginkgo extract, and chlorophyllin add up to over $100. By using Life Extension Super Booster, members save 70% as opposed to buying these ingredients separately. The retail price for a bottle of 60 softgels is $42.00. If a member of the Life Extension Foundation buys four bottles, the price is reduced to only $28.50 per bottle.

Since most of these ingredients are fat-soluble, Super Booster Softgels should be taken with the heaviest meal of the day. Because the largest meal of the day often contains the most dietary mutagens, it is appropriate to consume the chlorophyllin contained in Super Booster at this time.

Note: Those individuals currently taking anticoagulants like Coumadin® (warfarin) should consult with their personal physician before taking supplemental vitamin K. Those with Wilson’s disease should not take chlorophyllin supplements. The Life Extension Booster formula (without vitamin K and chlorophyllin) is still available.

More Info on Super Booster Softgels with Advanced K2 Complex

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Super Booster Softgels, Vitamin K2, Multivitamin Supplements
Order Supplements Online
Filling In The Missing Gaps With Vitamin K2 And More
Top Ten Nutritional Supplements
1: Multivitamins and Minerals
(Life Extension Mix™)
2: Omega-3 Fatty Acids (Fish Oil)
3: Coenzyme Q10 (CoQ10)
4: Mitochondrial Function (MEO)
5: Hormone Balance (DHEA)
6: Brain Cell Function (Cognitex)
7: Bone Health (for women and men)
7a: Prostate Health (for men only)
8: Neural and Hepatic Health (SAMe)
9: Cardiovascular Health (Aspirin)
10: Vitamin K, Gamma Tocopherol (Super Booster Softgels)

References

1. Schurgers LJ, Vermeer C. Determination of phylloquinone and menaquinones in food. Effect of food matrix on circulating vitamin K concentrations. Haemostasis. 2000 Nov-Dec;30(6):298-307.

2. Schurgers LJ, Dissel PE, Spronk HM, et al. Role of vitamin K and vitamin K-dependent proteins in vascular calcification. Z Kardiol. 2001;90 Suppl 3:57-63.

3. Yamashita K, Ikeda S, et al. Effect of sesaminol on plasma and tissue alpha-tocopherol and alpha tocotrienol concentrations in rats fed a vitamin E concentrate rich in tocotrienols. Lipids. 2002 Apr;37(4):351-8.

4. Ikeda S, Tohyama T, et al. Dietary sesame seeds and its lignans inhibit 2,7,8-trimethyl-2(2’-carboxyethyl)-6-hydrooxychroman excretion into urine of rats fed gamma-tocopherol. J Nutr. 2002 May;132(5):961-6.

5. Hosomi A, Arita M, Sato Y, et al. Affinity for alpha-tocopherol transfer protein as a determinant of the biological activities of vitamin E analogs. FEBS Lett. 1997 Jun 2;409(1):105-8.

6. Kang M, Naito M, et al. Mode of Action of Sesame Lignans in Protecting Low-Density Lipoprotein against Oxidative Damage in Vitro. Life Sci. 2000 66(2):161-71.

7. Frank J, Kamal-Eldin A, Traber MG. Consumption of sesame oil muffins decreases the urinary excretion of gamma-tocopherol metabolites in humans. Ann N Y Acad Sci. 2004 Dec;1031:365-7.

8. [No authors listed]Ginkgo biloba. Altern Med Rev. 1998 Feb;3(1):54-7.

9. Vermeer C, Shearer MJ, et al. Beyond deficiency: Potential benefits of increased intakes of vitamin K for bone and vascular health. Eur J Nutr. 2004 Dec;43(6):325-35.

10. Tajmir-Riahi HA, Neault JF, et al. DNA adducts with chlorophyll and chlorophyllin as antimutagenic agents: synthesis, stability, and structural features. Methods Mol Biol. 2004;274:159-71.

11. Patrick L. Selenium biochemistry and cancer: A review of the literature. Altern Med Rev. 2004 Sep;9(3):239-58.

12. Ahuja KD, Ashton EL, et al. Effects of two lipid-lowering, carotenoid controlled diets on the oxidative modification of low-density lipoproteins in free-living humans. Clin Sci. 2003 Sep;105(3):355-61.

13. Fuhrman B, Volkova N, Rosenblat M, et al. Lycopene synergistically inhibits LDL oxidation in combination with vitamin E, glabridin, rosmarinic acid, carnosic acid, or garlic. Antioxid Redox Signal. 2000 Fall;2(3):491-506.

14. Scolastici C, Alves de Lima RO, Barbisan LF, et al. Lycopene activity against chemically induced DNA damage in Chinese hamster ovary cells. Toxicol In Vitro. 2007 Aug;21(5):840-5. Epub 2007 Jan 31.
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*These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent any disease. The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem. You should not stop taking any medication without first consulting your physician.