Winter Wellness™

60 capsules, Item# 01739

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  • Winter Wellness™
  • 60 capsules
  • Item Catalog Number: 01739

Every winter, human immune systems are overworked as they provide essential defense against seasonal challenges— especially the immune systems of the elderly and very young.1-4 A crucial part of this protection comes from the immune system’s production of new antibodies when the new winter season’s pathogens are first introduced, which boosts the body’s preparedness for upcoming challenges during peak winter outbreaks.5

In a remarkable discovery, the amino acids in Winter Wellness™ have been shown to work together to prime the immune system to optimize immune responsiveness.4,6-8 Taken daily, they support the host immune system’s primary defenders by enhancing the function of key immune cells to generate antibodies and naturally prime readiness—especially when taken at least two weeks prior to the first pre-season exposure to the winter’s new antigen challenges.4,6,7

L-theanine is a distinctive amino acid found almost exclusively in tea leaves.8 L-cystine is an amino acid synthesized by the body from the cysteine molecules found in many plant and animal food sources.9 Scientists have found that L-theanine and L-cystine have potent, complementary effects on immune responsiveness.6,7

Now combined in the next-generation, immune-supporting product Winter Wellness™, L-theanine and L-cystine promote the natural enhancement in responsiveness that follows pre-season antigen-exposure by:

  • Helping to enhance gamma delta T cells, ensuring an optimum state of readiness to respond through secretion of interleukin-2—a powerful immune regulator.6
  • Supporting the release of immune system proteins that coordinate interactions between T cells and antibodies— further promoting immune responsiveness.10
  • Contributing to the synthesis of glutathione—a potent endogenous antioxidant—that has a marked effect on immune function.4,11

Scientific data supports that when these potent amino acids are used together, they support an enhanced post-exposure immune response.4,6-8

A double-blind, placebo-controlled clinical trial on humans found that the two amino acids in Winter Wellness™ significantly promoted antigen responsiveness.6 A group of nursing home residents over age 65 were co-administered 280 milligrams of L-theanine and 700 milligrams of L-cystine once daily for 14 days. After controlled exposure to several new winter antigens on the 15th day, the scientists found that for certain groups, supplementation resulted in an increased rate of seroconversion—the point at which the immune system first develops antibody protection against a microorganism as a result of new antigen exposure.6

Winter Wellness™ powerfully primes the immune system against seasonal winter challenges.

1. Q Rev Biol. 1996 Dec;71(4):511-48.
2. Cell Immunol. 2000 Mar 15;200(2):105-15.
3. Available at: infantcare.htm. Accessed September 12, 2013.
4. J Vet Med Sci. 2010 Feb;72(2):157-65.
5. Available at: /res/pdf/9780815342434_ch02.pdf. Accessed September 16, 2013.
6. Geriatr Gerontol Int. 2008 Dec;8(4):243-50.
7. J Amino Acids. 2010;2010:307475.
8. Nutr Rev. 2008 Feb;66(2):96-102.
9. Int J Angiol. 2010 Spring; 19(1):e7–e20.
10. Immunity. 1999;11:57-65.
11. J Vet Med Sci. 2007 Dec;69(12):1263-70.
Supplement Facts

Serving Size 2 capsule

Servings Per Container 30

Amount Per Serving


700 mg


280 mg

Other ingredients: vegetable cellulose (capsule), dicalcium phosphate, microcrystalline cellulose, silica, vegetable stearate.

Dosage and Use
  • Take two capsules daily with or without food, or as recommended by a healthcare practitioner.