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Abstracts

Superoxide Dismutase Overview

A metal-containing antioxidant enzyme that reduces potentially harmful free radicals of oxygen formed during normal metabolic cell processes to oxygen and hydrogen peroxide -- abbreviation SOD. Therefore SOD reduces oxidative stress and can play a key role in moderating the ageing process.

Single point mutations in SOD are associated with the development of a form of motor neuron disease. SOD is used to treat arthritis and other joint disorders, prevent side effects of cancer treatment, prostate problems, and Peyronie's disease. It is also used as an antioxidant. SOD is sometimes used to treat amyotrophic lateral sclerosis (ALS), prevent injury to transplant organs during surgery, and to prevent lung problems in premature infants

Dosage: It is thought to be only available by injection and administration can produce allergic reactions. However, sublingual and cream forms of SOD are now being used.

(Source: http://www.nlm.nih.gov/medlineplus/mplusdictionary.html and http://www.genesishealth.com/micromedex/altmedgen/ame0331.aspx)

Research Overview

Superoxide dismutase research reveals the following:
1. Reduces ishemia reperfusion injury
2. Protects against ishemic brain injury
3. Helps heal corneal ulcers
4. Reduces brain swelling after traumatic brain injury
5. Protects organs following burn injury
6. Speeds healing following burn injury
7. Reduces long term damage from burn injury
8. Is effective in treating inflammatory diseases
9. Prevents lipid peroxidation
10. Prevents smoke inhalation injury
11. Protects from radiation injury
12. Reduces periodontal inflammation
13. Prevents side effects from cancer drugs
14. Treats inflammation from arthritis
15. Reduces inflammatory bowel disease
16. Is an effective antioxidant

Superoxide Dismutase Citations (61)