May 9, 2000
National Academy of Sciences References
001-135 136-270 271-410 411-555 1. Kolonel LN, et al. Multiethnic studies of diet, nutrition, and cancer in Hawaii. Princess Takamatsu Symp 1985;16:29-40. 2. Verhoeven DT, et al. Vitamins C and E, retinol, beta-carotene and dietary fibre in relation to breast cancer risk: a prospective cohort study. Br J Cancer 1997;75(1):149-55. 3. Kurbacher CM, et al. Ascorbic acid (vitamin C) improves the antineoplastic activity of doxorubicin, cisplatin, and paclitaxel in human breast carcinoma cells in vitro. Cancer Lett 1996 Jun 5;103(2):183-9. 4. Ramaswamy G, et al. Serum carotene, vitamin A, and vitamin C levels in breast cancer and cancer of the uterine cervix. Nutr Cancer 1996;25(2):173-7. 5. Guo WD, et al. Diet, serum markers and breast cancer mortality in China. Jpn J Cancer Res 1994 Jun;85(6):572-7. 6. Rohan TE, et al. Dietary factors and survival from breast cancer. Nutr Cancer 1993;20(2):167-77. 7. Cameron E, Pauling L. Supplemental ascorbate in the supportive treatment of cancer: Prolongation of survival times in terminal human cancer. Proc Natl Acad Sci U S A 1976 Oct;73(10):3685-9. 8. Venkatesan K, et al. Effect of ascorbic acid on blood levels of DDS. Lepr India 1979 Oct;51(4):511-4. 9. Fontana M . Vitamin C (ascorbic acid): clinical implications for oral health--a literature review. Compendium 1994 Jul;15(7):916, 918, 920 passim; quiz 930. 10. Aurer-Kozelj J, et al. The effect of ascorbic acid supplementation on periodontal tissue ultrastructure in subjects with progressive periodontitis. Int J Vitam Nutr Res 1982;52(3):333-41. 11. Trykowsky J, et al. [The use of toothpaste with vitamin C in treating periodontitis]. Stomatologiia (Mosk) 1994 Jan-Mar;73(1):11-3. 12. Holmes LG. Effects of smoking and/or vitamin C on crevicular fluid flow in clinically healthy gingiva. Quintessence Int 1990 Mar;21(3):191-5. 13. Muzzarelli R, et al. Reconstruction of parodontal tissue with chitosan. Biomaterials 1989 Nov;10(9):598-603. 14. Rubinoff AB, et al. Vitamin C and oral health. J Can Dent Assoc 1989 Sep;55(9):705-7. 15. Melnick SL, et al. A case-control study of plasma ascorbate and acute necrotizing ulcerative gingivitis. J Dent Res 1988 May;67(5):855-60. 16. Jacob RA, et al. Experimental vitamin C depletion and supplementation in young men. Nutrient interactions and dental health effects. Ann N Y Acad Sci 1987;498:333-46. 17. Leggott PJ, et al. The effect of controlled ascorbic acid depletion and supplementation on periodontal health. J Periodontol 1986 Aug;57(8):480-5. 18. Ellis CN, et al. Scurvy. A case caused by peculiar dietary habits. Arch Dermatol1984 Sep;120(9):1212-4. 19. Khan PK, et al. Vitamin C mediated amelioration of pesticide genotoxicity in murine spermatocytes. Cytobios 1994;80(323):199-204. 20.Sarma L, et al. Protective effects of vitamins C and E against gamma-ray-induced chromosomal damage in mouse. Int J Radiat Biol 1993 Jun;63(6):759-64. 21.Dreosti I, et al. Antioxidants and UV-induced genotoxicity. Res Commun Chem Pathol Pharmacol 1992 Feb;75(2):251-4. 22. Trizna Z, et al. Effects of N-acetyl-L-cysteine and ascorbic acid on mutagen-induced chromosomal sensitivity in patients with head and neck cancers. Am J Surg 1991 Oct;162(4):294-8. 23. Pohl H, et al. Vitamin C intake influences the bleomycin-induced chromosome damage assay: implications for detection of cancer susceptibility and chromosome breakage syndromes. Mutat Res 1989 Oct;224(2):247-52. 24. Pohl H, et al. Vitamin C intake influences the bleomycin-induced chromosome damage assay: implications for detection of cancer susceptibility and chromosome breakage syndromes. 1989 Mutat Res Oct;224(2):247-52. 25. Gebhart E, et al. The action of anticlastogens in human lymphocyte cultures and their modification by rat-liver S9 mix. II. Studies with vitamins C and E. Mutat Res 1985 Mar;149(1):83-94. 26. Antunes LM, et al. Effects of high doses of vitamins C and E against doxorubicin-induced chromosomal damage in Wistar rat bone marrow cells. Mutat Res 1998 Nov 9;419(1-3):137-43. 27. Tavares DC, et al. Protective effects of the amino acid glutamine and of ascorbic acid against chromosomal damage induced by doxorubicin in mammalian cells. Teratog Carcinog Mutagen 1998;18(4):153-61. 28. Cozzi R, et al. Ascorbic acid and beta-carotene as modulators of oxidative damage. Carcinogenesis 1997 Jan;18(1):223-8. 29. Makedonov GP, et al. [The anticlastogenic effect of ascorbic acid in relation to the damages inducedin human lymphocytes by the photomutagenic action of 8-methoxypsoralen and by ammonium molybdate]. Radiats Biol Radioecol 1995 Sep-Oct;35(5):726-9. 30. Makedonov GP, et al. [The anticlastogenic effect of ascorbic acid in relation to the damages induced in human lymphocytes by the photomutagenic action of 8-methoxypsoralen and by ammonium molybdate]. [Article in Russian] Radiats Biol Radioecol 1995 Sep-Oct;35(5):726-9. 31.Anderson D, et al. The effect of antioxidants on bleomycin treatment in in vitro and in vivo genotoxicity assays. Mutat Res 1995 Jun;329(1):37-47. 32. Piyathilake CJ, et al. Cigarette smoking, intracellular vitamin deficiency, and occurrence of micronuclei in epithelial cells of the buccal mucosa. Cancer Epidemiol Biomarkers Prev 1995 Oct-Nov;4(7):751-8. 33. Bilgrami KS, et al. Cumulative effect of T-2 toxin and vitamin C on chromosomal abnormalities in the bone marrow cells of mice (Mus musculus). Cytobios 1995;81(326):171-4. 34.Antunes LM, et al. Protection and induction of chromosomal damage by vitamin C in human lymphocyte cultures. Teratog Carcinog Mutagen 1999;19(1):53-9. 35. Konturek PC, et al. Helicobacter pylori associated gastric pathology. J Physiol Pharmacol 1999 Dec;50(5):695-710. 36. Bennedsen M, et al. Treatment of H. pylori infected mice with antioxidant astaxanthin reduces gastric inflammation, bacterial load and modulates cytokine release by splenocytes. Immunol Lett 1999 Dec 1;70(3):185-9. 37. Fraser AG, et al. Gastric juice ascorbic acid is related to Helicobacter pylori infection but not ethnicity.J Gastroenterol Hepatol 1999 Nov;14(11):1070-3. 38. Rokkas T, et al. Relationship of Helicobacter pylori CagA(+) status to gastric juice vitamin C levels. Eur J Clin Invest 1999 Jan;29(1):56-62. 39. Jarosz M, et al. Effects of high dose vitamin C treatment on Helicobacter pylori infection and total vitamin C concentration in gastric juice. Eur J Cancer Prev 1998 Dec;7(6):449-54. 40. Zhang ZW, et al. The relation between gastric vitamin C concentrations, mucosal histology, and CagA seropositivity in the human stomach. Gut 1998 Sep;43(3):322-6. 41. Drake IM, et al. Ascorbic acid may protect against human gastric cancer byscavenging mucosal oxygen radicals. Carcinogenesis 1996 Mar;17(3):559-62. 42. Retsky KL, et al. Vitamin C prevents metal ion-dependent initiation and propagation of lipid peroxidation in human low-density lipoprotein. Biochim Biophys Acta 1995 Aug 3;1257(3):279-87. 43. Scaccini C, et al. A critical assessment of the effects of aminoguanidine and ascorbate on the oxidative modification of LDL: evidence for interference with some assays of lipoprotein oxidation by aminoguanidine.J Lipid Res 1994 Jun;35(6):1085-92. 44. Scaccini C, et al. A critical assessment of the effects of aminoguanidine and ascorbate on the oxidative modification of LDL: evidence for interference with some assays of lipoprotein oxidation by aminoguanidine. J Lipid Res 1994 Jun;35(6):1085-92. 45. Azenabor AA, et al. Generation of reactive oxygen species and formation and membrane lipid peroxides in cells infected with Chlamydia trachomatis. Int J Infect Dis 2000;4(1):46-50. 46. Shilotri PG, et al. Effect of mega doses of vitamin C on bactericidal ativity of leukocytes. Am J Clin Nutr 1977 Jul;30(7):1077-81. 47. Anderson R. Effects of ascorbate on normal and abnormal leucocyte functions. Nutr Res Suppl 1982;23:23-34. 48. Corberand J, et al. Malignant external otitis and polymorphonuclear leukocyte migration impairment. Improvement with ascorbic acid. Arch Otolaryngol 1982 Feb;108(2):122-4. 49. Anderson R, et al . Effects of ascorbate on leucocytes: Part III. In vitro and in vivo stimulation of abnormal neutrophil motility by ascorbate. Arch Otolaryngol 1982 Feb;108(2):122-4S Afr Med J 1979 Sep 8;56(11):429-33. 50. Boura P, et al . Monocyte locomotion in anergic chronic brucellosis patients: the in vivo effect of ascorbic acid. Immunopharmacol Immunotoxicol 1989;11(1):119-29. 51. Foster CS, et al. Ascorbate therapy in impaired neutrophil and monocyte chemotaxis. With atopy, hyperimmunoglobulinemia E, and recurrent infection. Arch Ophthalmol 1978 Nov;96(11):2069-72. 52. Rebora A, et al. Repeated staphylococcal pyoderma in two siblings with defective neutrophil bacterial killing. Dermatologica 1980;160(2):106-12. 53. Patrone F, et al. Disorders of neutrophil function in children with recurrent pyogenic infections. Med Microbiol Immunol (Berl) 1982;171(2):113-22. 54. Patrone F, et al. Effects of ascorbic acid on neutrophil function. Studies on normal and chronic granulomatous disease neutrophils. Acta Vitaminol Enzymol 1982;4(1-2):163-8. 55. Rebora A, et al. Neutrophil dysfunction and repeated infections: influence of levamisole and ascorbic acid. Br J Dermatol 1980 Jan;102(1):49-56. 56. de la Fuente M, et al. Immune function in aged women is improved by ingestion of vitamins C and E. Can J Physiol Pharmacol 1998 Apr;76(4):373-80. 57. Levy R, et al. Successful treatment of a patient with recurrent furunculosis by vitamin C: improvement of clinical course and of impaired neutrophil functions. Int J Dermatol 1993 Nov;32(11):832-4. 58. Anderson R. Ascorbate-mediated stimulation of neutrophil motility and lymphocyte transformation by inhibition of the peroxidase/H2O2/halide system in vitro and in vivo. Am J Clin Nutr 1981 Sep;34(9):1906-11. 59. Ferrandez MD, et al. Effects in vitro of several antioxidants on the natural killer function of aging mice. Exp Gerontol 1999 Aug;34(5):675-85. 60. Heuser G, et al. Enhancement of natural killer cell activity and T and B cell function by buffered vitamin C in patients exposed to toxic chemicals: the role of protein kinase-C. Immunopharmacol Immunotoxicol 1997 Aug;19(3):291-312. 61. Hurlimann R, et al. [Scurvy--a mistakenly forgotten disease]. [Article in German] Schweiz Med Wochenschr 1994 Aug 9;124(31-32):1373-80. 62. Ghorbani AJ, et al. Scurvy. J Am Acad Dermatol 1994 May;30(5 Pt 2):881-3. 63. Valkonen MM, et al. Vitamin C prevents the acute atherogenic effects of passive smoking. Free Radic Biol Med 2000 Feb 1;28(3):428-36. 64. Galley HF, et al. Combination oral antioxidant supplementation reduces blood pressure. Clin Sci (Colch) 1997 Apr;92(4):361-5. 65. Gokce N, et al.Long-term ascorbic acid administration reverses endothelial vasomotor dysfunction in patients with coronary artery disease. Circulation 1999 Jun 29;99(25):3234-40. 66. Chambers JC, et al.Demonstration of rapid onset vascular endothelial dysfunction after hyperhomocysteinemia: an effect reversible with vitamin c therapy. Circulation 1999 Mar 9;99(9):1156-60. 67. Wilkinson IB, Megson IL, et al. Oral vitamin C reduces arterial stiffness and platelet aggregation in humans. J Cardiovasc Pharmacol 1999 Nov;34(5):690-3. 68. Jeserich M, et al. Vitamin C improves endothelial function of epicardial coronary arteries in patients with hypercholesterolaemia or essential hypertension--assessed by cold pressor testing. Eur Heart J 1999 Nov;20(22):1676-80. 69. Frei B . On the role of vitamin C and other antioxidants in atherogenesis and vascular dysfunction. Proc Soc Exp Biol Med 1999 Dec;222(3):196-204. 70. Fuller CJ, et al. Effect of ascorbate supplementation on low density lipoprotein oxidation in smokers. Atherosclerosis 1996 Jan 26;119(2):139-50. 71. Kuusi T . Vitamin C prevents the acute atherogenic effects of passive smoking.Valkonen MM, Free Radic Biol Med 2000 Feb 1;28(3):428-36. 72. Zhang J, et al. A single high dose of vitamin C counteracts the acute negative effect on microcirculation induced by smoking a cigarette. Microvasc Res 1999 Nov;58(3):305-11. 73. Purkayastha SS, et al. Effect of vitamin C and E in modulating peripheral vascular response to local cold stimulus in man at high altitude. Jpn J Physiol 1999 Apr;49(2):159-67. 74. Chamiec T, et al.Effects of antioxidant vitamins C and E on signal-averaged electrocardiogram in acute myocardial infarction. Am J Cardiol 1996 Feb 1; 77(4):237-41. 75. Gatto LM, et al. Ascorbic acid induces a favorable lipoprotein profile in women. J Am Coll Nutr 1996 Apr;15(2):154-8. 76. Singh RB, et al . Usefulness of antioxidant vitamins in suspected acute myocardial infarction (the Indian experiment of infarct survival-3). Am J Cardiol 1996 Feb 1;77(4):232-6. 77. Munoz JA, et al . Effect of VITAMIN C on lipoproteins in healthy adults. Ann Med Interne (Paris) 1994;145(1):13-9. 78. Tomoda H, et al. Possible prevention of postangioplasty restenosis by Ascorbic acid. Am J Cardiol 1996 Dec 1;78(11):1284-6. 79. Laskowski H, et al. Mortality and clinical course of patients with acute myocardial infarction treated with streptokinase and antioxidants: mannitol and Ascorbic acid. Int J Cardiol 1995 Mar 3;48(3):235-7. 80. Eriksson J, et al. Magnesium and Ascorbic acid supplementation in diabetes mellitus. Ann Nutr Metab 1995;39(4):217-23. 81. Cerna O,et al.Plasma lipids, lipoproteins and atherogenic index in men and women administered vitamin c. Cor Vasa 1992;34(3):246-54. 82. Barta E, et al.Protective effect of alpha-tocopherol and L-ascorbic acid against the ischemic-reperfusion injury in patients during open-heart surgery. Bratisl Lek Listy 1991 Mar-Apr;92(3-4):174-83. 83. Salonen JT,et al. Effects of antioxidant supplementation on platelet function: a randomized pair-matched, placebo-controlled, double-blind trial in men with low antioxidant status. Am J Clin Nutr 1991 May;53(5):1222-9. 84. Mayer-Davis EJ, et al. Vitamin c intake and cardiovascular disease risk factors in persons with non-insulin-dependent diabetes mellitus. From the Insulin Resistanc Atherosclerosis Study and the San Luis Valley Diabetes Study. rev Med 1997 May-Jun;26(3):277-83. 85. Bostom AG, et al.The effect of high-dose ascorbate supplementation on plasma lipoprotein(a) levels in patients with premature coronary heart disease. Pharmacotherapy 1995 Jul-Aug;15(4):458-64. 86. Westhuyzen J, et al.Effect of preoperative supplementation with alpha-tocopherol and ascorbic acid on myocardial injury in patients undergoing cardiac operations. J Thorac Cardiovasc Surg 1997 May;113(5):942-8. 87. Tanaka H, et al.Reduction of resuscitation fluid volumes in severely burned patients using ascorbic acid administration: a randomized, prospective study. Arch Surg 2000 Mar;135(3):326-31. 88. Kodama N, et al. Cisternal irrigation therapy with urokinase and ascorbic acid for prevention of vasospasm after aneurysmal subarachnoid hemorrhage. Outcome in 217 patients. Surg Neurol 2000 Feb;53(2):110-7; discussion 117-8. 89. Sinclair S, et al. Male infertility: nutritional and environmental considerations. Altern Med Rev 2000 Feb;5(1):28-38. 90. van Rooij J, et al. Oral vitamins C and E as additional treatment in patients with acute anterior uveitis: a randomised double masked study in 145 patients. Br J Ophthalmol 1999 Nov;83(11):1277-82. 91. Zollinger PE, et al. Effect of vitamin C on frequency of reflex sympathetic dystrophy in wrist fractures:a randomised trial. Lancet 1999 Dec 11;354 (9195):2025-8. 92. Gorton HC, et al. The effectiveness of vitamin C in preventing and relieving the symptoms of virus-induced respiratory infections. J Manipulative Physiol Ther 1999 Oct;22(8):530-3. 93. Vermeer IT, et al. Effect of ascorbic acid and green tea on endogenous formation of N-nitrosodimethylamine and N-nitrosopiperidine in humans. Mutat Res 1999 Jul 16;428(1-2):353-61. 94. Reinhold U, et al. Treatment of progressive pigmented purpura with oral bioflavonoids and ascorbic acid: an open pilot study in 3 patients. J Am Acad Dermatol 1999 Aug;41(2 Pt 1):207-8. 95. Hemila H. Vitamin C supplementation and common cold symptoms: factors affecting the magnitude of the benefit. Med Hypotheses 1999 Feb;52(2):171-8. 96. McAuliffe AV, et al. Administration of ascorbic acid and an aldose reductase inhibitor (tolrestat) in diabetes: effect on urinary albumin excretion. Nephron 1998 Nov;80(3):277-84. 97. de la Fuente M, et al. Immune function in aged women is improved by ingestion of vitamins C and E. Can J Physiol Pharmacol 1998 Apr;76(4):373-80. 98. Allard JP, et al. Effects of vitamin E and C supplementation on oxidative stress and viral load in HIV-infected subjects AIDS 1998 Sep 10;12(13):1653. 99. Eberlein-Konig B, et al. Phototoxic lysis of erythrocytes from humans is reduced after oral intake of Ascorbic acid and d-alpha-tocopherol. Photodermatol Photoimmunol Photomed 1997 Oct-Dec;13(5-6):173-7. 100. Alessio HM, et al.Exercise-induced oxidative stress before and after VITAMIN C supplementation. Int J Sport Nutr 1997 Mar;7(1):1-9. 101. Schwille PO, et al. Postprandial hyperinsulinaemia, insulin resistance and inappropriately high phosphaturia are features of younger males with idiopathic calcium urolithiasis: attenuation by Ascorbic acid supplementation of a test meal. Urol Res 1997;25(1):49-58. 102. Hemila H, et al. Vitamin C intake and susceptibility to the common cold. Br J Nutr 1997 Jan;77(1):59-72. 103. Gustafsson U, et al. The effect of VITAMIN C in high doses on plasma and biliary lipid composition in patients with cholesterol gallstones: prolongation of the nucleation time. Eur J Clin Invest 1997 May;27(5):387-91. 104. Jeng KC, et al.Supplementation with vitamins C and E enhances cytokine production by peripheral blood mononuclear cells in healthy adults. Am J Clin Nutr 1996 Dec;64(6):960-5. 105. McAlindon ME, et al. Effect of allopurinol, sulphasalazine, and VITAMIN C on aspirin induced gastroduodenal injury in human volunteers. Gut 1996 Apr;38(4):518-24. 106. Boffa MJ, et al. A double-blind, placebo-controlled, crossover trial of oral VITAMIN C in erythropoietic protoporphyria. Photodermatol Photoimmunol Photomed 1996 Feb;12(1):27-30. 107. Lonnrot K, et al. The effect of ascorbate and ubiquinone supplementation on plasma and CSF total antioxidant capacity. Free Radic Biol Med 1996;21(2):211-7. 108. Nadgrodkiewicz K , et al. [The effect of intravenous Ascorbic acid on urinary 17-hydroxysteroid excretion at an early stage of cerebral stroke]. Neurol Neurochir Pol 1996 Jan-Feb;30(1):49-56. 109. Wang H, et al. Experimental and clinical studies on the reduction of erythrocyte sorbitol-glucose ratios by Ascorbic acid in diabetes mellitus. Diabetes Res Clin Pract 1995 Apr;28(1):1-8. 110. Sharma DC, et al. .Correction of anemia and iron deficiency in vegetarians by administration of Ascorbic acid. Indian J Physiol Pharmacol 1995 Oct;39(4):403-6. 111. Paolisso G, et al. Metabolic benefits deriving from chronic VITAMIN C supplementation in aged non-insulin dependent diabetics. J Am Coll Nutr 1995 Aug;14(4):387-92. 112. Gastaldello K,et al.Resistance to erythropoietin in iron-overloaded haemodialysis patients can be overcome by Ascorbic acid administration. Nephrol Dial Transplant 1995;10 Suppl 6:44-7. 113. Skin wound healing process. A double-blind, prospective and randomized trial. Eur Surg Res 1995;27(3):158-66. 114. Wang H, Zhang ZB, et al. [Reduction of erythrocyte sorbitol by Ascorbic acid in patients with diabetes mellitus]. Chung Hua I Hsueh Tsa Chih 1994 Sep;74(9):548-51, 583. 115. Herbaczynska-Cedro K, et al. Inhibitory effect of vitamins C and E on the oxygen free radical production in human polymorphonuclear leucocytes. Eur J Clin Invest 1994 May;24(5):316-9. 116. Cunningham JJ, et al. VITAMIN C: an aldose reductase inhibitor that normalizes erythrocyte sorbitol in insulin-dependent diabetes mellitus. J Am Coll Nutr 1994 Aug;13(4):344-50. 117. Kataoka A, et al. [Intermittent high-dose VITAMIN C therapy in patients with HTLV-I-associated myelopathy]. Rinsho Shinkeigaku 1993 Mar;33(3):282-8. 118. Dumitrescu C, et al. Effect of VITAMIN C administration on the ratio between the pro- and antioxidative factors. Rom J Endocrinol 1993;31(1-2):81-4. 119. Karduss Urueta A, et al. [Results of the treatment of chronic idiopathic thrombocytopenic purpura with Ascorbic acid]. Gac Med Mex 1993 Jan-Feb;129(1):23-5. 120. Dawson EB, et al. Effect of Ascorbic acid supplementation on the sperm quality of smokers. Fertil Steril 1992 Nov;58(5):1034-9. 121. Triana Mantilla ME, et al. [The effect of VITAMIN C on the lipolytic activity in type-II diabetics with angiopathy]. [Article in Spanish] Angiologia 1991 Mar-Apr;43(2):77-81. 122. Reed PI, et al.Effect of Ascorbic acid on the intragastric environment in patients at increased risk of developing gastric cancer. IARC Sci Publ 1991;(105):139-42. 123. Beser E et al.The effects of short-term VITAMIN C on plasma bun, uric acid, cholesterol and triglyceride levels. Acta Med Hung 1991;48(1-2):73-8. 124. Bucca C, et al. Effect of VITAMIN C on histamine bronchial responsiveness of patients with allergic rhinitis. Ann Allergy 1990 Oct;65(4):311-4 Ann Allergy 1990 Oct;65(4):311-4. 125. Hunt JR, et al. Ascorbic acid: effect on ongoing iron absorption and status in iron-depleted young women. Am J Clin Nutr 1990 Apr;51(4):649-55. 126. Mai J, et al. High dose antioxidant supplementation to MS patients. Effects on glutathione peroxidase, clinical safety, and absorption of selenium. Biol Trace Elem Res 1990 Feb;24(2):109-17. 127. Mirvish SS, et al. Effect of ascorbic acid dose taken with a meal on nitrosoproline excretion in subjects ingesting nitrate and proline. Nutr Cancer 1998;31(2):106-10. 128. Seven A, et al. Biochemical evaluation of oxidative stress in propylthiouracil treated hyperthyroid patients. Effects of vitamin C supplementation. Clin Chem Lab Med 1998 Oct;36(10):767-70. 129.Heuser G, et al. Enhancement of natural killer cell activity and T and B cell function by buffered VITAMIN C in patients exposed to toxic chemicals: the role of protein kinase-C. Immunopharmacol Immunotoxicol 1997 Aug;19(3):291-312. 130. Liyanage C, et al. Iron absorption from a traditional Sri Lankan weaning food and the enhancing effect of Ascorbic acid in adult male volunteers. Ceylon Med J 1996 Dec;41(4):135-40. 131. Hunt C, et al. The clinical effects of VITAMIN Csupplementation in elderly hospitalised patients with acute respiratory infections. Int J Vitam Nutr Res 1994;64(3):212-9. 132. Johnston CS, et al. Megadose of VITAMIN C delays insulin response to a glucose challenge in normoglycemic adults. Am J Clin Nutr 1994 Nov;60(5):735-8. 133. Bednar C, et al. Nitrate and VITAMIN C from fruits and vegetables: impact of intake variations on nitrate and nitrite excretions of humans. Plant Foods Hum Nutr 1994 Jan;45(1):71-80. 134. Levin ED, et al. Clinical trials using Ascorbic acid aerosol to aid smoking cessation. Drug Alcohol Depend 1993 Oct;33(3):211-23. 135.Maxwell SR, et al. Changes in plasma antioxidant status during eccentric exercise and the effect of vitamin supplementation. Free Radic Res Commun 1993;19(3):191-202 .
1. Kolonel LN, et al. Multiethnic studies of diet, nutrition, and cancer in Hawaii. Princess Takamatsu Symp 1985;16:29-40.
2. Verhoeven DT, et al. Vitamins C and E, retinol, beta-carotene and dietary fibre in relation to breast cancer risk: a prospective cohort study. Br J Cancer 1997;75(1):149-55.
3. Kurbacher CM, et al. Ascorbic acid (vitamin C) improves the antineoplastic activity of doxorubicin, cisplatin, and paclitaxel in human breast carcinoma cells in vitro. Cancer Lett 1996 Jun 5;103(2):183-9.
4. Ramaswamy G, et al. Serum carotene, vitamin A, and vitamin C levels in breast cancer and cancer of the uterine cervix. Nutr Cancer 1996;25(2):173-7.
5. Guo WD, et al. Diet, serum markers and breast cancer mortality in China. Jpn J Cancer Res 1994 Jun;85(6):572-7.
6. Rohan TE, et al. Dietary factors and survival from breast cancer. Nutr Cancer 1993;20(2):167-77.
7. Cameron E, Pauling L. Supplemental ascorbate in the supportive treatment of cancer: Prolongation of survival times in terminal human cancer. Proc Natl Acad Sci U S A 1976 Oct;73(10):3685-9.
8. Venkatesan K, et al. Effect of ascorbic acid on blood levels of DDS. Lepr India 1979 Oct;51(4):511-4.
9. Fontana M . Vitamin C (ascorbic acid): clinical implications for oral health--a literature review. Compendium 1994 Jul;15(7):916, 918, 920 passim; quiz 930.
10. Aurer-Kozelj J, et al. The effect of ascorbic acid supplementation on periodontal tissue ultrastructure in subjects with progressive periodontitis. Int J Vitam Nutr Res 1982;52(3):333-41.
11. Trykowsky J, et al. [The use of toothpaste with vitamin C in treating periodontitis]. Stomatologiia (Mosk) 1994 Jan-Mar;73(1):11-3.
12. Holmes LG. Effects of smoking and/or vitamin C on crevicular fluid flow in clinically healthy gingiva. Quintessence Int 1990 Mar;21(3):191-5.
13. Muzzarelli R, et al. Reconstruction of parodontal tissue with chitosan. Biomaterials 1989 Nov;10(9):598-603.
14. Rubinoff AB, et al. Vitamin C and oral health. J Can Dent Assoc 1989 Sep;55(9):705-7.
15. Melnick SL, et al. A case-control study of plasma ascorbate and acute necrotizing ulcerative gingivitis. J Dent Res 1988 May;67(5):855-60.
16. Jacob RA, et al. Experimental vitamin C depletion and supplementation in young men. Nutrient interactions and dental health effects. Ann N Y Acad Sci 1987;498:333-46.
17. Leggott PJ, et al. The effect of controlled ascorbic acid depletion and supplementation on periodontal health. J Periodontol 1986 Aug;57(8):480-5.
18. Ellis CN, et al. Scurvy. A case caused by peculiar dietary habits. Arch Dermatol1984 Sep;120(9):1212-4.
19. Khan PK, et al. Vitamin C mediated amelioration of pesticide genotoxicity in murine spermatocytes. Cytobios 1994;80(323):199-204.
20.Sarma L, et al. Protective effects of vitamins C and E against gamma-ray-induced chromosomal damage in mouse. Int J Radiat Biol 1993 Jun;63(6):759-64.
21.Dreosti I, et al. Antioxidants and UV-induced genotoxicity. Res Commun Chem Pathol Pharmacol 1992 Feb;75(2):251-4.
22. Trizna Z, et al. Effects of N-acetyl-L-cysteine and ascorbic acid on mutagen-induced chromosomal sensitivity in patients with head and neck cancers. Am J Surg 1991 Oct;162(4):294-8.
23. Pohl H, et al. Vitamin C intake influences the bleomycin-induced chromosome damage assay: implications for detection of cancer susceptibility and chromosome breakage syndromes. Mutat Res 1989 Oct;224(2):247-52.
24. Pohl H, et al. Vitamin C intake influences the bleomycin-induced chromosome damage assay: implications for detection of cancer susceptibility and chromosome breakage syndromes. 1989 Mutat Res Oct;224(2):247-52.
25. Gebhart E, et al. The action of anticlastogens in human lymphocyte cultures and their modification by rat-liver S9 mix. II. Studies with vitamins C and E. Mutat Res 1985 Mar;149(1):83-94.
26. Antunes LM, et al. Effects of high doses of vitamins C and E against doxorubicin-induced chromosomal damage in Wistar rat bone marrow cells. Mutat Res 1998 Nov 9;419(1-3):137-43.
27. Tavares DC, et al. Protective effects of the amino acid glutamine and of ascorbic acid against chromosomal damage induced by doxorubicin in mammalian cells. Teratog Carcinog Mutagen 1998;18(4):153-61.
28. Cozzi R, et al. Ascorbic acid and beta-carotene as modulators of oxidative damage. Carcinogenesis 1997 Jan;18(1):223-8.
29. Makedonov GP, et al. [The anticlastogenic effect of ascorbic acid in relation to the damages inducedin human lymphocytes by the photomutagenic action of 8-methoxypsoralen and by ammonium molybdate]. Radiats Biol Radioecol 1995 Sep-Oct;35(5):726-9.
30. Makedonov GP, et al. [The anticlastogenic effect of ascorbic acid in relation to the damages induced in human lymphocytes by the photomutagenic action of 8-methoxypsoralen and by ammonium molybdate]. [Article in Russian] Radiats Biol Radioecol 1995 Sep-Oct;35(5):726-9.
31.Anderson D, et al. The effect of antioxidants on bleomycin treatment in in vitro and in vivo genotoxicity assays. Mutat Res 1995 Jun;329(1):37-47.
32. Piyathilake CJ, et al. Cigarette smoking, intracellular vitamin deficiency, and occurrence of micronuclei in epithelial cells of the buccal mucosa. Cancer Epidemiol Biomarkers Prev 1995 Oct-Nov;4(7):751-8.
33. Bilgrami KS, et al. Cumulative effect of T-2 toxin and vitamin C on chromosomal abnormalities in the bone marrow cells of mice (Mus musculus). Cytobios 1995;81(326):171-4.
34.Antunes LM, et al. Protection and induction of chromosomal damage by vitamin C in human lymphocyte cultures. Teratog Carcinog Mutagen 1999;19(1):53-9.
35. Konturek PC, et al. Helicobacter pylori associated gastric pathology. J Physiol Pharmacol 1999 Dec;50(5):695-710.
36. Bennedsen M, et al. Treatment of H. pylori infected mice with antioxidant astaxanthin reduces gastric inflammation, bacterial load and modulates cytokine release by splenocytes. Immunol Lett 1999 Dec 1;70(3):185-9.
37. Fraser AG, et al. Gastric juice ascorbic acid is related to Helicobacter pylori infection but not ethnicity.J Gastroenterol Hepatol 1999 Nov;14(11):1070-3.
38. Rokkas T, et al. Relationship of Helicobacter pylori CagA(+) status to gastric juice vitamin C levels. Eur J Clin Invest 1999 Jan;29(1):56-62.
39. Jarosz M, et al. Effects of high dose vitamin C treatment on Helicobacter pylori infection and total vitamin C concentration in gastric juice. Eur J Cancer Prev 1998 Dec;7(6):449-54.
40. Zhang ZW, et al. The relation between gastric vitamin C concentrations, mucosal histology, and CagA seropositivity in the human stomach. Gut 1998 Sep;43(3):322-6.
41. Drake IM, et al. Ascorbic acid may protect against human gastric cancer byscavenging mucosal oxygen radicals. Carcinogenesis 1996 Mar;17(3):559-62.
42. Retsky KL, et al. Vitamin C prevents metal ion-dependent initiation and propagation of lipid peroxidation in human low-density lipoprotein. Biochim Biophys Acta 1995 Aug 3;1257(3):279-87.
43. Scaccini C, et al. A critical assessment of the effects of aminoguanidine and ascorbate on the oxidative modification of LDL: evidence for interference with some assays of lipoprotein oxidation by aminoguanidine.J Lipid Res 1994 Jun;35(6):1085-92.
44. Scaccini C, et al. A critical assessment of the effects of aminoguanidine and ascorbate on the oxidative modification of LDL: evidence for interference with some assays of lipoprotein oxidation by aminoguanidine. J Lipid Res 1994 Jun;35(6):1085-92.
45. Azenabor AA, et al. Generation of reactive oxygen species and formation and membrane lipid peroxides in cells infected with Chlamydia trachomatis. Int J Infect Dis 2000;4(1):46-50.
46. Shilotri PG, et al. Effect of mega doses of vitamin C on bactericidal ativity of leukocytes. Am J Clin Nutr 1977 Jul;30(7):1077-81.
47. Anderson R. Effects of ascorbate on normal and abnormal leucocyte functions. Nutr Res Suppl 1982;23:23-34.
48. Corberand J, et al. Malignant external otitis and polymorphonuclear leukocyte migration impairment. Improvement with ascorbic acid. Arch Otolaryngol 1982 Feb;108(2):122-4.
49. Anderson R, et al . Effects of ascorbate on leucocytes: Part III. In vitro and in vivo stimulation of abnormal neutrophil motility by ascorbate. Arch Otolaryngol 1982 Feb;108(2):122-4S Afr Med J 1979 Sep 8;56(11):429-33.
50. Boura P, et al . Monocyte locomotion in anergic chronic brucellosis patients: the in vivo effect of ascorbic acid. Immunopharmacol Immunotoxicol 1989;11(1):119-29.
51. Foster CS, et al. Ascorbate therapy in impaired neutrophil and monocyte chemotaxis. With atopy, hyperimmunoglobulinemia E, and recurrent infection. Arch Ophthalmol 1978 Nov;96(11):2069-72.
52. Rebora A, et al. Repeated staphylococcal pyoderma in two siblings with defective neutrophil bacterial killing. Dermatologica 1980;160(2):106-12.
53. Patrone F, et al. Disorders of neutrophil function in children with recurrent pyogenic infections. Med Microbiol Immunol (Berl) 1982;171(2):113-22.
54. Patrone F, et al. Effects of ascorbic acid on neutrophil function. Studies on normal and chronic granulomatous disease neutrophils. Acta Vitaminol Enzymol 1982;4(1-2):163-8.
55. Rebora A, et al. Neutrophil dysfunction and repeated infections: influence of levamisole and ascorbic acid. Br J Dermatol 1980 Jan;102(1):49-56.
56. de la Fuente M, et al. Immune function in aged women is improved by ingestion of vitamins C and E. Can J Physiol Pharmacol 1998 Apr;76(4):373-80.
57. Levy R, et al. Successful treatment of a patient with recurrent furunculosis by vitamin C: improvement of clinical course and of impaired neutrophil functions. Int J Dermatol 1993 Nov;32(11):832-4.
58. Anderson R. Ascorbate-mediated stimulation of neutrophil motility and lymphocyte transformation by inhibition of the peroxidase/H2O2/halide system in vitro and in vivo. Am J Clin Nutr 1981 Sep;34(9):1906-11.
59. Ferrandez MD, et al. Effects in vitro of several antioxidants on the natural killer function of aging mice. Exp Gerontol 1999 Aug;34(5):675-85.
60. Heuser G, et al. Enhancement of natural killer cell activity and T and B cell function by buffered vitamin C in patients exposed to toxic chemicals: the role of protein kinase-C. Immunopharmacol Immunotoxicol 1997 Aug;19(3):291-312.
61. Hurlimann R, et al. [Scurvy--a mistakenly forgotten disease]. [Article in German] Schweiz Med Wochenschr 1994 Aug 9;124(31-32):1373-80.
62. Ghorbani AJ, et al. Scurvy. J Am Acad Dermatol 1994 May;30(5 Pt 2):881-3.
63. Valkonen MM, et al. Vitamin C prevents the acute atherogenic effects of passive smoking. Free Radic Biol Med 2000 Feb 1;28(3):428-36.
64. Galley HF, et al. Combination oral antioxidant supplementation reduces blood pressure. Clin Sci (Colch) 1997 Apr;92(4):361-5.
65. Gokce N, et al.Long-term ascorbic acid administration reverses endothelial vasomotor dysfunction in patients with coronary artery disease. Circulation 1999 Jun 29;99(25):3234-40.
66. Chambers JC, et al.Demonstration of rapid onset vascular endothelial dysfunction after hyperhomocysteinemia: an effect reversible with vitamin c therapy. Circulation 1999 Mar 9;99(9):1156-60.
67. Wilkinson IB, Megson IL, et al. Oral vitamin C reduces arterial stiffness and platelet aggregation in humans. J Cardiovasc Pharmacol 1999 Nov;34(5):690-3.
68. Jeserich M, et al. Vitamin C improves endothelial function of epicardial coronary arteries in patients with hypercholesterolaemia or essential hypertension--assessed by cold pressor testing. Eur Heart J 1999 Nov;20(22):1676-80.
69. Frei B . On the role of vitamin C and other antioxidants in atherogenesis and vascular dysfunction. Proc Soc Exp Biol Med 1999 Dec;222(3):196-204.
70. Fuller CJ, et al. Effect of ascorbate supplementation on low density lipoprotein oxidation in smokers. Atherosclerosis 1996 Jan 26;119(2):139-50.
71. Kuusi T . Vitamin C prevents the acute atherogenic effects of passive smoking.Valkonen MM, Free Radic Biol Med 2000 Feb 1;28(3):428-36.
72. Zhang J, et al. A single high dose of vitamin C counteracts the acute negative effect on microcirculation induced by smoking a cigarette. Microvasc Res 1999 Nov;58(3):305-11.
73. Purkayastha SS, et al. Effect of vitamin C and E in modulating peripheral vascular response to local cold stimulus in man at high altitude. Jpn J Physiol 1999 Apr;49(2):159-67.
74. Chamiec T, et al.Effects of antioxidant vitamins C and E on signal-averaged electrocardiogram in acute myocardial infarction. Am J Cardiol 1996 Feb 1; 77(4):237-41.
75. Gatto LM, et al. Ascorbic acid induces a favorable lipoprotein profile in women. J Am Coll Nutr 1996 Apr;15(2):154-8.
76. Singh RB, et al . Usefulness of antioxidant vitamins in suspected acute myocardial infarction (the Indian experiment of infarct survival-3). Am J Cardiol 1996 Feb 1;77(4):232-6.
77. Munoz JA, et al . Effect of VITAMIN C on lipoproteins in healthy adults. Ann Med Interne (Paris) 1994;145(1):13-9.
78. Tomoda H, et al. Possible prevention of postangioplasty restenosis by Ascorbic acid. Am J Cardiol 1996 Dec 1;78(11):1284-6.
79. Laskowski H, et al. Mortality and clinical course of patients with acute myocardial infarction treated with streptokinase and antioxidants: mannitol and Ascorbic acid. Int J Cardiol 1995 Mar 3;48(3):235-7.
80. Eriksson J, et al. Magnesium and Ascorbic acid supplementation in diabetes mellitus. Ann Nutr Metab 1995;39(4):217-23.
81. Cerna O,et al.Plasma lipids, lipoproteins and atherogenic index in men and women administered vitamin c. Cor Vasa 1992;34(3):246-54.
82. Barta E, et al.Protective effect of alpha-tocopherol and L-ascorbic acid against the ischemic-reperfusion injury in patients during open-heart surgery. Bratisl Lek Listy 1991 Mar-Apr;92(3-4):174-83.
83. Salonen JT,et al. Effects of antioxidant supplementation on platelet function: a randomized pair-matched, placebo-controlled, double-blind trial in men with low antioxidant status. Am J Clin Nutr 1991 May;53(5):1222-9.
84. Mayer-Davis EJ, et al. Vitamin c intake and cardiovascular disease risk factors in persons with non-insulin-dependent diabetes mellitus. From the Insulin Resistanc Atherosclerosis Study and the San Luis Valley Diabetes Study. rev Med 1997 May-Jun;26(3):277-83.
85. Bostom AG, et al.The effect of high-dose ascorbate supplementation on plasma lipoprotein(a) levels in patients with premature coronary heart disease. Pharmacotherapy 1995 Jul-Aug;15(4):458-64.
86. Westhuyzen J, et al.Effect of preoperative supplementation with alpha-tocopherol and ascorbic acid on myocardial injury in patients undergoing cardiac operations. J Thorac Cardiovasc Surg 1997 May;113(5):942-8.
87. Tanaka H, et al.Reduction of resuscitation fluid volumes in severely burned patients using ascorbic acid administration: a randomized, prospective study. Arch Surg 2000 Mar;135(3):326-31.
88. Kodama N, et al. Cisternal irrigation therapy with urokinase and ascorbic acid for prevention of vasospasm after aneurysmal subarachnoid hemorrhage. Outcome in 217 patients. Surg Neurol 2000 Feb;53(2):110-7; discussion 117-8.
89. Sinclair S, et al. Male infertility: nutritional and environmental considerations. Altern Med Rev 2000 Feb;5(1):28-38.
90. van Rooij J, et al. Oral vitamins C and E as additional treatment in patients with acute anterior uveitis: a randomised double masked study in 145 patients. Br J Ophthalmol 1999 Nov;83(11):1277-82.
91. Zollinger PE, et al. Effect of vitamin C on frequency of reflex sympathetic dystrophy in wrist fractures:a randomised trial. Lancet 1999 Dec 11;354 (9195):2025-8.
92. Gorton HC, et al. The effectiveness of vitamin C in preventing and relieving the symptoms of virus-induced respiratory infections. J Manipulative Physiol Ther 1999 Oct;22(8):530-3.
93. Vermeer IT, et al. Effect of ascorbic acid and green tea on endogenous formation of N-nitrosodimethylamine and N-nitrosopiperidine in humans. Mutat Res 1999 Jul 16;428(1-2):353-61.
94. Reinhold U, et al. Treatment of progressive pigmented purpura with oral bioflavonoids and ascorbic acid: an open pilot study in 3 patients. J Am Acad Dermatol 1999 Aug;41(2 Pt 1):207-8.
95. Hemila H. Vitamin C supplementation and common cold symptoms: factors affecting the magnitude of the benefit. Med Hypotheses 1999 Feb;52(2):171-8.
96. McAuliffe AV, et al. Administration of ascorbic acid and an aldose reductase inhibitor (tolrestat) in diabetes: effect on urinary albumin excretion. Nephron 1998 Nov;80(3):277-84.
97. de la Fuente M, et al. Immune function in aged women is improved by ingestion of vitamins C and E. Can J Physiol Pharmacol 1998 Apr;76(4):373-80.
98. Allard JP, et al. Effects of vitamin E and C supplementation on oxidative stress and viral load in HIV-infected subjects AIDS 1998 Sep 10;12(13):1653.
99. Eberlein-Konig B, et al. Phototoxic lysis of erythrocytes from humans is reduced after oral intake of Ascorbic acid and d-alpha-tocopherol. Photodermatol Photoimmunol Photomed 1997 Oct-Dec;13(5-6):173-7.
100. Alessio HM, et al.Exercise-induced oxidative stress before and after VITAMIN C supplementation. Int J Sport Nutr 1997 Mar;7(1):1-9.
101. Schwille PO, et al. Postprandial hyperinsulinaemia, insulin resistance and inappropriately high phosphaturia are features of younger males with idiopathic calcium urolithiasis: attenuation by Ascorbic acid supplementation of a test meal. Urol Res 1997;25(1):49-58.
102. Hemila H, et al. Vitamin C intake and susceptibility to the common cold. Br J Nutr 1997 Jan;77(1):59-72.
103. Gustafsson U, et al. The effect of VITAMIN C in high doses on plasma and biliary lipid composition in patients with cholesterol gallstones: prolongation of the nucleation time. Eur J Clin Invest 1997 May;27(5):387-91.
104. Jeng KC, et al.Supplementation with vitamins C and E enhances cytokine production by peripheral blood mononuclear cells in healthy adults. Am J Clin Nutr 1996 Dec;64(6):960-5.
105. McAlindon ME, et al. Effect of allopurinol, sulphasalazine, and VITAMIN C on aspirin induced gastroduodenal injury in human volunteers. Gut 1996 Apr;38(4):518-24.
106. Boffa MJ, et al. A double-blind, placebo-controlled, crossover trial of oral VITAMIN C in erythropoietic protoporphyria. Photodermatol Photoimmunol Photomed 1996 Feb;12(1):27-30.
107. Lonnrot K, et al. The effect of ascorbate and ubiquinone supplementation on plasma and CSF total antioxidant capacity. Free Radic Biol Med 1996;21(2):211-7.
108. Nadgrodkiewicz K , et al. [The effect of intravenous Ascorbic acid on urinary 17-hydroxysteroid excretion at an early stage of cerebral stroke]. Neurol Neurochir Pol 1996 Jan-Feb;30(1):49-56.
109. Wang H, et al. Experimental and clinical studies on the reduction of erythrocyte sorbitol-glucose ratios by Ascorbic acid in diabetes mellitus. Diabetes Res Clin Pract 1995 Apr;28(1):1-8.
110. Sharma DC, et al. .Correction of anemia and iron deficiency in vegetarians by administration of Ascorbic acid. Indian J Physiol Pharmacol 1995 Oct;39(4):403-6.
111. Paolisso G, et al. Metabolic benefits deriving from chronic VITAMIN C supplementation in aged non-insulin dependent diabetics. J Am Coll Nutr 1995 Aug;14(4):387-92.
112. Gastaldello K,et al.Resistance to erythropoietin in iron-overloaded haemodialysis patients can be overcome by Ascorbic acid administration. Nephrol Dial Transplant 1995;10 Suppl 6:44-7.
113. Skin wound healing process. A double-blind, prospective and randomized trial. Eur Surg Res 1995;27(3):158-66.
114. Wang H, Zhang ZB, et al. [Reduction of erythrocyte sorbitol by Ascorbic acid in patients with diabetes mellitus]. Chung Hua I Hsueh Tsa Chih 1994 Sep;74(9):548-51, 583.
115. Herbaczynska-Cedro K, et al. Inhibitory effect of vitamins C and E on the oxygen free radical production in human polymorphonuclear leucocytes. Eur J Clin Invest 1994 May;24(5):316-9.
116. Cunningham JJ, et al. VITAMIN C: an aldose reductase inhibitor that normalizes erythrocyte sorbitol in insulin-dependent diabetes mellitus. J Am Coll Nutr 1994 Aug;13(4):344-50.
117. Kataoka A, et al. [Intermittent high-dose VITAMIN C therapy in patients with HTLV-I-associated myelopathy]. Rinsho Shinkeigaku 1993 Mar;33(3):282-8.
118. Dumitrescu C, et al. Effect of VITAMIN C administration on the ratio between the pro- and antioxidative factors. Rom J Endocrinol 1993;31(1-2):81-4.
119. Karduss Urueta A, et al. [Results of the treatment of chronic idiopathic thrombocytopenic purpura with Ascorbic acid]. Gac Med Mex 1993 Jan-Feb;129(1):23-5.
120. Dawson EB, et al. Effect of Ascorbic acid supplementation on the sperm quality of smokers. Fertil Steril 1992 Nov;58(5):1034-9.
121. Triana Mantilla ME, et al. [The effect of VITAMIN C on the lipolytic activity in type-II diabetics with angiopathy]. [Article in Spanish] Angiologia 1991 Mar-Apr;43(2):77-81.
122. Reed PI, et al.Effect of Ascorbic acid on the intragastric environment in patients at increased risk of developing gastric cancer. IARC Sci Publ 1991;(105):139-42.
123. Beser E et al.The effects of short-term VITAMIN C on plasma bun, uric acid, cholesterol and triglyceride levels. Acta Med Hung 1991;48(1-2):73-8.
124. Bucca C, et al. Effect of VITAMIN C on histamine bronchial responsiveness of patients with allergic rhinitis. Ann Allergy 1990 Oct;65(4):311-4 Ann Allergy 1990 Oct;65(4):311-4.
125. Hunt JR, et al. Ascorbic acid: effect on ongoing iron absorption and status in iron-depleted young women. Am J Clin Nutr 1990 Apr;51(4):649-55.
126. Mai J, et al. High dose antioxidant supplementation to MS patients. Effects on glutathione peroxidase, clinical safety, and absorption of selenium. Biol Trace Elem Res 1990 Feb;24(2):109-17.
127. Mirvish SS, et al. Effect of ascorbic acid dose taken with a meal on nitrosoproline excretion in subjects ingesting nitrate and proline. Nutr Cancer 1998;31(2):106-10.
128. Seven A, et al. Biochemical evaluation of oxidative stress in propylthiouracil treated hyperthyroid patients. Effects of vitamin C supplementation. Clin Chem Lab Med 1998 Oct;36(10):767-70.
129.Heuser G, et al. Enhancement of natural killer cell activity and T and B cell function by buffered VITAMIN C in patients exposed to toxic chemicals: the role of protein kinase-C. Immunopharmacol Immunotoxicol 1997 Aug;19(3):291-312.
130. Liyanage C, et al. Iron absorption from a traditional Sri Lankan weaning food and the enhancing effect of Ascorbic acid in adult male volunteers. Ceylon Med J 1996 Dec;41(4):135-40.
131. Hunt C, et al. The clinical effects of VITAMIN Csupplementation in elderly hospitalised patients with acute respiratory infections. Int J Vitam Nutr Res 1994;64(3):212-9.
132. Johnston CS, et al. Megadose of VITAMIN C delays insulin response to a glucose challenge in normoglycemic adults. Am J Clin Nutr 1994 Nov;60(5):735-8.
133. Bednar C, et al. Nitrate and VITAMIN C from fruits and vegetables: impact of intake variations on nitrate and nitrite excretions of humans. Plant Foods Hum Nutr 1994 Jan;45(1):71-80.
134. Levin ED, et al. Clinical trials using Ascorbic acid aerosol to aid smoking cessation. Drug Alcohol Depend 1993 Oct;33(3):211-23.
135.Maxwell SR, et al. Changes in plasma antioxidant status during eccentric exercise and the effect of vitamin supplementation. Free Radic Res Commun 1993;19(3):191-202 .