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Life Extension Magazine





May 9, 2000

 

National Academy of Sciences References


 

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290. Berkson BM. A conservative triple antioxidant approach to the treatment of hepatitis C. Combination of alpha lipoic acid (thioctic acid), silymarin, and selenium: three case histories. Med Klin 1999 Oct 15;94 Suppl 3:84-9.

291. Look MP, et al. Interferon/antioxidant combination therapy for chronic hepatitis C--a controlled pilot trial. Antiviral Res 1999 Sep;43(2):113-22.

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295. Nenci GG, et al. [Diabetes, coagulation and vascular events]. Recenti Prog Med 2000 Feb;91(2):86-90.

296. Sharma A, et al. Evaluation of oxidative stress before and after control of glycemia and after vitamin E supplementation in diabetic patients. Metabolism 2000 Feb;49(2):160-2.

297. Ferber P, et al. High dose supplementation of RRR-alpha-tocopherol decreases cellular hemostasis but accelerates plasmatic coagulation in type 2 diabetes mellitus. Horm Metab Res 1999 Dec;31(12):665-71.

298. Paolisso G, et al. Chronic vitamin E administration improves brachial reactivity and increases intracellular magnesium concentration in type II diabetic patients.
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299. Kaneto H, et al. Beneficial effects of antioxidants in diabetes: possible protection of pancreatic beta-cells against glucose toxicity. Diabetes 1999 Dec;48(12):2398-406.

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301. Ferreira FM, et al. Decreased susceptibility to lipid peroxidation of Goto-Kakizaki rats: relationship to mitochondrial antioxidant capacity. Life Sci 1999;65(10):1013-25.

302. Skrha J, et al. Insulin action and fibrinolysis influenced by vitamin E in obese Type 2 diabetes mellitus. Diabetes Res Clin Pract 1999 Apr;44(1):27-33.

303. Gazis A, et al. Effect of oral vitamin E (alpha-tocopherol) supplementation on vascular endothelial function in Type 2 diabetes mellitus. Diabet Med 1999 Apr;16(4):304-11.

304. Davi G, et al. In vivo formation of 8-iso-prostaglandin f2alpha and platelet activation in diabetes mellitus: effects of improved metabolic control and vitamin E supplementation. Circulation 1999 Jan 19;99(2):224-9.

305. Tutuncu NB, et al. Reversal of defective nerve conduction with vitamin E supplementation in type 2 diabetes: a preliminary study. Diabetes Care 1998 Nov;21(11):1915-8.

306. Chung TW, et al. Reducing lipid peroxidation stress of erythrocyte membrane by alpha-tocopherol nicotinate plays an important role in improving blood rheological properties in type 2 diabetic patients with retinopathy. Diabet Med 1998 May;15(5):380-5

307. Yoshida H, et al. Vitamin E/lipid peroxide ratio and susceptibility of LDL to oxidative modification in non-insulin-dependent diabetes mellitus. Arterioscler Thromb Vasc Biol 1997 Jul;17(7):1438-46.

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309. Salonen JT, et al. Increased risk of non-insulin dependent diabetes mellitus at low plasma vitamin E concentrations: a four year follow up study in men. BMJ 1995 Oct 28;311(7013):1124-7.

310. Caballero B. Vitamin E improves the action of insulin. Nutr Rev 1993 Nov;51(11):339-40.

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315. Sokoloski JA, et al. Induction of the differentiation of HL-60 promyelocytic leukemia cells by vitamin E and other antioxidants in combination with low levels of vitamin D3: possible relationship to NF-kappaB. Leukemia 1997 Sep;11(9):1546-53

316. Swain RA, et al. Therapeutic uses of vitamin E in prevention of atherosclerosis. Altern Med Rev 1999 Dec;4(6):414-23.

317. Wu D, et al. Effect of vitamin E on human aortic endothelial cell production of chemokines and adhesion to monocytes. Atherosclerosis 1999 Dec;147(2):297-307.

318. Davey PJ, et al. Cost-effectiveness of vitamin E therapy in the treatment of patients with angiographically proven coronary narrowing (CHAOS trial). Cambridge Heart Antioxidant Study. Am J Cardiol 1998 Aug 15;82(4):414-7.

319. Polasek J. Acetylsalicylic acid and vitamin E in prevention of arterial thrombosis. Can J Cardiol 1997 May;13(5):533-5.

320. Hoogwerf BJ, et al. The HOPE study. Ramipril lowered cardiovascular risk, but vitamin E did not. Cleve Clin J Med 2000 Apr;67(4):287-93.

321. Matthai J. Vitamin E updated. Indian J Pediatr 1996 Mar-Apr;63(2):242-53.

322. Floreani A, et al. Plasma antioxidant levels in chronic cholestatic liver diseases. Aliment Pharmacol Ther 2000 Mar;14(3):353-8.

323. Watson JP, et al. Case report: oral antioxidant therapy for the treatment of primary biliary cirrhosis: a pilot study. J Gastroenterol Hepatol 1999 Oct;14(10):1034-40.

324. Copp RP, et al. Localization of alpha-tocopherol transfer protein in the brains of patients with ataxia with vitamin E deficiency and other oxidative stress related neurodegenerative disorders. Brain Res 1999 Mar 20;822(1-2):80-7.

325. Tanyel MC, et al. Neurologic findings in vitamin E deficiency. Am Fam Physician 1997 Jan;55(1):197-201.

326.Arria AM, et al. Vitamin E deficiency and psychomotor dysfunction in adults with primary biliary cirrhosis. Am J Clin Nutr 1990 Aug;52(2):383-90.

327.Winklhofer-Roob BM, et al. Short-term changes in erythrocyte alpha-tocopherol content of vitamin E-deficient patients with cystic fibrosis. Am J Clin Nutr 1992 Jan;55(1):100-3.

328. Margolis S, et al. Nutritional management of plasma lipid disorders. J Am Coll Nutr 1989;8 Suppl:33S-45S.

329. Jeffrey GP, et al. Vitamin E deficiency and its clinical significance in adults with primary biliary cirrhosis and other forms of chronic liver disease. J Hepatol 1987 Jun;4(3):307-17.

330. Perlmutter DH, et al. Intramuscular vitamin E repletion in children with chronic cholestasis. Am J Dis Child 1987 Feb;141(2):170-4.

331. Knight RE, et al. Neurologic syndrome associated with low levels of vitamin E in primary biliary cirrhosis. Gastroenterology 1986 Jul;91(1):209-11.

332. Larsen PD, et al. Vitamin E deficiency associated with vision loss and bulbar weakness. Ann Neurol 1985 Dec;18(6):725-7.

333. Machlin LJ.Clinical uses of vitamin E. Acta Vitaminol Enzymol 1985;7 Suppl:33-43.

334. Morrow MJ Neurologic complications of vitamin E deficiency: case report and review of the literature. Bull Clin Neurosci 1985;50:53-60.

335. Saito K, et al. Pathology of chronic vitamin E deficiency in fatal familial intrahepatic cholestasis (Byler disease). Virchows Arch A Pathol Anat Histol 1982 Aug;396(3):319-30.

336. Rosenblum JL, et al. A progressive neurologic syndrome in children with chronic liver disease. N Engl J Med 1981 Feb 26;304(9):503-8.

337. Franceschi S Nutrients and food groups and large bowel cancer in Europe. Eur J Cancer Prev 1999 Dec;9 Suppl 1:S49-52.

338. Woodson K, et al. Serum alpha-tocopherol and subsequent risk of lung cancer among male smokers. J Natl Cancer Inst 1999 Oct 20;91(20):1738-43.

339. Lopez-Carrillo L, et al. Nutrient intake and gastric cancer in Mexico. Int J Cancer 1999 Nov 26;83(5):601-5.

340. Ronco A, et al. Dietary antioxidants and lung cancer risk: a case-control study in Uruguay. Nutr Cancer 1999;34(1):100-10.

341. Yang CS Vitamin nutrition and gastroesophageal cancer. J Nutr 2000 Feb;130(2S Suppl):338S-339S.

342. Ahmed MI, et al. Lipid peroxidation and antioxidant status in human cervical carcinoma. Dis Markers 1999 Dec;15(4):283-91.

343. Elattar TM, et al. Biphasic action of vitamin E on the growth of human oral squamous carcinoma cells. Anticancer Res 1999 Jan-Feb;19(1A):365-8.

344. Launoy G, et al. Diet and squamous-cell cancer of the oesophagus: a French multicentre case-control study. Int J Cancer 1998 Mar 30;76(1):7-12.

345. Bairati I, et al. [Prevention of second primary cancer with vitamin supplementation in patients treated for head and neck cancers]. Bull Cancer Radiother 1996;83(1):12-6.

346. El Attar TM, et al. Vitamin E succinate potentiates the inhibitory effect of prostaglandins on oral squamous carcinoma cell proliferation. Prostaglandins Leukot Essent Fatty Acids 1995 Jan;52(1):69-73.

347. Gottlober P, et al. [The treatment of cutaneous radiation-induced fibrosis with pentoxifylline and vitamin E. An empirical report]. Strahlenther Onkol 1996 Jan;172(1):34-8.

348.Schwartz JL, et al. Altered cytokeratin expression in carcinogenesis inhibition by antioxidant nutrients. Nutr Cancer 1995;24(1):47-56.

349. ElAttar TM, et al. Inhibition of human oral squamous carcinoma cell (SCC-25) proliferation by prostaglandin E2 and vitamin E succinate. J Oral Pathol Med 1993 Oct;22(9):425-7.

350. Schwartz JL, et al. Molecular and biochemical reprogramming of oncogenesis through the activity of prooxidants and antioxidants. Ann N Y Acad Sci 1993 May 28;686:262-78; discussion 278-9.

351. Schwartz J, et al. The selective cytotoxic effect of carotenoids and alpha-tocopherol on human cancer cell lines in vitro. J Oral Maxillofac Surg 1992 Apr;50(4):367-73; discussion 373-4.

352. ElAttar TM, et al. Inhibition of growth in oral squamous carcinoma cells by cyclopentenone prostaglandins: comparison with chemotherapeutic agents. Prostaglandins Leukot Essent Fatty Acids 1997 Jun;56(6):461-5.

353. Klipstein-Grobusch K, et al. Dietary antioxidants and risk of myocardial infarction in the elderly: the Rotterdam Study. Am J Clin Nutr 1999 Feb;69(2):261-6.

354. Gey KF Vitamins E plus C and interacting conutrients required for optimal health. A critical and constructive review of epidemiology and supplementation data regarding cardiovascular disease and cancer. Biofactors 1998;7(1-2):113-74.

355. Schroder H, et al. Nutrition antioxidant status and oxidative stress in professional basketball players: effects of a three compound antioxidative supplement. Int J Sports Med 2000 Feb;21(2):146-50.

356. Welch RW, et al. Dietary antioxidant supplementation and DNA damage in smokers and nonsmokers. Nutr Cancer 1999;34(2):167-72 .

357. Chen D, et al. [The inhibitory effects of antioxidant vitamins on serum oxLDL and experimental atherosclerosis of rabbits]. Chung Kuo I Hsueh Ko Hsueh Yuan Hsueh Pao 1997 Dec;19(6):451-5.

358. Fillion L, et al. Beta-carotene enhances the recovery of lymphocytes from oxidative DNA damage. Acta Biochim Pol 1998;45(1):183-90 .

359. Linselsen J., et al. Effect of a single oral dose of antioxidant mixture (vitamin E, carotenoids) on the formation of cholesterol oxidation products after ex vivo LDL oxidation in humans. Eur J Med Res 1998 Feb 21;3(1-2):5-12.

360. Dixon ZR, et al. The effect of a low carotenoid diet on malondialdehyde-thiobarbituric acid (MDA-TBA) concentrations in women: a placebo-controlled double-blind study. Eur J Med Res 1998 Feb 21;3(1-2):5-12.

361. Sumida S, et al. Effect of a single bout of exercise and beta-carotene supplementation on the urinary excretion of 8-hydroxy-deoxyguanosine in humans. Free Radic Res 1997 Dec;27(6):607-18.

362. Meraji S, et al. Enhanced plasma level of lipid peroxidation in Iranians could be improved by antioxidants supplementation. Eur J Clin Nutr 1997 May;51(5):318-25.

363. Omaye ST, et al. Blood antioxidants changes in young women following beta-carotene depletion and repletion. J Am Coll Nutr 1996 Oct;15(5):469-74.

364. Kanter MM, et al. Effects of an antioxidant vitamin mixture on lipid peroxidation at rest and postexercise. J Appl Physiol 1993 Feb;74(2):965-9.

365. Chao WH, et al. Oxidative stress in humans during work at moderate altitude. J Nutr 1999 Nov;129(11):2009-12.

366. Bunout D, et al. Effects of supplementation with folic acid and antioxidant vitamins on homocysteine levels and LDL oxidation in coronary patients. Nutrition 2000 Feb;16(2):107-10.

367. Lee BM, et al. Inhibition of oxidative DNA damage, 8-OHdG, and carbonyl contents in smokers treated with antioxidants (vitamin E, vitamin C, beta-carotene and red ginseng). Cancer Lett 1998 Oct 23;132(1-2):219-27.

368. Howard DJ, et al. Oxidative stress induced by environmental tobacco smoke in the workplace is mitigated by antioxidant supplementation. Cancer Epidemiol Biomarkers Prev 1998 Nov;7(11):981-8.

369. Porrini M, et al. Lymphocyte lycopene concentration and DNA protection from oxidative damage is increased in women after a short period of tomato consumption. J Nutr 2000 Feb;130(2):189-92.

370. Steinberg FM, et al. Antioxidant vitamin supplementation and lipid peroxidation in smokers. Am J Clin Nutr 1998 Aug;68(2):319-27 Published erratum appears in Am J Clin Nutr 1999 Jun;69(6):1293.

371. Stahl W, et al. Carotenoid mixtures protect multilamellar liposomes against oxidative damage: synergistic effects of lycopene and lutein. FEBS Lett 1998 May 8;427(2):305-8.

372. Fleshner NE, et al. Diet, androgens, oxidative stress and prostate cancer susceptibility. Cancer Metastasis Rev 1998-99;17(4):325-30.

373. Rao AV, et al. Serum and tissue lycopene and biomarkers of oxidation in prostate cancer patients: a case-control study. Nutr Cancer 1999;33(2):159-64.

374. Riso P, et al.Does tomato consumption effectively increase the resistance of lymphocyte DNA to oxidative damage? Am J Clin Nutr 1999 Apr;69(4):712-8.

375. Lowe GM, et al. Lycopene and beta-carotene protect against oxidative damage in HT29 cells at low concentrations but rapidly lose this capacity at higher doses. Free Radic Res 1999 Feb;30(2):141-51.

376. Stahl W, et al. Carotenoids and carotenoids plus vitamin E protect against ultraviolet light-induced erythema in humans. Am J Clin Nutr 2000 Mar;71(3):795-8.

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379. Anderson JW, et al. Antioxidant supplementation effects on low-density lipoprotein oxidation for individuals with type 2 diabetes mellitus. Am Coll Nutr 1999 Oct;18(5):451-61.

380. Gann PH, et al. Lower prostate cancer risk in men with elevated plasma lycopene levels: results of a prospective analysis. Cancer Res 1999 Mar 15;59(6):1225-30.

381. Murata M, et al. Oxidative DNA damage by vitamin A and its derivative via superoxide generation. J Biol Chem 2000 Jan 21;275(3):2003-8.

382. Knekt P, et al. Serum antioxidant vitamins and risk of cataract. BMJ 1992 Dec 5;305(6866):1392-4.

383. Riedl J, et al. Some dietary fibers reduce the absorption of carotenoids in women. J Nutr 1999 Dec;129(12):2170-6.

384. Castenmiller JJ, et al. beta-carotene does not change markers of enzymatic and nonenzymatic antioxidant activity in human blood. J Nutr 1999 Dec;129(12):2162-9.

385. Speizer FE, et al. Prospective study of smoking, antioxidant intake, and lung cancer in middle-aged women (USA). Cancer Causes Control 1999 Oct;10(5):475-82.

386. Ascherio A, et al. Relation of consumption of vitamin E, vitamin C, and carotenoids to risk for stroke among men in the United States. Ann Intern Med 1999 Jun 15;130(12):963-70.

387. Shaish A, et al. Dietary beta-carotene and alpha-tocopherol combination does not inhibit atherogenesis in an ApoE-deficient mouse model. Arterioscler Thromb Vasc Biol 1999 Jun;19(6):1470-5.

388. Lugli SM, et al. Stimulation of cell division in the rat by NaCl, KCl, MgCl2, and CaCl2, and inhibition of the sodium chloride effect on the glandular stomach by ascorbic acid and beta-carotene. J Cancer Res Clin Oncol 1999;125(3-4):209-13.

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390. West KP Jr, et al. Double blind, cluster randomised trial of low dose supplementation with vitamin A or beta-carotene on mortality related to pregnancy in Nepal. The NNIPS-2 Study Group. BMJ 1999 Feb 27;318(7183):570-5.

391. Faulks RM, et al. Changes in plasma carotenoid and vitamin E profile during supplementation with oil palm fruit carotenoids. J Lab Clin Med 1998 Dec;132(6):507-11.

392. Romieu I, et al. Antioxidant supplementation and respiratory functions among workers exposed to high levels of ozone. Am J Respir Crit Care Med 1998 Jul;158(1):226-32.

393. Mark SD, et al. Do nutritional supplements lower the risk of stroke or hypertension? Epidemiology 1998 Jan;9(1):9-15.

394. Johnson MA, et al. Micronutrient supplementation and infection in institutionalized elders. Nutr Rev 1997 Nov;55(11 Pt 1):400-4.

395. Longnecker MP, et al. Intake of carrots, spinach, and supplements containing vitamin A in relation to risk of breast cancer. Cancer Epidemiol Biomarkers Prev 1997 Nov;6(11):887-92.

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399. Zondervan KT, et al. Do dietary and supplementary intakes of antioxidants differ with smoking status? Int J Epidemiol 1996 Feb;25(1):70-9.

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404. Buring JE, et al. beta-carotene and cancer chemoprevention. J Cell Biochem Suppl 1995;22:226-30.

405. Taylor PR, et al. Prevention of esophageal cancer: the nutrition intervention trials in Linxian, China. Linxian Nutrition Intervention Trials Study Group. Cancer Res 1994 Apr 1;54(7 Suppl):2029s -2031s.

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407. Park E, et al. Effects of multivitamin/mineral supplementation, at nutritional doses, on plasma antioxidant status and DNA damage estimated by sister chromatid exchanges in lymphocytes in pregnant women. Int J Vitam Nutr Res 1999 Nov;69(6):396-402.

408. Wang XD, et al. Procarcinogenic and anticarcinogenic effects of beta-carotene. Nutr Rev 1999 Sep;57(9 Pt 1):263-72.

409. Hughes DA Effects of carotenoids on human immune function. Proc Nutr Soc 1999 Aug;58(3):713-8.

410. Stefani ED, et al. Dietary antioxidants and lung cancer risk: a case-control study in Uruguay. Nutr Cancer 1999;34(1):100-10.