Life Extension Magazine

Life Extension Magazine June 2004

Are You Afraid of Terrorists?

By William Faloon

LE Magazine June 2004

Are You Afraid of Terrorists?

Preventing Cancer with Anti-Aging Therapies
The best experimental model to prevent the onset of cancer and other age-related diseases is caloric restriction. In every study to date in which caloric restriction extended mammal life span, it also showed dramatic anticancer effects.48-55 In its search for anti-aging therapies, BioMarker has found changes in gene expression in calorie-restricted mice that suggest several anticancer mechanisms induced by caloric restriction. One such mechanism involves “chaperone” genes, which regulate the synthesis, maturation, processing, transport, repair, and degradation of proteins. With advancing age, damaged proteins play a major role in the deterioration of the body’s critical systems.

Gene expression is the first step in determining the activity and decline of the body’s systems. The next step is the actions that genes have on proteins and other substances in the body. BioMarker is planning to conduct proteomic studies with specimens of tissue it preserved when conducting its previous gene chip experiments. Proteomic research will enable BioMarker scientists to trace the effects of changes in gene expression on physiologic changes in aging tissues, which will in turn allow the company to find out more about anti-aging and anti-disease mechanisms.

BioMarker is collaborating with scientists at the National Cancer Institute in the design of studies that will attempt to elucidate mechanisms that could lead to the development of new anti-aging and anticancer therapies.

A New Product to Make You Look Better Today
In this month’s issue, we introduce a MicroDermAbrasion product that makes people look younger by exfoliating dead and damaged cells from the skin’s surface. This exfoliate was invented by a dermatologist who tested it on hundreds of patients in order to develop the optimal particle size needed to safely expose healthier-appearing skin cells.

While MicroDermAbrasion is primitive technology compared to our genomic research, proceeds from the sale of this appearance-enhancing product help us meet the enormous costs of conducting gene expression chip studies on compounds that may enable us to slow and even reverse the aging process.

Today, almost 6,500 Americans will silently perish from cancer, heart attack, or one of the many other diseases of aging. You will not hear about this on the evening news. Instead, the media will cover stories relating to terrorism threats or isolated violent acts. Life Extension cannot do much about these problems, but we are dedicated to protecting the lives of Americans who die needlessly because of governmental ineptitude and neglect.

Every time you purchase a Life Extension product that provides you with immediate benefits, you also help fund lifesaving scientific research.

For longer life,
image

William Faloon.

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