Life Extension Magazine

Life Extension Magazine July 2008

Report

Life Extension Clinical Research

By Steven P. Hirsh, RPH, DPM, MHSA

By Steven P. Hirsh, RPH, DPM, MHSA

Why You Should Consider Participating

Life Extension is the world leader in identifying natural approaches to prevent disease and slow aging.

Unlike commercial companies, Life Extension conducts research on human study subjects to validate published scientific findings and to establish optimal dose ranges.

In this article, we outline new clinical studies for which we are enrolling study subjects. Members are encouraged to review these research projects to see if they may personally benefit by participating in one of these clinical studies.

In exchange for participating, you are given free blood tests, nutritional supplements, and personalized consultations that can be worth thousands of dollars.

As a member of the Life Extension Foundation, you seek the latest technological advances to protect against age-related degeneration. As a participant in a clinical study, you gain access to novel nutritional approaches that may significantly improve your health and longevity.

Scientific Research

Before Life Extension brings a product to its members, each component of that product undergoes extensive scrutiny, including evaluation of any available published clinical research studies. In addition, the evaluation process often continues by means of clinical trials conducted in the facilities of Life Extension® Clinical Research, Inc. (LECR), in Fort Lauderdale, Florida, as well as outside Life Extension.

Life Extension Clinical Research comprises physicians, scientists, pharmacists, statisticians, data managers, project managers, and clinical research coordinators. We have consistently and extensively substantiated our products’ potential benefits. These efforts have assisted our organization in creating better ways for our members to maintain and improve their health.

The product development team at Life Extension continually reviews the scientific literature for natural agents that have shown promise in combatting age-related disorders. Life Extension’s clinical studies are designed, managed, and conducted to discover new benefits to Life Extension’s members by providing the highest-quality products and ensuring the safety of our clinical study subjects.

Recently Conducted Studies

Recent clinical studies at Life Extension have been conducted in the following areas:

  • Cardiovascular endothelial function

  • Healthy cholesterol levels

  • Body weight

  • Sleep/mood/appetite levels

  • Male sexual health

  • Hair-growth inhibition

  • Coenzyme Q10 bioavailability

  • Blood sugar

  • Male hormone levels.

One of the most essential aspects in conducting a clinical study is having the necessary number of volunteers participate. By taking part in a clinical trial at Life Extension Clinical Research, you will have the opportunity to take a nutritional supplement and contribute to a potential health breakthrough.

What You Need to Know: Life Extension’s Clinical Research Program
  • Life Extension was founded more than 25 years ago with the goal of researching therapies to extend the healthy human life span and bringing these remedies to the public.

  • Life Extension Clinical Research conducts clinical trials to document the efficacy of a variety of products in human subjects.

  • To date, Life Extension has conducted clinical trials on products designed for diverse health concerns, including supporting healthy endothelial function, male sexual health, and healthy cholesterol levels.

  • Currently, Life Extension Clinical Research is recruiting subjects for clinical trials related to supporting healthy HDL cholesterol levels, male hormone levels, female urinary tract health, inflammation, healthy mood and sleep, and promoting healthy blood sugar levels.

  • You may register as a volunteer in any of the trials at Life Extension Clinical Research by calling (866) 517-4536 or (954) 202-7678, or by visiting the Life Extension Clinical Research section.

Currently Recruiting for Clinical Trials

At the present time, we are recruiting healthy volunteers for clinical trials that apply to a wide range of potential health benefits. Please see the table below for ongoing trials.

How Do I Register as a Volunteer?

There are two ways to register for one of our exciting clinical studies. You may register by:

1. Calling the main telephone number for Life Extension Clinical Research at 866-517-4536 or locally in the South Florida area at 954-202-7678.

OR

2. Logging on to the website and following these steps:

  • a. Go to http://www.lifeextension.com.

  • b. Scroll to the bottom left corner of the page and click on “Life Extension Clinical Research.”

  • c. Click on “Register for open studies” on the right side.

  • d. Click on the study that is most appealing to you, such as: “Improving HDL Cholesterol Levels” or “Improving Male Hormone Levels.”

  • e. Read a brief description of the study.

  • f. If interested, click on “Register.”

  • g. Complete the registration form.

  • h. Click on “Register Now” and you will automatically be registered. When the study is ready to commence, or if it has already commenced, you will be contacted by the study coordinator.

By participating as a volunteer in the clinical trials at Life Extension Clinical Research, you not only benefit yourself but also the whole Life Extension family.

How to Participate

Clinical Research, Clinical Trials, Clinical Studies

Life Extension Clinical Research, Inc. is a clinical research organization engaged in the investigation of natural nutritional supplements that enhance and support optimal health. Your participation in these studies entitles you to FREE blood tests, nutritional supplements, and consultations worth thousands of dollars.

In addition to furthering medical science, you will gain access to state-of-the-art nutritional approaches for chronic discomforts that could literally turn your life around for the better.

If you are interested in participating in any of these studies, there are two easy ways to do so:

1. Call the main telephone number for Life Extension Clinical Research at: (866) 517-4536 or (954) 202-7678.

2. Log directly into the Life Extension website by using the following steps:

a. Go to http://www.lifeextension.com

b. Scroll to Life Extension Clinical Research on the bottom left corner of the page, click, and follow the directions

Dr. Steven Hirsh is Director of Clinical Research at Life Extension Clinical Research, Inc.

If you have any questions on the scientific content of this article, please call a Life Extension Health Advisor at 1-800-226-2370.

Ongoing Trial

Geographic Area

Evaluation

Trial Requirements

1.Supporting healthy high-density lipoprotein (HDL) levels

Nationwide

Effectiveness of a natural nutritional
formula designed to safely support optimal blood HDL levels

Healthy male and female volunteers
21-70 years old
Low blood values of beneficial HDL
Access to a LabCorp blood-lab
facility

2.Optimizing male hormone levels

Nationwide

Effectiveness of a natural nutritional
supplement designed to safely support
optimal hormone levels

Healthy male volunteers
50-70 years old
Low testosterone and high estradiol levels
Access to a LabCorp blood-lab facility

3.Female urinary tract health

Tri-county area of South Florida (Dade, Broward, and Palm Beach counties)

Effectiveness of a natural cranberry-based formula designed to promote urinary tract health

• Healthy female volunteers
• 21-45 years old
• Two or more urinary tract infections (UTI) within the past six months

4.Inflammation

Tri-county area of South Florida (Dade, Broward, and Palm Beach counties)

Effectiveness of a natural nutritional formula designed to target specific prostaglandin pathways in the body

• Healthy male and female volunteers
• 21-65 years old
• Signs of excess inflammation in
the body (e.g. an elevated blood C-reactive protein level)

5.Supporting sleep and maintaining a healthy mood

Nationwide

Effectiveness of a natural nutritional
formula designed to support sleep and
maintain healthy mood/energy levels

• Healthy male and female volunteers
• 21-70 years old
• Looking to improve sleep, mood,
and energy and lessen fatigue

6.Supporting healthy blood sugar levels

Tri-county area of South Florida (Dade, Broward, and Palm Beach counties)

Effectiveness of a nutritional supplement designed to support optimal blood sugar
levels

• Healthy male and female volunteers
• 21-70 years old
• Looking to achieve healthy blood
sugar levels