Life Extension Magazine November 2010
Halt Age-Related Muscle Loss
By Robert Haas, MS
Agave Inulin and FOS: A Powerful Prebiotic Blend
Prebiotics feed beneficial intestinal bacterial flora. The natural prebiotics inulin and fructooligosaccharides (FOS) occur in more than 36,000 species of the world’s flora.47 Thus, it is almost certain that the diets of our prehistoric forebears consisted of foods rich in prebiotics.48 Presumably, the human digestive tract evolved to depend on the health-supporting properties of prebiotics.
Current studies reveal that long-chain prebiotics like inulin extracted from the fiber of the agave plant, unlike many other short-chain prebiotics, arrive at the colon intact and remain longer, allowing them to effectively support the growth of the beneficial digestive tract bacteria, Lactobacilli and Bifidobacteria.49
Food scientists have devised a strategy of using agave-derived inulin and FOS in protein supplements and functional foods to promote the growth of indigenous Bifidobacteria in the gut.50 These prebiotics interact in a selective way with our intestinal ecosystem and can favorably transform its composition, providing tremendous potential for gut health, chemoprevention, and immunity.51,52
An emerging body of research suggests that consuming inulin-based prebiotics directly diminishes the risk of chronic diseases by:
Data from human studies suggests that fermentation of prebiotic carbohydrates stimulates colonic motility and promotes proliferation of Bifidobacteria, both of which have been shown to relieve constipation.70,71 In one study, fecal weight increased in response to supplementation with either FOS or inulin.72
Oat Beta-glucans For Glycemic and Cholesterol Control
Numerous animal and human studies have established oat beta-glucans as an important dietary aid in the treatment of diabetes and cardiovascular disorders. Oat bran in particular is good source of the heart-healthy soluble fiber beta-glucan.73
Oat beta-glucans have been shown to promote a healthy postprandial glycemic response.74-78 In addition, oat beta-glucans can lower cholesterol levels in adults with elevated lipid levels. One clinical study examined the effects of feeding oat bran beta-glucans to men and women with high cholesterol. Participants were able to achieve significant reductions in plasma cholesterol levels by the study’s end.79
Aging adults often require more protein than younger adults—a fact established by clinical studies, yet ignored by our leading health organizations.
Nearly 50% of all adults run the risk of developing sarcopenia, a serious age-related loss of muscle mass. Age-related muscle loss is a leading cause of preventable disability and loss of functional capacity in older adults.
Adults, vegetarians, and all active people can benefit from a new proprietary protein supplement product enriched with pea and other plant proteins, branch chained amino acids, prebiotics, and cholesterol-lowering oat beta-glucans. These components work in concert to maximize protein utilization, while controlling the postprandial glycemic response that inflicts so much damage to cells after every high-calorie meal we eat.
If you have any questions on the scientific content of this article, please call a Life Extension® Health Advisor at
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