1. Liu J, et al. Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding aceyl-l-carnitine and/or R-alpha- lipoic acid. Proc Natl Acad Sci USA 2002 Feb 19;99(4):2356-61.
2. Hagen TM, et al. Feeding acetyl-l-carntine and lipoic acid to old rats significantly improves the metabolic function while decreasing oxidative stress. Proc Natl Acad Sci USA 2002 Feb 19;99(4):1870-5.
3. Giancaterini A, et al. Acetyl-L-carnitine infusion increases glucose disposal in type 2 diabetic patients. Metabolism 2000 Jun;49(6):704-8.
4. Yamano T,et al. Effect of L-carnosine on the hyperglycemia caused by intracranial injection of 2-deoxy-D-glucose in rats. Neurosci Lett 2001 Nov 2;313(1-2):78-82.
5. Packer L, et al. Molecular aspects of lipoic acid in the prevention of diabetes complications. Nutrition 2001 Oct;17(10):888-95.
6. Ford I, et al. The effects of treatment with alpha-lipoic acid or evening primrose oil on vascular hemostatic and lipid risk factors, blood flow, and peripheral nerve conduction in the streptozotocin-diabetic rat. Metabolism 2001 Aug;50(8):868-75.
7. Coppey LJ, et al. Effect of antioxidant treatment of streptozotocin-induced diabetic rats on endoneurial blood flow, motor nerve conduction velocity and vascular reactivity of epineurial arterioles of the sciatic nerve. Diabetes 2001 Aug;50(8):1927-37.
8. Cameron NE, et al. Effect of alpha-lipoic acid on vascular responses and nociception in diabetic rats. Free Radic Biol Med 2001 Jul 1;31(1):125-35.
9. Heitzer T, et al. Beneficial effects of alpha-lipoic acid and ascorbic acid on endothelium-dependent, nitric oxide-mediated vasodilation in diabetic patients: relation to parameters of oxidative stress. Free Radic Biol Med 2001 Jul 1;31(1):53-61.
10. Ukeda H, et al. Effect of carnosine and related compounds on the inactivation of human Cu,Zn-superoxide dismutase by modification of fructose and glycolaldehyde. Biosci Biotechnol Biochem 2002 Jan;66(1):36-43.
11. Hipkiss AR. On the “struggle between chemistry and biology during aging”--implications for DNA repair, apoptosis and proteolysis, and a novel route of intervention. Biogerontology 2001;2(3):173-8.
12. Packer Let al. Molecular aspects of lipoic acid in the prevention of diabetes complications. Nutrition 2001 Oct;17(10):888-95.
13. Melhem MF, et al. Alpha-lipoic acid attenuates hyperglycemia and prevents glomerular mesangial matrix expansion in diabetes. J Am Soc Nephrol 2002 Jan;13(1):108-16.
14. Virmani MA, et al. The action of acetyl-L-carnitine on the neurotoxicity evoked by amyloid fragments and peroxide on primary rat cortical neurones. Ann N Y Acad Sci 2001 Jun;939:162-78.
15. Zhang L, et al. Alpha-lipoic acid protects rat cortical neurons against cell death induced by amyloid and hydrogen peroxide through the Akt signalling pathway. Neurosci Lett 2001 Oct 26;312(3):125-8.
16. Dukic-Stefanovic S, et al. AGES in brain ageing: AGE-inhibitors as neuroprotective and anti-dementia drugs? Biogerontology 2001;2(1):19-34.
17. Price DL, et al. Chelating activity of advanced glycation end-product inhibitors. J Biol Chem 2001 Dec 28;276(52):48967-72.
18. Ando S, et al. Enhancement of learning capacity and cholinergic synaptic function by carnitine in aging rats. J Neurosci Res 2001 Oct 15;66(2):266-71.
19. Pettegrew JW, et al. Acetyl-L-carnitine physical-chemical, metabolic, and therapeutic properties: relevance for its mode of action in Alzheimer’s disease and geriatric depression. Mol Psychiatry 2000 Nov;5(6):616-32.
20. Sorbi S, et al. Double-blind, crossover, placebo-controlled clinical trial with L-acetylcarnitine in patients with degenerative cerebellar ataxia. Clin Neuropharmacol 2000 Mar-Apr;23(2):114-8.
21. Andreassen OA, et al. Lipoic acid improves survival in transgenic mouse models of Huntington’s disease. Neuroreport 2001 Oct 29;12(15):3371-3.
22. Hager K, et al. Alpha-lipoic acid as a new treatment option for Azheimer type dementia. Arch Gerontol Geriatr 2001 Jun;32(3):275-282.
23. Gonzalez-Perez O, et al. Beneficial effects of alpha-lipoic acid plus vitamin E on neurological deficit, reactive gliosis and neuronal remodeling in the penumbra of the ischemic rat brain. Neurosci Lett 2002 Mar 15;321(1-2):100-4.
24. Piotrowski P, et al. Neuronal death in the rat hippocampus in experimental diabetes and cerebral ischaemia treated with antioxidants. Folia Neuropathol 2001;39(3):147-54.
25. Liu J, et al. Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid. Proc Natl Acad Sci U S A 2002 Feb 19;99(4):2356-61.
26. Hagen TM, et al. Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress. Proc Natl Acad Sci U S A 2002 Feb 19;99(4):1870-5.
27. Zhang WJ, Frei B. Alpha-lipoic acid inhibits TNF-alpha-induced NF-kappaB activation and adhesion molecule expression in human aortic endothelial cells. FASEB J 2001 Nov;15(13):2423-32.
28. Decker EA, et al. Inhibition of low-density lipoprotein oxidation by carnosine histidine. J Agric Food Chem 2001 Jan;49(1):511-6.
29. El Midaoui A, de Champlain J. Prevention of hypertension, insulin resistance, and oxidative stress by alpha-lipoic acid. Hypertension 2002 Feb;39(2):303-7.
30. Takaoka M, et al. Effects of alpha-lipoic acid on deoxycorticosterone acetate-salt-induced hypertension in rats. Eur J Pharmacol 2001 Jul 20;424(2):121-9.
31. Hipkiss AR, et al. Carnosine, the anti-aging, anti-oxidant dipeptide, may react with protein carbonyl groups. Mech Ageing Dev 2001 Sep 15;122(13):1431-45.
32. Roberts PR, Zaloga GP. Cardiovascular effects of carnosine. Biochemistry (Mosc) 2000 Jul;65(7):856-61.
33. Arivazhagan P, et al. Effect of DL-alpha-lipoic acid on glutathione metabolic enzymes in aged rats. Exp Gerontol 2001 Dec;37(1):81-7.
34. Koufaki M, et al. Novel potent inhibitors of lipid peroxidation with protective effects against reperfusion arrhythmias. J Med Chem 2001 Nov 22;44(24):4300-3.
35. Pack RA, et al. Differential effects of the antioxidant alpha-lipoic acid on the proliferation of mitogen-stimulated peripheral blood lymphocytes and leukaemic T cells. Mol Immunol 2002 Feb;38(10):733-45.
36. Casciari JJ, et al.. Cytotoxicity of ascorbate, lipoic acid, and other antioxidants in hollow fibre in vitro tumours. Br J Cancer 2001 Jun 1;84(11):1544-50.
37. Mollica MP, et al. Acetyl-L-carnitine treatment stimulates oxygen consumption and biosynthetic function in perfused liver of young and old rats. Cell Mol Life Sci 2001 Mar;58(3):477-84.
38. Niang M, Melka M. Effect of acetyl-L-carnitine on leukemia L1210 resistant to mitoxantrone. Acta Medica (Hradec Kralove) 2000;43(4):125-8.
39. Patrick L. Nutrients and HIV: part three - N-acetylcysteine, alpha-lipoic acid, L-glutamine, and L-carnitine. : Altern Med Rev 2000 Aug;5(4):290-305.
40. Mangano NG, et al. Effect of acetyl-L-carnitine on ethanol consumption and alcohol abstinence syndrome in rats. Drugs Exp Clin Res 2000;26(1):7-12.
41. Persson HL, et al. Alpha-lipoic acid and alpha-lipoamide prevent oxidant-induced lysosomal rupture and apoptosis. Redox Rep 2001;6(5):327-34.
42. Dietrich M, et al. Antioxidant supplementation decreases lipid peroxidation biomarker F(2)-isoprostanes in plasma of smokers. Cancer Epidemiol Biomarkers Prev 2002 Jan;11(1):7-13.
43. Akhalaia MIa, et al. Effect of natural radioprotector carnosine on histamine-diamine oxidase system of rat’s myocardium after action of various extreme factors. Radiats Biol Radioecol 2001 Jan-Feb;41(1):56-8.
44. Nagasawa T, et al. In vitro and in vivo inhibition of muscle lipid and protein oxidation by carnosine. Mol Cell Biochem 2001 Sep;225(1-):29-34.
45. Arivazhagan P, et al. Effect of DL-alpha-lipoic acid on mitochondrial enzymes in aged rats. Chem Biol Interact 2001 Nov 28;138(2):189-98.
46. Logan AC, Wong C. Chronic fatigue syndrome: oxidative stress and dietary modifications. Altern Med Rev 2001 Oct;6(5):450-9.
47. Saengsirisuwan V, et al. Interactions of exercise training and lipoic acid on skeletal muscle glucose transport in obese Zucker rats. J Appl Physiol 2001 Jul;91(1):145-53.