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Life Extension Magazine

Top Ten Recommendations

1: Life Extension Mix

2: Life Extension Super Booster

3: Coenzyme Q10

4: Mitochondrial Energy Optimizer

5: Cognitex

6: Super EPA/DHA with Sesame Lignans

7: Enhanced Natural Prostate with Cernitin (Men)

7: Bone Restore (Women)

8: Restoring Youthful Hormone Balance

9: S-adenosyl-methionine (SAMe)

10: Aspirin

Life Extension Mix
Multivitamin-Mineral-Herbal-Amino Acid Formula

DOSAGE: 3 tablets with breakfast; 3 tablets with lunch; 3 tablets with dinner. (Also available in capsule and powder form.)

Public service campaigns are encouraging people to eat more fruits and vegetables to protect against degenerative disease. Despite years of media publicity, an AC Nielsen poll released August 24, 2004 reported that 85% of Americans are not even eating the minimum recommendation of five servings of fruits and vegetables per day. Those who do report eating some produce often fail to consume the yellow and purple colored plants that are such critical components of a disease prevention program.

Life Extension Mix™ contains 92 unique vegetable, fruit, and herbal extracts along with high quantities of amino acids, vitamins, minerals, and special antioxidants. The Life Extension Mix™ formula is fortified with botanical extracts that help to maintain healthy cells via physiological processes separate from traditional antioxidants. Consumption of these types of plants is being recommended based on research emanating from the most prestigious medical centers in the world.

Standardized Green Tea Extract
The Life Extension Foundation introduced green tea extract as a supplement in 1993 based on epidemiological studies showing that those who consumed green tea had much lower incidences of common degenerative disorders. Over the past 11 years, there have been more positive studies about the health benefits of green tea than any other nutrient.

Scientists have looked at the active “polyphenol” constituents of green tea and have found that they possess remarkable biological activity at the cellular level. Scientists have also identified multiple mechanisms by which green tea extract protects against undesirable cell propagation, LDL oxidation, neuronal peroxidation, and a host of other adverse structural and functional age-related changes.1-7

The new Life Extension Mix™ provides 325 mg of a decaffeinated green tea extract that is standardized to contain 302 mg of the polyphenols that is attributed to green tea’s health benefits.

Members who have been supplementing with one Super Green Tea Extract capsule a day can now eliminate that supplement. The amount of polyphenols (including EGCG) in the new Life Extension Mix™ is equivalent to drinking about 3-6 cups of green tea per day.8

More Vegetable Extracts
Luteolin is a flavonoid found in parsley, artichoke, basil, celery, and other foods. When measured against 27 other flavonoids, luteolin had the second most anti-proliferative activity against undesirable cell colonies.9

One favorable mechanism of luteolin is its ability to inhibit oxidative damage to cellular DNA. Another unique benefit is luteolin’s ability to suppress excess levels of dangerous inflammatory inducers such as interleukin-6, tumor necrosis factor-alpha, and nuclear factor-kappa beta.10-12

The previous version of Life Extension Mix™ provided between 1.5-4 mg of luteolin per daily dose. The new Life Extension Mix™ contains a standardized dose of 8 mg of luteolin, which is two-to-five times more than what members where obtaining before.

Broccoli is touted as one of the most important vegetables to protect against the formation of undesirable cell colonies. Broccoli contains several active constituents, with sulphoraphane being the most significant because of its unique detoxification and DNA protecting effects. The new Life Extension Mix™ provides a concentrated broccoli mixture that provides standardized extracts of sulphoraphane and glucosinolates, two compounds attributed to broccoli’s multiple protective benefits. Broccoli is also a natural source of gene protecting chlorophyll.13-21

D-glucarate is a botanical extract found in grapefruit, apples, oranges, broccoli, and brussels sprouts.

D-glucarate effectively supports a detoxification process that helps to remove DNA toxins from the body22-24 The daily dose of Life Extension Mix™ provides 200 mg of D-glucarate.

Lutein, an extract found in spinach and collard greens, has been shown to help maintain critical pigments in the eye macula, while the carotenoid alpha carotene has demonstrated antioxidant activity far greater than beta-carotene. Lycopene from tomatoes has shown potent effects in reducing LDL oxidation inhibiting undesirable prostate cell propagation.25-29 Life Extension Mix™ contains 60 times more lutein and 10 times more lycopene compared to Centrum®. Most multivitamin supplements provide no vegetable extracts whatsoever.

More Fruit Extracts
Life Extension Mix™ is also fortified with fruit extracts such as bilberry, grape seed, grape skin, and citrus bioflavonoids to provide healthy circulation throughout the body and protect against DNA alterations.

Ellagic acid is a detoxifying agent found in raspberries, strawberries, and other fruit. Ellagic acid has demonstrated DNA-protecting properties, including the ability to bind to toxins and neutralize them. Studies have also shown that ellagic acid may protect against chromosome damage and reduce the effects of chemically induced hepatic structural degeneration. Studies show that people who consume diets high in fruits that contain ellagic acid have lower rates of undesirable cell colony formation.30-32 Life Extension Mix™ contains a raspberry and pomegranate fruit extract to deliver 50 mg of ellagic acid in each daily dose.

The media has publicized the multiple benefits of fruits such as blueberry, blackberry, cranberry, plums, strawberry, and watermelon. The new Life Extension Mix™ has a customized blend of these and other fruits that studies indicate provide multiple favorable effects in the body.

Olive oil consumption is one of the important factors behind the health benefits of the “Mediterranean Diet.”33-34 Researchers have recently discovered that there are up to 300 times more polyphenol compounds in olive water compared to olive oil.35-36 Olive polyphenols have been the subject of numerous in vitro, in vivo, and human studies pointing toward their benefits in many different areas, including protecting against LDL oxidation, suppressing free radicals, and stabilizing cell membranes.37-39 The new Life Extension Mix™ contains a high concentration of olive juice extract standardized to contain 8% of the best-documented polyphenol called hydroxytyrosol.33 The amount of hydroxytyrosol in the daily dose of Life Extension Mix™ is equivalent to drinking over 6 ounces of olive oil a day.40-41

Sesame Lignans Enhance the Effects of Vitamin E
Sesame and its lignans have a broad range of applications in human health. This includes increasing human tissue levels of vitamin E by facilitating carrier proteins in the liver to deliver nutrients to cells throughout the body.42,43 Sesame lignans increase the benefits of fish oils, decrease LDL oxidation, inhibit lipid peroxidation, maintain healthy cholesterol/LDL levels in humans, and provide many other benefits.44-47

The new Life Extension Mix™ provides 10 mg of a sesame lignan extract to not only provide the direct benefits of the lignans, as well as augment the effects of vitamin E and other nutrients in the body such as gamma tocopherol and gamma linolenic acid (GLA). The remarkable findings about sesame lignans are explained throughout this special issue of Life Extension magazine.

Maintaining Healthy Blood Glucose Levels
Chromium, along with magnesium and biotin, are nutrients required to maintain optimal blood sugar levels. The new Life Extension Mix™ provides 500 mcg of chromium (compared to 200 mcg in the previous version), a better absorbable form of magnesium, and the same high potency of biotin. A review of studies showing benefits to chromium supplementation reveals that doses exceeding 200 mcg a day is required for optimal effects.48-53

More Vitamin D3
Doctors used to be concerned that too much vitamin D could be toxic. Over the past few years, however, an increasing body of evidence indicates that it takes much higher doses of vitamin D (perhaps over 10,000 IU/day) to create toxicity in a healthy person. The concern expressed by researchers today is that fear of vitamin D toxicity is keeping many people from supplementing with enough vitamin D, which is critical for maintaining bone density and protecting against the formation of undesirable cell colonies.54-59 In response to studies showing that even those who take standard vitamin D supplements are not obtaining adequate amounts, the new Life Extension Mix™ provides 800 IU of vitamin D3 per daily dose (compared to 400 IU in the previous version).

The Most Complete Multi-Nutrient Formula
Life Extension Mix™ saves time and money by combining the most popular nutrient supplements into one product, eliminating the need to take separate bottles of B-complex, vitamins C and E, mineral supplements, and much more that would be required to achieve the same effects.

Life Extension Mix™ supplies the most powerful antioxidants, including water and fat soluble vitamin C, the ideal form of alpha vitamin E, along with plant extracts that enhance beneficial DNA methylation patterns, help support cellular DNA, and help prevent the oxidation of LDL that contributes to the buildup of deposits in the endothelial lining.

Life Extension Mix™ is the cornerstone of a comprehensive supplement program because it provides so many well-studied nutrients. If you are on a budget, the Life Extension Mix™ provides the best “cost-per-milligram” value.

Turn to the next page for a complete description of the new Life Extension Mix™ formula.

More Info on Life Extension Mix

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