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Life Extension Magazine

Top Ten Recommendations

1: Life Extension Mix

2: Life Extension Super Booster

3: Coenzyme Q10

4: Mitochondrial Energy Optimizer

5: Cognitex

6: Super EPA/DHA with Sesame Lignans

7: Enhanced Natural Prostate with Cernitin (Men)

7: Bone Restore (Women)

8: Restoring Youthful Hormone Balance

9: S-adenosyl-methionine (SAMe)

10: Aspirin

Recommendation: 3
Coenzyme Q10

DOSAGE: 30 to 200 mg per day.

Coenzyme Q10 (CoQ10) is incorporated into cells’ mitochondria throughout the body where it facilitates and regulates the oxidation of fats and sugars into energy. Aging humans have been found to have 57% less CoQ10 on average compared to that of young adults.1-3 This finding makes CoQ10 one of the most important nutrients for people over 30 to supplement with.

About 95% of cellular energy is produced in the mitochondria. The mitochondria are the cells “energy powerhouses” and many maladies have been referred to as “mitochondrial disorders.”4-7 A growing body of scientific research links a deficiency of CoQ10 to age-related mitochondrial disorders.

The Life Extension Foundation was the first organization (in 1983) to introduce CoQ10 to the American public. Since that time, many new scientific studies on CoQ10 document the multiple health benefits of this versatile nutrient.

The heart is often adversely affected by a CoQ10 deficiency,8-11 but increasing evidence indicates that the brain is the organ most likely to suffer from an inadequate supply of CoQ10.12,13 Since cells need CoQ10 for energy production, the result of a CoQ10 deficiency can be seen in a greater incidence of age-associated disorders.

Cost of Taking Coenzyme Q10 Reduced
Life Extension’s new Super Absorbable CoQ10 is emulsified in a brand new delivery system that significantly increases its assimilation into the bloodstream. Because CoQ10 is a relatively expensive supplement, it is important to absorb as many ingested milligrams of this critical nutrient as possible.

The coenzyme Q10 used in this new super absorbable emulsion system comes from the finest Japanese pharmaceutical-grade supplier and is available in 30 mg, 100 mg, and 200 mg strength emulsified softgel caps. Despite the patent-pending technology that has gone into developing this super-delivery system, the price to Life Extension members remains the same.

Three potencies of the new Super-Absorbable CoQ10 are now available at low Super Sale prices.

To order the new Super Absorbable CoQ10 softgels at the lowest “cost per absorbable milligram” in the world, call 1-800-544-4440.

Note: While CoQ10 has antioxidant properties, its effects on boosting mitochondrial energy levels can result in the generation of additional free radicals. That is why it is important to take CoQ10 with other potent antioxidants, like Life Extension Mix and/or Life Extension Booster (or the new Gamma E Tocopherol with Sesame Lignans formula).

More Info on Coenzyme Q10

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1. Rosenfeldt FL, Pepe S, Ou R, et al. Coenzyme Q10 improves the tolerance of the senescent myocardium to aerobic and ischemic stress: studies in rats and in human atrial tissue. Biofactors. 1999;9(2-4):291-9.

2. Kalen A, Appelkvist EL, Dallner G. Age-related changes in the lipid compositions of rat and human tissues. Lipids. 1989 Jul;24(7):579-84.

3. Hoppe U, Bergemann J, Diembeck W, et al. Coenzyme Q10, a cutaneous antioxidant and energizer. Biofactors. 1999;9(2-4):371-8. Review.

4. Artuch R, Colome C, Vilaseca MA, et al. Ubiquinone: metabolism and functions. Ubiquinone deficiency and its implication in mitochondrial encephalopathies. Treatment with ubiquinone. Rev Neurol. 1999 Jul 1-15;29(1):59-63 (in Spanish).

5. Geromel V, Darin N, Chretien D, et al. Coenzyme Q(10) and idebenone in the therapy of respiratory chain diseases: rationale and comparative benefits. Mol Genet Metab. 2002 Sep-Oct;77(1-2):21-30.

6. Vedanarayanan VV. Mitochondrial disorders and ataxia. Semin Pediatr Neurol. 2003 Sep;10(3):200-9.

7. Cooper JM, Schapira AH. Friedreich’s Ataxia: disease mechanisms, antioxidant and Coenzyme Q10 therapy. Biofactors. 2003;18(1-4):163-71.

8. Hofman-Bang C, Rehnqvist N, Swedberg K, et al. Coenzyme Q10 as an adjunctive in the treatment of chronic congestive heart failure. The Q10 Study Group. J Card Fail. 1995 Mar;1(2):101-7.

9. Morisco C, Trimarco B, Condorelli M. Effect of coenzyme Q10 therapy in patients with congestive heart failure: a long-term multicenter randomized study. Clin Investig. 1993;71(8 Suppl):S134-6.

10. Langsjoen H, Langsjoen P, Willis R, et al. Usefulness of coenzyme Q10 in clinical cardiology: a long-term study. Mol Aspects Med. 1994;15 Suppl:s165-75.

11. Davini A, Cellerini F, Topi PL. Coenzyme Q10: contractile dysfunction of the myocardial cell and metabolic therapy. Minerva Cardioangiol. 1992 Nov;40(11):449-53 (in Italian).

12. Naini A, Lewis VJ, Hirano M, et al. Primary coenzyme Q10 deficiency and the brain. Biofactors. 2003;18(1-4):145-52.

13. Matthews RT, Yang L, Browne S, et al. Coenzyme Q10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects. Proc Natl Acad Sci U S A. 1998 Jul 21;95(15):8892-7.