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Top Ten Recommendations

1: Life Extension Mix

2: Life Extension Super Booster

3: Coenzyme Q10

4: Mitochondrial Energy Optimizer

5: Cognitex

6: Super EPA/DHA with Sesame Lignans

7: Enhanced Natural Prostate with Cernitin (Men)

7: Bone Restore (Women)

8: Restoring Youthful Hormone Balance

9: S-adenosyl-methionine (SAMe)

10: Aspirin

Recommendation: 7 (Men)
Enhanced Natural Prostate with Cernitin

DOSAGE: One capsule with breakfast and one capsule at bedtime.


Back in the 1980s, the most frequent complaint Life Extension used to hear were aging men lamenting about their enlarged prostate glands. We helped many members by identifying a product used in Europe called Permixon® that provided urinary relief to those with prostate problems. Foundation members who ordered Permixon® from Europe reported noticeable improvements in prostate health.

Dietary supplement companies soon realized that Permixon® was actually saw palmetto extract, which meant it could be manufactured and sold in the United States. Saw palmetto extract became an instant success and hundreds of supplement companies now offer it.
If Life Extension could accept mediocrity, saw palmetto would still be the solution for aging members seeking prostate support.

Instead, Life Extension scanned the world’s literature and discovered that combinations of saw palmetto with pygeum or nettle root extracts provided greater overall benefits. Life Extension developed the first prostate formula to contain the identical concentrations of saw palmetto, nettle root, and pygeum extracts used in European studies on men to protect the prostate and help maintain its healthy function.

The name of this saw palmetto-pygeum-nettle root extract was Natural Prostate Formula. Since its introduction in the 1990s, it has been upgraded with added lycopene and boron. These two nutrients were included in the Natural Prostate formula because they may be used to maintain healthy cell colonies.1-7

Since its inception, Natural Prostate has been an enormous success. It is one of the most re-ordered products Life Extension offers. There was one additional ingredient, however, that was showing increasing evidence of benefit. The latest new ingredient added to the Natural Prostate formula is a bee pollen extract called Cernitin. Some studies indicate that Cernitin works as well or better than saw palmetto extract, and may work by different mechanisms than saw palmetto.8-13

The daily dose of two capsules of Enhanced Natural Prostate with Cernitin provides:

Saw palmetto (super critical extract)

320 mg

Pygeum extract (13% pygeum sterols)

100 mg

Urtica dioca (nettle root) extract

240 mg

Lycopene extract

10 mg

Boron (amino acid chelate)

3 mg

Cernitin

252 mg

Although Cernitin is an expensive ingredient, it has been added to the Enhanced Natural Prostate Formula at no additional charge. Read more about the benefits of Cernitin in maintaining healthy prostate function in the December 2004 issue of Life Extension magazine.

For optimal savings, most members order a one-year supply of this advanced prostate support formula during the annual Super Sale.

More Info on Enhanced Natural Prostate with Cernitin

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References

1. Ansari MS, Gupta NP. A comparison of lycopene and orchidectomy vs orchidectomy alone in the management of advanced prostate cancer. BJU Int. 2003 Sep;92(4):375-8.

2. Kim L, Rao AV, Rao LG. et al. Effect of lycopene on prostate LNCaP cancer cells in culture. J Med Food. 2002 Winter;5(4):181-7.

3. Kucuk O, Sarkar FH, Djuric Z, et al. Effects of lycopene supplementation in patients with localized prostate cancer. Exp Biol Med (Maywood). 2002 Nov;227(10):881-5.

4. Vogt TM, Mayne ST, Graubard BI, et al. Serum lycopene, other serum carotenoids, and risk of prostate cancer in US Blacks and Whites. Am J Epidemiol. 2002 Jun 1;155(11):1023-32.

5. Giovannucci E, Rimm EB, Liu Y, et al. A prospective study of tomato products, lycopene, and prostate cancer risk. J Natl Cancer Inst. 2002 Mar 6;94(5):391-8.

6. Cui Y, Winton MI, Zhang ZF, et al. Dietary boron intake and prostate cancer risk. Oncol Rep. 2004 Apr;11(4):887-92.

7. Gallardo-Williams MT, Chapin RE, King PE, et al. Boron supplementation inhibits the growth and local expression of IGF-1 in human prostate adenocarcinoma (LNCaP) tumors in nude mice. Toxicol Pathol. 2004 Jan-Feb;32(1):73-8.

8. Loschen G, Ebeling L. Inhibition of arachidonic acid cascade by extract of rye pollen. Arzneimittelforschung. 1991 Feb;41(2):162-7 (in German).

9. Habib FK, Ross M, Buck AC, et al. In vitro evaluation of the pollen extract, cernitin T-60, in the regulation of prostate cell growth. Br J Urol. 1990 Oct;66(4):393-7.

10. Buck AC, Cox R, Rees RW, et al. Treatment of outflow tract obstruction due to benign prostatic hyperplasia with the pollen extract, cernilton. A double-blind, placebo-controlled study. Br J Urol. 1990 Oct;66(4):398-404.

11. Talpur N, Echard B, Bagchi D, et al. Comparison of Saw Palmetto (extract and whole berry) and Cernitin on prostate growth in rats. Mol Cell Biochem. 2003 Aug;250(1-2):21-6.

12. Maekawa M, Kishimoto T, Yasumoto R, et al. Clinical evaluation of Cernilton on benign prostatic hypertrophy—a multiple center double-blind study with Paraprost. Hinyokika Kiyo. 1990 Apr;36(4):495-516 (in Japanese).

13. Preuss HG, Marcusen C, Regan J, et al. Randomized trial of a combination of natural products (cernitin, saw palmetto, B-sitosterol, vitamin E) on symptoms of benign prostatic hyperplasia (BPH). Int Urol Nephrol. 2001;33(2):217-25.