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Life Extension Magazine

LE Magazine October 2004

My Interview with Suzanne Somers

How Life Extension Membership Can Save Your Life
In this issue of Life Extension, we present novel approaches that aging women should consider when it comes to safe hormone restoration. We also talk a lot about Suzanne Somers and her book, which is now in the hands of so many women. Suzanne was able to treat her cancer with a drug that is not approved by the FDA. While the efficacy of this particular drug remains questionable, Suzanne presents a compelling story to justify her right to access any drug that she believes would increase her chances of staying alive.

We do not agree with everything in Suzanne’s book, but if it takes a celebrity to get the message across about the necessity of maintaining youthful hormone balance—while personally defying FDA dictates—we welcome the support. Our long-standing position is that the FDA is the roadblock that separates Americans from breakthrough medical discoveries.

As a member of the Life Extension Foundation, you gain access to in-depth analyses of complex medical issues that are comprehensible to the lay reader. We recommend Suzanne Somers’ new book because it so well describes the critical need for hormone restoration. If you had to rely on Suzanne’s book alone, however, you would only get part of the story. Life Extension members gain access to the collective experiences of physicians and scientists who have used safe and natural approaches to hormone replacement for decades, despite FDA persecution.

The Life Extension Foundation has long exposed misleading government propaganda about the failed war against cancer. While survival rates have improved for some cancers over the past 30 years, the government ignores the harsh reality that many of the allegedly “cured” cancer victims suffer horribly from their treatments. The Life Extension Foundation continues to be the voice that challenges the overwhelming power of the cancer establishment, and informs our members about realities the federal government would prefer to hide from the public.

If you are not yet a Life Extension member, I invite you to peruse this month’s issue and ask yourself how valuable the information you read really is. On one side is the cancer establishment, supported financially, legally, and politically by the federal government. The objective of the cancer establishment is to pretend that significant progress is being made, though much of this so-called “success” is a result of earlier diagnosis and not better treatments. Life Extension, on the other hand, has consistently exposed the egregious misrepresentations made to the American public by the cancer establishment. Life Extension represents the consumer against an entrenched establishment that seeks to maintain its economic stranglehold on cancer research and treatment dollars.

As a member of our 24-year-old Foundation, you gain access to the latest medical breakthroughs, along with personalized access to Life Extension staff doctors by telephone. The free telephone contact alone could be worth hundreds of dollars, but membership in the Life Extension Foundation costs only $75 a year. Life Extension endeavors to take care of its members’ health concerns by incorporating the latest scientific findings in practical disease prevention and treatment protocols.

I hope the articles in this month’s issue are impressive enough to convince you that Life Extension membership is the best investment you could ever make in yourself.

For longer life,

William Faloon


As you can see from the following list, estrogen and progesterone drugs come in a wide range of choices.
Here we list the most commonly prescribed estrogen-progestin drugs and the type of estrogen, along with
the dosage units.

Brand Name

Type of Estrogen and Dosage Units

Oral Estradiol Drugs


Estradiol 0.5 mg, 1 mg, 2 mg
Estradiol 0.02 mg, 0.05 mg, 1 mg

Estinyl® comes in a lower-dose strength because it has a much longer-acting effect in the body.

Transdermal Estradiol Drugs

Alora®, Climara®, Esclim™, Vivelle®

Estradiol matrix patch
Estradiol matrix patch
Estradiol reservoir patch
Estradiol topical emulsion 1.7 g twice daily

Estradiol patches have variable rates of estradiol release over 24 hours and are changed once or twice weekly depending on the patch used.

Vaginal Cream, Gel, Ring, or Tablet Estradiol Drugs (for vaginal symptoms only)

Estrace® Vaginal (cream)
Estring® (ring)
Vagifem® (tablet)

Estradiol (0.01%) = 0.1 mg/dose
Estradiol 2 mg (7 ug over 24 hrs)
Estradiol 25 ug per tablet

Conjugated Estrogen Drugs

Premarin® Vaginal (cream)
Premarin® (oral)

Conjugated estrogens 0.625 mg/g
*Conjugated estrogens 0.3 mg, 0.45 mg, 0.625 mg, 0.9 mg, 1.25 mg, 2.5 mg.
*0.3 mg, 0.45 mg, 0.625 mg, 0.9 mg
0.3 mg, 0.625 mg, 1.25 mg, 2.5 mg

These drugs consist of 75-85% sodium estrone sulfate and 6-15% sodium equilin sulfate in such proportion that combined these total not less than 90% of the total esterified estrogens content. (Source: Facts and Comparisons, 2004 ed.)

* The manufacturers of Cenestin® (Barr Labs) and Premarin® (Wyeth) would not confirm the percentages of any of the estrogen components in their formulas, stating that this is “proprietary information.” Note that Premarin® is a natural, animal-based product derived from pregnant mare’s urine, unlike other commonly prescribed products such as Estrace® (soy based) and Cenestin® (yam based)

Oral Estrone Drugs



Estrone 0.75 mg and 1.5 mg
Estrone 0.625 mg, 1.25 mg, 2.5 mg

Oral Estriol Drugs

Estriol (generic only)

Estriol 4 mg, 8 mg

Commonly Prescribed Estrogen-Progestogen (Progestin) Drugs


Activella™, FemHrt® 1/5, Prefest®, Premphase®, Prempro™
Climara Pro™ and Combipatch®

Note: Progestogens and progestins are progesterone-like substances but are not structurally or biologically identical to progesterone. These include medroxyprogesterone acetate, norethindrone acetate, and levonorgestrel.

Progesterone-Only Medications Non-bioidentical to humans

Avgestin®, Aygestin®

Medroxyprogesterone acetate 2.5 mg, 5 mg
Norethindrone acetate 5 mg

Bioidentical Progesterone

Prometrium® (micronized progesterone)

100 mg, 200 mg capsules

(Note: Natural progesterone capsules are not recommended because the liver first metabolizes them before they enter the bloodstream. Natural progesterone creams are a better choice.)

Common Bioidentical Hormone Formulations


A combination of human bioidentical estradiol and estriol compounded by a pharmacist. It may come in varying per- centages of each hormone and the total milligram dose may differ depending on what the doctor orders. A common start- ing dose is 80% estriol and 20% estradiol, with a total dosage of 1.25 mg providing 0.25 mg of estradiol and 1 mg of estriol. The dose can be titrated upward. It comes in oral, top- ical cream, gel, or a lozenger (troche). Most think of an 80:20 ratio when they think of BiEst®. Because the medication is compounded to order, the physician can order whatever he or she believes will work best for each patient.


A combination of estradiol, estriol, and estrone. It may also come in varying percentages and the total dose may differ depending on what the doctor orders. A common starting dose is 80% estriol, 10% estradiol, and 10% estrone, with a total dosage of 1.25-2.5 mg. The dose can be titrated upward. Comes in the same options as BiEst® (oral, topical, or lozenger). Most think of the 80:10:10 ratio when they think of TriEst®, but the physician can order whatever ratio he or she believes will work best for the patient.


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