An analysis published online in the journal Pharmacological Research reviews the role of antioxidants in the treatment of infertility issues in men and women and concludes that the compounds show significant promise via their effects on vascular function.*
“While the direct effects of antioxidant treatment on the quality of semen and oocytes are still under investigation, a significant body of evidence points to loss of vascular tone as a root-cause of erectile dysfunction and, possibly, alterations to female reproduction,” write authors Francesco Visioli and Tory M. Hagen.
The authors remark that nitric oxide synthesis and bioavailability, which play a major role in vascular function, are impaired by compounds known as free radicals. These damaging molecules can be controlled, in part, by increasing the availability of antioxidants. While commonly supplemented antioxidants, including vitamins C and E, may be helpful, other antioxidants, such as lipoic acid, may have a more profound benefit.
Editor’s Note: Dr. Hagen added that treatment with antioxidants, “Might help prevent other critical health problems as well, at an early stage when nutritional therapies often work best.”