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Life Extension Magazine

Life Extension Magazine May 2014
As We See It  

CDC Says: 200,000 Americans Die Needlessly Every Year

By William Faloon

Low Testosterone Associated With Higher Vascular Risk

Low Testosterone Associated With Higher Vascular Risk  

Testosterone levels are high in young men, but plummet during aging.

Low testosterone in men is associated with excess abdominal fat,93,94 loss of insulin sensitivity,95,96 atherosclerosis,97,98 and increased incidence of cardiovascular disease.99

A review of data gathered between 1970 and 2013 provided further evidence that low testosterone in men may be linked to a higher risk of developing or dying from cardiovascular disease.100

Another 2013 study confirmed the increase of metabolic syndrome in men that are testosterone deficient.101 Metabolic syndrome is a cluster of cardiovascular risk factors that include insulin resistance, hypertension, elevated triglycerides/LDL and low HDL.102 This study found that men treated with testosterone showed across the board improvements as indicated by:101

Low Testosterone Associated With Higher Vascular Risk  
  • Reduced LDL.
  • Reduced triglycerides.
  • Reduced glucose.
  • Reduced C-reactive protein.
  • Reduced measures of liver damage.
  • Reduced blood pressure.
  • Reduced hemoglobin A1c.
  • Increased HDL (removes cholesterol buildup from arterial walls).

This stream of favorable data is causing testosterone prescriptions to surge. From 1994 to 2004, prescription sales of testosterone increased by 500%.103 We believe they have grown substantially more than that since then, especially when considering that sales of low-cost compounded testosterone creams are not easily counted in the official statistics.

It is regrettable that despite compelling findings of profound efficacy, some conventional doctors still question the value of testosterone replacement in maturing men. This oversight is causing too many needless heart attacks.

For nearly 20 years, Life Extension has urged its male members to restore testosterone levels to youthful ranges. We have written meticulous rebuttal to media attacks that question the value of properly-prescribed natural testosterone.

George W. Bush’s Blocked Coronary Artery

George W. Bush
Former President
George W. Bush

George W. Bush (the younger Bush) may have been the first President to describe his daily health routine that included regular exercise along with a multivitamin, low-dose aspirin, and possibly some fish oil. Former President Bush had annual physical exams by the government’s best doctors.

In August 2013, doctors discovered that a vital coronary artery in George W. Bush was 95% blocked. An emergency stent was inserted to restore blood flow through the occluded artery. According to medical sources, the location and severity of the coronary artery blockage usually causes sudden death and the former President was lucky his doctors caught it in time.105

We are seeking the medical records of President Bush through the Freedom of Information Act, but we are confident that his annual “Presidential” exams did not include the comprehensive blood testing that Life Extension members take each year. As we long ago documented, all it takes is for one independent vascular risk factor to be out of safe range for a heart attack, stroke or kidney failure to ensue.106-108

Vascular disease was the cause of death of former Presidents Franklin Roosevelt, Harry Truman, Dwight Eisenhower, Lyndon Johnson, Richard Nixon and Gerald Ford. Eisenhower suffered horrifically from heart disease for over a decade before dying from congestive heart failure.109,110

In 2004, Bill Clinton underwent open heart surgery to bypass multiple blocked arteries in his heart that would have likely killed him in a few months if not treated.111 He had to undergo follow-up surgery in 2005 to correct a complication caused by his first bypass surgery.112

In 2010, Clinton was rushed to the hospital complaining of chest pains and had two stents implanted to open two new occluded coronary arteries. Clinton regularly exercised, but did little else other than what his conventional doctors prescribed. Clinton’s program obviously failed to protect him from severe and recurring coronary atherosclerosis.113

Dick Cheney’s Multiple Heart Attacks

Dick Cheney
Former Vice President
Dick Cheney

In this month’s issue, we feature a review of a book authored by former Vice President Dick Cheney.116 Perhaps no living political figure better exemplifies what happens to one’s arteries in response to poor lifestyle choices than Dick Cheney.

Cheney was known for eating outrageous quantities of artery-clogging foods and smoking heavily for 20 years.

Dick Cheney suffered his first heart attack in 1978, when he was only 37. He suffered his second in 1984 and a third in 1988 before undergoing a quadruple bypass surgery to unblock his clogged arteries. His fourth heart attack occurred in 2000. At that time, doctors inserted a stent to open a re-occluded coronary artery.

In 2001, doctors implanted a device to track and control Cheney’s heart rhythm. In 2008, he underwent a procedure to restore his heart to a normal rhythm after doctors found that he was experiencing a recurrence of atrial fibrillation. Despite all this, Cheney suffered his fifth heart attack in February 2010.

Dick Cheney has reportedly taken statin drugs for nearly two decades. In June 2001, his LDL was an excellent 72 mg/dL, indicating he was taking a high-dose statin drug. This did not, however, prevent him from suffering another heart attack.

The former Vice President has had access to the best that conventional cardiology can offer, yet his chronic heart ailments did not abate until he received a heart transplant in 2012.

Don’t Be Victimized By Overwhelmed Doctors

We at Life Extension have new members send us their blood test results for our review. It never ceases to amaze us as to how many important blood tests such as C-reactive protein, hemoglobin A1c, homocysteine, and vital hormones are omitted.

Tom Frieden, MD, MPH  

Standard blood panels today look at lipids (cholesterol, LDL, HDL, triglycerides) and glucose. If levels of these vascular risk markers are within conventional “reference ranges,” then the patient is told they are fine.

One big mistake that people make is thinking that being in the “reference range” means they are safe. For instance, a doctor may look at your fasting glucose reading of 97 mg/dL and say you have no diabetic problems. If you happen to be over-secreting large amounts of insulin that keeps your glucose suppressed, then you are facing diabetic complications that can adversely impact every part of your body. A hemoglobin A1c test is a far more accurate measure of glucose control. Fasting glucose levels should be below 86 mg/dL and hemoglobin A1c below 5.6%.)122,123

With restrictions being placed on healthcare expenditures, aging Americans are being denied the opportunity to protect their circulatory system against atherosclerosis. Doctors facing a surge of newly insured patients under the Affordable Care Act are less able to spend the time to evaluate comprehensive blood test results. It is up to the individual to take charge of their health and longevity by having annual blood tests and following up on any reading that is out of optimal range.

Life Extension’s Common Sense Approach

A meticulous review of the scientific literature reveals a multitude of factors that cause humans to accumulate atherosclerotic plaque. Validated blood markers are available to identify specific vascular risks so that corrective actions can be taken before a heart attack or stroke strikes.

Yet this scientific approach to disease prevention is tragically overlooked by today’s hurried medical establishment.

Life Extension retails a comprehensive Male and Female Blood Test Panel for $400. This is a fraction of the price most commercial labs charge for all of these tests you can see outlined on the next page.

Once a year, we sharply discount the member price of the Male or Female Panels to $199. This enables Foundation members to gain control over their medical destiny and initiate meaningful changes before acute or chronic disease ensues.

With increasing insurance deductibles and co-pays, obtaining a comprehensive Male or Female Panel represents a huge economic value. Discovering correctable disease factors not only spares suffering and premature death, but could save tens of thousands of dollars in medical outlays that may not be covered by health insurance.

Elevated Glucose Kills After People Are Hospitalized
Elevated Glucose Kills After People Are Hospitalized

Higher hospital admission glucose levels have been shown in several studies to predict increased risk in heart attack patients.117-119 Data also suggest that elevated hemoglobin A1c is associated with an increased risk of cardiovascular disease, even in patients without diabetes.120

For example, a study published in 2013 showed that combined admission glucose and hemoglobin A1c values were independently associated with adverse clinical outcomes in non-diabetic patients with acute coronary syndrome treated with coronary stents or other interventions.121

The take-home message is that glucose need not reach diabetic levels (above 125 mg/dL) to inflict deadly consequences. Optimal fasting glucose levels are below 86 mg/dL.

How Easy It Is To Get Tested…

You can order the Male Panel or Female Panel at these discounted prices by making one phone call to 1-800-208-3444 (24 hours).

Within a few days you’ll receive a listing of blood drawing stations in your neighborhood. Appointments are usually not necessary, meaning you can have your blood drawn at your convenience.

With today’s modern technology, your results come back fast. If you have any questions, you can phone or email our health advisors 7-days a week.

I am often asked what are the most important nutrients, hormones or age-delaying drugs to take. My steadfast answer is that I have no idea what is most important for YOU until I see results from a comprehensive blood test panel.

It does little good to protect your body from say oxidized LDL if your homocysteine and C-reactive protein levels are elevated…or you’re unwittingly taking a drug that is slowly destroying your kidneys or liver.

The Male and Female Blood Test Panels provide a wide range of blood markers to reduce the risk that an insidious minor disorder will someday inflict permanent damage in you.

To order these comprehensive blood test panels at the year’s lowest prices, call 1-800-208-3444 today.

For longer life,

For Longer Life

William Faloon

Male and Female Blood Test Panels

Unlike commercial blood tests that evaluate only a few disease risk factors, Life Extension’s Male and Female Blood Test. Panels measure a wide range of blood markers that predispose people to common age-related disorders. Just look at the huge number of parameters included in the Male and Female Blood Test Panels:

MALE PANEL FEMALE PANEL

Lipid Profile

Total Cholesterol
LDL (low-density lipoprotein)
HDL (high-density lipoprotein)
Triglycerides

Cardiac Markers

C-Reactive Protein (high sensitivity)
Homocysteine

Hormones

Free and Total Testosterone
DHEA-S
Estradiol (an estrogen)
TSH (thyroid function)
Vitamin D (25-hydroxyvitamin D)

Metabolic Profile

Glucose
Kidney function tests: creatinine, BUN, uric acid, BUN/creatinine ratio
Liver function tests: AST, ALT, LDH, GGT, bilirubin, alkaline phosphatase
Blood minerals: calcium, potassium, phosphorus, sodium, chloride, iron
Blood proteins: albumin, globulin, total protein, albumin/globulin ratio
Hemoglobin A1c

Complete Blood Count (CBC)

Red Blood Cell count including: hemoglobin, hematocrit, MCV, MCH, MCHC, RDW
White Blood Cell count including: lymphocytes, monocytes, eosinophils, neutrophils, basophils
Platelet count

Cancer Marker

PSA (Prostate Specific Antigen)

Lipid Profile

Total Cholesterol
LDL (low-density lipoprotein)
HDL (high-density lipoprotein)
Triglycerides

Cardiac Markers

C-Reactive Protein (high sensitivity)
Homocysteine

Hormones

Progesterone
DHEA-S
Free and Total Testosterone
Estradiol (an estrogen)
TSH (thyroid function)
Vitamin D (25-hydroxyvitamin D)

Metabolic Profile

Glucose
Kidney function tests: creatinine, BUN, uric acid, BUN/creatinine ratio
Liver function tests: AST, ALT, LDH, GGT, bilirubin, alkaline phosphatase
Blood minerals: calcium, potassium, phosphorus, sodium, chloride, iron
Blood proteins: albumin, globulin, total protein, albumin/globulin ratio
Hemoglobin A1c

Complete Blood Count (CBC)

Red Blood Cell count including: hemoglobin, hematocrit, MCV, MCH, MCHC, RDW
White Blood Cell count including:
lymphocytes, monocytes, eosinophils, neutrophils, basophils
Platelet count

Non-member retail price: $400 • Special Member Discount Price: $199.
Blood Test Super Sale — March 31st through June 2, 2014.
To obtain these comprehensive Male or Female Panels at these low prices,
call 1-800-208-3444 to order your requisition forms.
Then—at your convenience—you can visit one of the blood-drawing facilities provided by LabCorp in your area.
(Restrictions apply in NY, NJ, RI, MA, MD, PA)