Life Extension Magazine













Anti-Aging Medicine Conference Is Huge Success


Anti-Aging Medicine Conference Is Huge Success - Life Extension Events, March 1, 1995 (in Life Extension Magazine, No. 5, March 15, 1995) This is the first issue of Life Extension Events (LEE)-a newsletter that will INFOrm you about upcoming conferences, seminars, and meetings of interest to life extensionists, and will present reviews of some of these events. Members of The Life Extension Foundation
will be able to obtain substantial discounts on admission prices to these events, as well as discounts on the proceedings of the events. In this initial issue of LEE, we present a review of the recent Anti-Aging Medicine Conference in Las Vegas, and present you with an opportunity to purchase exclusive video-tapes of the conference.

The big tent rising into the sky was the most noticeable sign of success. It was put up by Life Extension Foundation member Louis Habash, the owner of the Alexis Park Resort in Las Vegas, to handle the overflow crowd at the 2nd Annual Conference on Anti-Aging Medicine & Biomedical Technology for the Year 2010 on Dec. 4-6, 1994.

The second most noticeable sign of success was Ed Bradley of 60 Minutes wandering around with a camera crew, conducting interviews with doctors and scientists. The 60 Minutes crew was only one of a half-dozen or so TV crews covering the conference.

Finally, there were the people themselves. About 1,100 life extensionists from every corner of the U.S. and abroad (19 countries)...gathered together to learn about therapies to control aging, and to celebrate the quest for a longer, healthier life.

A Highly-Charged Atmosphere

From the moment the conference began, the atmosphere at the Alexis Park crackled with the electric thrill and menace of a decisive moment... of a path-breaking event signalling the dawning of a new era. It was the first time in history that so many medical doctors, gerontologists, and members of the lay public gathered together to proclaim the value of anti-aging medicine in pursuit of an extended healthy lifespan.

At every opportunity, Dr. Ronald Klatz, President of the American Academy of Anti-Aging Medicine (the sponsor of the event) reminded the audience of its momentous nature. Of the realization that many members of the medical community had finally come out of the closet to pursue therapies aimed at slowing, stopping, and reversing human aging, and to admit that they themselves are personally interested in life-extension therapies.

The Medicine Of The 21st Century

Dr. Robert M. Goldman, President of the National Academy of Sports Medicine, and co-organizer of the conference (with Dr. Klatz), spoke about how anti-aging medicine is "the future of medical practice" and how it "allows both the medical professional and patient to have control over their personal health and well being and the quality of their fitness and life functions."

Today, proclaimed Dr. Goldman, "we have 70 year olds with the bodies of those less than half their age," and with the progression of this landmark science, we'll see ever-healthier and more youthful people at increasingly advanced ages. As he put it: "Anti-Aging Medicine is the future of medical practice. It encompasses all specialties and fields. It can be accessed and utilized by everyone."

Honoring The Pioneers

One of the features of the conference was the heartfelt acknowledgement of the pioneering efforts of scientists who have been conducting life extension research for decades. Among those in attendance who were honored for their historic efforts in the field were Richard G. Cutler, Ph.D. of the Gerontology Research Center in Baltimore and Roy M. Walford, M.D. of the UCLA Medical Center in Los Angeles.

Several speakers mentioned that-since the 1970s-Dr. Cutler has been the only scientist in the federal government (National Institute On Aging) who has dared to speak openly to outsiders about extending the human lifespan. Now-finally-others in the government are beginning to speak out about the desirability of a longer, healthier lifespan as a national goal.

At the conference, Dr. Cutler spoke about life extension concepts he's been developing for many years and the findings he's generated in support of these concepts. Among them is the idea that aging begins when differentiated organs and systems go awry (the Dysdifferentiation Hypothesis Of Aging); that Oxidative Stress exacerbates the process; that Health Maintenance Processes have evolved to protect us against aging and disease processes; and that Longevity Determinant Genes, such as the gene that controls superoxide dismutase act to maintain and extend our healthspan.

An Unplanned Calorie Restriction Experiment

Dr. Roy Walford has conducted considerable research showing that maximum lifespan in mice can be extended significantly (even in middle-age) by feeding the mice a low-calorie, high-nutrient diet. Dr. Walford has also extended lifespan in cold-blooded animals by reducing their body temperature, and is the foremost proponent (in his book The 120-Year Diet) of calorie restriction in humans as a means of extending lifespan. (Some of the members of a calorie-restriction club [inspired by Walford] were in attendance at the conference).

Dr. Walford was the featured speaker at the banquet on the evening of the second day of the conference (Dec. 5). He explained (with the help of startling photographs) how the eight inhabitants (including himself) of the closed ecologic space known as Biosphere-2 underwent an unplanned two-year experiment in calorie restriction because they couldn't grow as much food as anticipated.

Dr. Walford's studies of the inhabitants of Biosphere-2 provide evidence that humans on a calorie-restricted, nutrient-dense diet show the same beneficial physiological changes in cholesterol levels, fasting blood sugar, blood pressure, white blood cell counts, glycated hemoglobin, and insulin and cortisol levels as rodents on such a diet in the laboratory. This strengthens the inference, contends Dr. Walford, that such a diet may increase resistance to disease and retard the aging process.

Dr. Walford acknowledged that calorie restriction is probably not applicable to a general population, but that the rapid advances now being made in gerontology, suggest that other simpler methods of life extension are forthcoming, and that the 21st century will be the century of "the long living society."

Current Anti-Aging Therapies

A good number of the speakers and many private discussions at the conference involved currently-used therapies for which there is evidence of anti-aging effects. The fact that there were an unprecedented number of researchers and users of such therapies at the conference led to especially fruitful discussions on the potential benefits and side effects of such therapies as deprenyl, DHEA, melatonin, centrophenoxine, growth hormone, and others.

Anti-Aging Effects Of Deprenyl

Research findings on the popular anti-aging drug deprenyl were presented by scientists from the University Of Toronto, Kansas State University, and Tokyo Metropolitan Institute Of Gerontology in Japan through several presentations at the Poster Session and a featured talk by Toronto scientist Gwen Ivy, who summarized the major findings on the effects of deprenyl on lifespan and cognitive function in animals.

Dr. Ivy stated that she and her colleagues have been conducting lifespan experiments with deprenyl ever since Hungarian scientist Joseph knoll reported that he had extended the lifespan of middle-aged (24-month-old) laboratory rats by 200% by giving them injections (0.25 mg/kg 3 times a week) of deprenyl.

The Toronto scientists found that they could achieve only modest lifespan increases with deprenyl (16%-33%). However, they've also found effects of deprenyl that may help to explain the drug's ability to extend lifespan, including the fact that deprenyl-in addition to selectively inhibiting the aging enzyme monoamine oxidase B-also increases the levels of the free-radical scavenging enzymes superoxide dismutase and catalase; the fact that deprenyl can rescue neurons that would otherwise die from exposure to neurotoxins; and the fact that deprenyl promotes the synthesis and release of growth factors involved in tissue repair and immunologic function.

L-Deprenyl Improves Long-Term Memory

In Aged Dogs

One of the most recent findings about deprenyl reported at the conference is its ability to significantly improve the short-term memory of aged (16-year-old) beagles (but not young beagles) tested on their ability to remember learned spatial tasks after delays of 20, 70, and 110 seconds. The best results came with aged dogs who had received deprenyl and were tested after a 110-second interval. The scientists also found that the decline in immune response in aged dogs was restored after treatment with deprenyl.

DHEA-The "Mother" Steroid

One of the most talked about anti-aging therapies at the conference was DHEA-the adrenal steroid that declines precipitously with advancing age, and which has been shown to be beneficial for a wide variety of diseases. In fact, the title of Dr. William Regelson's talk about DHEA was "the 'mother' steroid" because of DHEA's role as "parent" to steroid hormonal mediators in the pathway to steroid synthesis. Dr. Regelson suggested that "DHEA may be considered a buffer steroid, which modulates corticosteroid action to decrease stress, or to affect other endocrine events...without specific organ targeted effects, in a manner analogous to the action of thyroid hormone."

As a longtime DHEA researcher at the University of Virginia Medical Center, who has written several articles on DHEA, Dr. Regelson provided a thorough review of research showing that DHEA is a neurosteroid, immunomodulatory agent, insulin enhancer, anti-cancer agent, and anti-aging therapy.

DHEA Replacement Therapy

Dr. Julian M. Whitaker of the Whitaker Wellness Institute in Newport Beach, California-a pioneer in alternative medicine-discussed the therapeutic benefits of DHEA. Dr. Whitaker revealed the potential of DHEA therapy for cardiovascular disease, diabetes, hypercholesterolemia, cancer, Alzheimer's disease, obesity, memory deficits, autoimmune diseases, AIDS, chronic fatigue, and osteoporosis. He mentioned that-in the treatment of these diseases-doses of DHEA as high as 1,600 mg a day have been given for up to a month without side effects.

Dr. Whitaker gave special attention to restoration of youthful DHEA levels in aging persons. He pointed to research showing that an increase in blood levels of DHEA sulfate (the form of DHEA found in the blood) has been associated with a 36% reduction in mortality from all causes. According to Dr. Whitaker, a recommended initial therapeutic dose for DHEA replacement therapy is "25 mg/day for women and 50 mg/day for men, with monitoring of blood levels every three months and adjusting the dose accordingly." (Other physicians recommend initial doses of 100 mg. a day of DHEA and higher for people with very low DHEA serum levels.)

Multiple Hormone Replacement Therapy

Dr. Ronald L. Hoffman of the Hoffman Center in New York city emphasized that attempts at hormone replacement therapy as a means of slowing or reversing aging may be counterproductive unless multiple replacement therapies are used to avoid "creating system imbalance." According to Dr. Hoffman, the body's hormones interact in a highly complex manner that can easily be disturbed by imbalances in activity.

Dr. Hoffman discussed various forms of hormone replacement therapy to retard aging including: estrogen and progesterone, testosterone, DHEA, thyroid hormone, growth hormone, and melatonin.

He paid special attention to Melatonin by referring to "a mysterious gland that may play the most important role of all in 'pacing' the aging process: the pineal. Studies of Melatonin administration in animals show that it has a profound life-extending effect."

The Most Affordable Anti-Aging Therapy

William Faloon of the Life Extension Foundation pointed out that Melatonin is not only a highly promising anti-aging therapy, but is also less expensive than other such therapies. If purchased from The Foundation's Life Extension Buyers' Club, Melatonin costs only $4.00-$8.00 per month for a daily 3-6 mg. replacement dose every night.

To give the audience an idea of the extensive research results published on melatonin, Faloon held up the recent 588-page book published by the New York Academy Of Sciences, which includes 15 new papers on Melatonin as well as papers on DHEA and other anti-aging therapies. (The findings in this book were summarized in the Nov. issue of Life Extension Update)

Faloon also pointed out that the prohibitive cost of hormone replacement therapies such as growth hormone, DHEA, and thymosin, which forces some Foundation members to spend as much as $25,000 a year on them, and makes it impossible for many members to obtain their full benefits, is caused in large part by excessive FDA regulation and enforcement action.

The Anti-Cortisol Therapies

One of the disastrous effects of FDA enforcement is the agency's efforts to prevent Americans from enjoying the benefits of unapproved anti-aging therapies such as Gerovital-H3 (GH3) and K.H.3-two procaine formulas which have been readily available throughout the world for decades, and which have been used with great safety by millions of people as a treatment for many of the disorders of aging including depression, age-related dementia, short-term memory loss, diabetes, osteoporosis, atherosclerosis, hair graying and hair loss, as well as for the prevention of aging-related disorders!

GH3 and K.H.3 are weak, reversible inhibitors of the enzyme monamine oxidase (MAO), which produce anti-aging benefits without the side effects associated with other MAO inhibitors. However, the most important anti-aging effect of these therapies may be their ability to counter the deleterious effects of cortisol-the corticosteroid hormone believed to be involved in a variety of stress-related diseases of aging.

Treating Memory Loss In Alzheimer's Patients

Dr. Dharma Singh Khalsa, President of the Alzheimer's Prevention Foundation/Brain Longevity Institute in Tucson, Arizona reported (at the conference) that the greatest obstacle to their search for new ways of preventing and reversing memory loss is "chronic unbalanced stress which, via the release of the hormone cortisol, is an accelerator of aging in both body and mind."

Dr. Khalsa said that-in both rat and human studies-cortisol-induced stress has been shown to produce memory dysfunction in three ways:

"1) cortisol prevents the uptake of glucose by the hippocampus

2) cortisol inhibits synaptic transmission

3) cortisol leads to neuron injury and cellular death"

Dr. Khalsa's "reversal" program includes vitamins, cerebral tonifying herbs, drugs such as deprenyl, deferoxamine (a metal chelator), DHEA, nootropic medications (such as piracetam), and simple meditation. Among the other therapies shown to improve memory (and behavior) in Alzheimer's patients are the anti-cortisol therapies GH3 and K.H.3, acetyl-l-carnitine, phosphaditylserine, and tacrine (THA).

Coenzyme-Q10 And Lifespan Extension

Stephen Coles, M.D., Ph.D. of the Jet Propulsion Laboratory in Pasadena and Steven B. Harris, M.D. of the UCLA Medical Center in Los Angeles discussed recent research showing that high doses of coenzyme-Q10 (coQ10) (equivalent to hundreds of milligrams a day in humans) caused a significant increase in average lifespan in laboratory mice (without adverse side effects), but did not appear to increase maximum lifespan.

Coles and Harris pointed out that coQ10 has been shown to be highly effective in preventing and treating atherosclerosis, angina (heart pain), myocardial infarction (heart attack), and other cardiovascular diseases. Moreover, coQ10 is a highly effective anti-oxidant and is involved in energy production. The researchers presented slides showing that mice receiving coQ10 were far livelier and more youthful looking than control animals.

New Anti-Aging Therapies

One of the most established anti-aging drugs in the world (which has never been submitted for U.S. FDA approval) is centrophenoxine, which has been shown to improve memory, concentration, and energy levels in humans, and has extended lifespan in laboratory mice. One of the participants in the conference was the world's foremost centrophenoxine researcher, Dr. Imre Zs.-Nagy of the Fritz Verzar International Laboratory in Decebren, Hungary.

BCE-001: A New Analog Of Centrophenoxine

Dr. Zs.-Nagy revealed that he and his colleagues in Hungary have altered the chemical structure of centrophenoxine in order to develop a new anti-aging drug-(BCE-001-U.S. patent No. 4661618). In this new drug, one of the two components of centrophenoxine, dimethylaminoethanol (DMAE, an anti-aging drug in its own right) has been replaced by a new compound, 1,3-bis(dimethylamino)-2-propanol (BIDIP).

According to Dr. Zs.-Nagy, BCE-001 has been shown to be an effective nootropic agent of low toxicity, which can be injected or taken orally. He says it acts in a similar manner as centrophenoxine, but acts twice as fast at lower doses! Right now, BCE-001 is at the stage where clinical trials are necessary to test its effects in humans, but the Hungarian company that owns the rights to it does not have the money to develop BCE-001 further and is looking to sell its rights to the drug to another company.

A New Immunostimulant

One of the new therapies discussed at the conference by D.L. Busbee and associates of Texas A & M University in College Station, Texas is acemannanTM-a long-chain (1,4) linked acetylated polymannose (ACM). When mice who had developed tumors induced by the injection of sarcoma cancer cells were given injections of ACM (1 mg/kg in sterile 0.9% NaCl), "tumor regression and complete recovery were observed in 40% of the animals!

Tests showed that ACM treatment "increased IL-1 and IL-6 secretion in young and old animals...(that) cells from old ACM-treated mice showed almost a 2-fold increase in concanavalin-stimulated blastogenesis over cells from non-ACM-treated mice...and that ACM treatment was associated with increased capacity of animals to mount effective immune system surveillance against implanted sarcoma cells." It was concluded that "ACM is an effective immunostimulatory agent in mice...and that it might have a use in the long-term support of immune function in anti-aging medicine."

Acemannan is an active component of pharmaceutical-grade Aloe Vera extract. For INFOrmation on how to obtain Aloe Vera extract with the highest concentration of acemannan, call The Life Extension Foundation at 1-800-841-5433.

Genentech's New Therapy

One of the highlights of the conference was a talk by Grace Wong, Ph.D. of Genentech, Inc. in South San Francisco, California, in which she revealed the results of her research with an immune system cytokine called lymphotoxin (LT), which is produced within the body by a specific gene triggered by oxidative stress. According to Dr. Wong, "LT specifically and selectively induces the expression of the protective protein manganese superoxide dismutase (MnSOD), a mitochondrial enzyme that scavenges superoxide radicals. Over expression of MnSOD, but not copper or zinc SOD enhances cellular resistance to oxidative stress...LT does not induce MnSOD in tumor cells; nor does LT protect cancer cells against oxidative stress."

Dr. Wong reported that pretreatment with LT protects mice against a lethal dose of radiation that kills untreated mice, that LT helps mice injected with tumor cells survive, and that it protects mice against hair loss caused by exposure to toxic chemicals. When asked whether LT is available for humans, Dr. Wong said it is not, but that the gene for LT can be turned on by a state of "happiness" (she calls it the "happy gene") and that we can get some of the benefits of LT by simply "being happy".

Is SOD The Body's Own Anti-Aging Therapy?

Evidence is mounting that stimulation of intracellular superoxide dismutase (SOD) can slow aging and protect us against the diseases of aging. First is an experiment performed by Sohol and Orr of Southern Methodist University, in which the maximum lifespan of flies was doubled by insertion of a second SOD gene. Next we have Dr. Wong's findings that the ability of LT to stimulate MnSOD protects mice against radiation, cancer, and toxic chemicals. Then there is the finding by the University Of Toronto scientists that deprenyl-which has multiple anti-aging benefits-stimulates the release of SOD within the body.

It may be that the protective action of SOD represents one of the genetically controlled health maintenance processes suggested by Richard Cutler as being responsible for the length of the current human lifespan, and that stimulation of intracellular SOD by whatever means might help us to live in good health for extended periods of time. (Ingesting SOD supplements does not elevate intracellular SOD levels)

Future Anti-Aging Technologies

It was the general consensus at the conference that major breakthroughs in anti-aging medicine are on the horizon from ongoing advances in genetics and genetic engineering. There was considerable talk about recent discoveries by scientists at Geron Corporation in Menlo Park, California that the integrity of our chromosomes is maintained by structures at their tips called telomeres; that progressive shortening of our telomeres during each bout of cell division leads to cellular senescence and death, and that the key to rebuilding our telomeres is the enzyme telomerase, which is absent in normal human cells (except for germ cells), but is found in cancer cells, which continue to divide indefinitely. (We'll be carrying an update on Geron in the near future in LIFE EXTENSION MAGAZINE.

Geron was not represented at the conference, but there was a talk (and poster) by Don Kleinsek, Ph.D. of GeriGene Medical Corporation in Elkhart, Wisconsin, which is seeking to develop anti- aging genetic therapies. Dr. Kleinsek says that GeriGene has in development "anti-aging molecules for arthritis, osteoporosis, cancer, skin aging and artificial skin renewal, wound healing, cell death, and viral diseases. (We'll be carrying a story about GeriGene in LIFE EXTENSION MAGAZINE in the near future).

New Drug Delivery Systems

One of the major obstacles to the development of better anti-aging therapies is the primitive nature of today's drug delivery systems. In the vast majority of cases, today's drugs are delivered orally through pills and capsules or through injections. The problem with these systems is that they must deliver enough drug to last for 4-to-24 hours, depending upon how often you take (or are given) the drug. This means that, upon administration of the drug, your body is flooded with a very large amount of drug, which raises your blood levels well above optimal to cause unwanted side effects. Your body is then depleted of the drug prior to the next time you take it, thereby reducing its therapeutic effects.

There are now advanced systems, which deliver the precise amount of drugs continuously-through the skin, through true time-release oral systems, and through implanted time-release systems to provide the body with a steady-state therapeutic level of the drug. Such systems provide safer and more effective therapy than the zigzag drug delivery patterns of today's systems, but are still far more primitive than the body's own delivery systems (such as your endocrine glands), which adjust their release of hormones, enzymes, and other internal "drugs" on a continuous basis.

At the conference, Dr. Vincent C. Giampapa of the University Of Medicine and Dentistry of New Jersey discussed the development of "subcutaneous implantable pod systems" capable of delivering multiple drugs at desired time sequence intervals. Eventually, this type of system will permit the kind of multiple hormone replacement necessary to restore youthful levels of critical hormones in a physiologically balanced manner.

The Promise Of Nanotechnology

Since diseases, injuries, and aging are caused by damage at cellular and molecular levels, the ultimate method of repairing damage from these sources is likely to be molecular machines controlled by computers, which are far smaller than cells. Such machines will be able to enter our cells to repair damage that our own repair systems cannot deal with, and even to replace natural repair systems which have been irretrievably damaged as a result of aging.

Such highly-sophisticated systems should, eventually, be able to repair even very severe damage to cells, tissues, and organs by inferring the appropriate changes necessary to restore healthy structure and function based upon an accurate reading of the remaining intact structures combined with detailed knowledge of how such structures are put together.

The development of molecular level medical technology will be the natural outgrowth of a new science known as nanotechnology, which involves engineering on a nanometer level (a billionth of a meter). At the conference, Ralph Merkle, Ph.D., who conducts nanotechnology research at the Xerox Palo Alto Research Corporation in California, reviewed the current status of this new field and suggested how 21st century physicians might employ nanotechnology to enable us to become physically immortal.

Obtaining Videotapes Of The Conference

You can now obtain exclusive videotapes of the recent Anti-Aging Medicine Conference from the Life Extension Foundation. The following tapes of the conference are available at discount prices for Foundation members:

I - Highlights Of The 1994 Anti-Aging Medicine Conference - A one-hour review of the many talks given at this historic event by many of the foremost authorities on anti-aging medicine in the world interspersed with clips that give the flavor and atmosphere of this truly exciting event. The retail price of a copy of this highlight tape costs $49.95. Members can purchase it for only $24.95.

II - Tapes Of The Individual Presentations At The 1994 Anti-Aging Medicine Conference - The retail price of each of these tapes is $39.95. Members can purchase them for only $19.95 each. The total retail price for all the conference tapes is $449.95. Members can purchase all of the tapes for only $239.95.

You can purchase these tapes by calling The Foundation's toll-free number: 1-800-841-5433

or by sending your check or money order (add $4.00 for postage and handling) to:

The Life Extension Foundation

Box 229120

Hollywood, FL 33022.

The following conference tapes are available from The Foundation:

1. Roy Walford, M.D. - Life Extension Now And In The 21st Century

2. Richard Cutler, Ph.D. - Extension Of Lifespan:theory And Facts

3. Julian Whiitaker, M.D. - DHEA As A Marker Of Aging And A Therapeutic Principal

4. William Regelson, M.D. - DHEA: The Mother Steroid

5. Grace Wong, Ph.D. - Lymphotoxin And Oxidative Stress

6. Stephen Coles, M.D., Ph.D. and Steve Harris, M.D. - Co-Enzyme Q10 And Lifespan Extension

7. Gwen Ivy, Ph.D. - L-Deprenyl And Its Anti-Aging Effects

8. Ronald Hoffman, M.D. - Hormones And Aging

9. Robert Goldman, D.O., Ph.D. - Anti-Aging Medicine: The Future Of Medical Practice

10. Robert Morin, M.D. - Prevention And Reversal Of Atherosclerosis

11. James Wilson, Ph.D. - The Use Of Thymus Extracts As An Exogenous Factor in Immunosenescence And A Mediator Of Chronic Disease

12. Vincent Giampapa, M.D. - New Concepts in Drug Delivery Systems

13. Don Kleinsek, Ph.D. - Gene Therapy: A Ten Year Forecast

14. Ralph Merkle, Ph.D. - Nanotechnology And Medicine

15. Ronald Klatz, D.O. - Predictions For The Year 2010

The Big Tent

The big tent was the center of attraction at the 1994 conference. It was a rapidly-constructed arena of ideas...where doctors, scientists, and journalists presented their data and words of wisdom-with large screens on both sides of the stage to display their slides and videos. The tent was erected because there wasn't a conference room in the hotel large enough to handle the 1,100 people who attended this historic event.

On one side of the tent was a large INFOrmal registration area adjacent to the lobby, where sweet rolls, bagels, muffins, orange juice, and other drinks were available throughout the morning, and fruit and cheese were served later in the day...and where people could gather together INFOrmally to exchange INFOrmation and ideas and to enjoy each others company.

A path to the right led to the exhibit hall where approximately 20 companies and organizations-including The Life Extension Foundation-had set up booths to provide attenders with free INFOrmation and personalized answers to questions about their products and services.

To the left of the tent was a large pool, which will be covered over to provide extra space to accommodate the much larger crowd expected at the next (1995) conference. Beyond the pool was a picturesque walkway leading through finely landscaped grounds (on both sides) to hundreds of comfortable, single-bedroom suites. (More than 300 additional people who wanted to attend the conference couldn't do so because there was only room for 1,100 people in the tent).

The Next Conference

The next Anti-Aging Medical Conference (1995) is being planned for the same time of year (early December) and is likely to be held again at the Alexis Park Resort, although final arrangements have not yet been made. We expect to announce the dates of the 1995 Anti-Aging Medicine Conference in the next issue of Life Extension Events. At that time, we'll also announce the registration fee and the discounts for Foundation Members. Anyone who wants more INFOrmation about becoming a member of the American Academy Of Anti-Aging Medicine (A4M) should:

Phone the Academy at: 1-312-975-4034 or write to:

American Academy of Anti-Aging Medicine

P.O. Box 146571

Chicago, IL 60614






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