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New Autism Data Have Been Reported by Investigators at University of Naples Federico II


By a News Reporter-Staff News Editor at Genomics & Genetics Weekly -- Current study results on Autism have been published. According to news reporting out of Naples, Italy, by NewsRx editors, research stated, "Autism spectrum disorders (ASD) are disorders of the central nervous system characterized by impairments in communication and social reciprocity. Despite thousands of studies on this topic, the etiopathogenesis of these disorders remains unclear, apart from a general belief that they derive from an interaction between several genes and the environment."

Our news journalists obtained a quote from the research from the University of Naples Federico II, "Given the mystery surrounding the etiopathogenesis of ASD it is impossible to plan effective preventive and treatment measures. This is of particular concern due to the progressive increase in the prevalence of ASD, which has reached a figure as high as 1:88 children in the USA. Here we present data corroborating a novel unifying hypothesis of the etiopathogenesis of ASD. We suggest that ASD are disorders of the immune system that occur in a very early phase of embryonic development. In a background of genetic predisposition and environmental predisposition (probably vitamin D deficiency), an infection (notably a viral infection) could trigger a deranged immune response which, in turn, results in damage to specific areas of the central nervous system. If proven, this hypothesis would have dramatic consequences for strategies aimed at preventing and treating ASD."

According to the news editors, the research concluded: "To confirm or refute this hypothesis, we need a novel research approach, which unlike former approaches in this field, examine the major factors implicated in ASD (genetic, infections, vitamin D deficiency, immune system deregulation) not separately, but collectively and simultaneously."

For more information on this research see: Etiopathogenesis of autism spectrum disorders: Fitting the pieces of the puzzle together. Medical Hypotheses, 2013;81(1):26-35. Medical Hypotheses can be contacted at: Churchill Livingstone, Journal Production Dept, Robert Stevenson House, 1-3 Baxters Place, Leith Walk, Edinburgh EH1 3AF, Midlothian, Scotland. (Elsevier -; Medical Hypotheses -

Our news journalists report that additional information may be obtained by contacting I. Gentile, University of Naples Federico II, Dept. of Med Translat Sci, I-80131 Naples, Italy (see also Autism).

Keywords for this news article include: Italy, Naples, Europe, Autism, Genetics, Neurology, Developmental Disabilities

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