By a News Reporter-Staff News Editor at Gastroenterology Week -- Investigators publish new report on Weight Loss. According to news originating from Lawrence, Kansas, by NewsRx correspondents, research stated, "Weight gain is an important risk factor for gastroesophageal reflux disease (GERD); however, whether weight loss can lead to resolution of GERD symptoms is not clear. Our aim was to measure the impact of weight loss on GERD symptoms."
Our news journalists obtained a quote from the research from the University of Kansas, "In a prospective cohort study at a tertiary referral center, overweight/obese subjects (BMI 25-39.9 kg/m2) were enrolled in a structured weight loss program. Weight loss strategies included dietary modifications, increased physical activity and behavioral changes. At baseline and at 6 months, BMI and waist circumference were measured and all participants completed a validated reflux disease questionnaire. A total of 332 adult subjects, mean age 46 years and 66% women were prospectively enrolled. At baseline, the mean body weight, BMI, and waist circumference were 101 (+/- 18) kg, 35 (+/- 5) kg/m2 and 103 (+/- 13) cm. At 6 months, majority of the subjects (97%) lost weight (average weight loss: 13 +/- 7.7 kg) and as compared with baseline, there was a significant decrease in the overall prevalence of GERD (15 vs. 37%; P< 0.01) and the mean GERD symptom score (1.8 vs. 5.5; P< 0.01). Overall, 81% of the subjects had reduction in GERD symptom scores; 65% had complete resolution and 15% had partial resolution of reflux symptoms. There was a significant correlation between % body weight loss and reduction in GERD symptom scores (r = 0.17, P< 0.05). In conclusion, the overall prevalence of GERD symptoms is high (37%) in overweight and obese subjects."
According to the news editors, the research concluded: "A structured weight loss program can lead to complete resolution of GERD symptoms in the majority of these subjects."
For more information on this research see: Weight Loss Can Lead to Resolution of Gastroesophageal Reflux Disease Symptoms: A Prospective Intervention Trial. Obesity, 2013;21(2):284-290. Obesity can be contacted at: Wiley-Blackwell, 111 River St, Hoboken 07030-5774, NJ, USA. (Nature Publishing Group - www.nature.com/; Obesity - www.nature.com/oby/)
The news correspondents report that additional information may be obtained from M. Singh, University of Kansas, Medical Center, Center Phys Activ & Weight Management, Dept. of Energy Balance, Lawrence, KS 66045, United States. Additional authors for this research include J. Lee, N. Gupta, S. Gaddam, B.K. Smith, S.B. Wani, D.K. Sullivan, A. Rastogi, A. Bansal, J.E. Donnelly and P. Sharma (see also Weight Loss).
Keywords for this news article include: Kansas, Lawrence, Acid Reflux, Weight Loss, United States, Esophageal Diseases, Deglutition Disorders, Gastroesophageal Reflux, North and Central America, Digestive System Diseases, Gastrointestinal Diseases, Esophageal Motility Disorders
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