Numerous Studies Show Mango's Potential Health-Affirming Properties
ORLANDO, Fla., Nov. 14, 2013 /PRNewswire/ -- Mangos are known for their
superfruit status and strong nutritional profile--bursting with antioxidants and
over 20 different vitamins and minerals, such as vitamin A, vitamin C, folate,
fiber, vitamin B6, and copper. But recent studies indicate that there's more to
mangos than just vitamins and minerals.
Mango Consumption Associated with Healthier Diets
A study published in The Journal of Nutrition and Food Sciences  suggests
that mango consumption is associated with a healthier diet. Researchers compared
the diets of more than 29,000 children and adults participating in the National
Health and Nutrition Examination Survey (NHANES) between 2001 and 2008. They
noticed adults who consume mangos tend to have a higher intake of certain
nutrients like potassium and dietary fiber, which help contribute to a balanced
Lower levels of C-reactive protein were found in adult mango-consumers.
C-reactive protein is a marker of inflammation and it has been suggested that
high levels of it in the blood may be linked to increased risk for heart
Compared to non-mango consumers, mango eaters, on average, had higher intakes of
whole fruit, vitamins C, potassium, and dietary fiber (in adults only) while
having lower intakes of added-sugars, saturated fats (in adults only), and
sodium (in adults only). Both adults and children who consumed mangos scored
higher on the Healthy Eating Index compared to those who did not eat mangos.
Mango Consumption Associated with Lower Blood Sugar Levels
Although more research is needed on the effects of mango consumption on human
health, emerging research suggests that mango consumption may help lower blood
sugar levels in obese adults. The pilot study  recently conducted by
researchers at Oklahoma State University (OSU) examined the effects of daily
mango consumption in obese individuals (twenty adults, 11 males and 9 females)
over a 12 twelve week time frame and found both male and female participants had
significantly lower blood sugar levels compared to their baselines; however
there were no significant changes to body composition for either gender.
These findings support the results from a previously published study 
conducted by the OSU researchers which found that adding 1% mango to high-fat
diets in mice was effective in reducing body fat accumulation and lowering blood
Although the mechanism by which mango exerts its effects warrants further
investigation, we do know that mangos contain a complex mixture of polyphenolic
compounds. Research has shown that several other plants and their polyphenolic
compounds, such as isoflavone from soy , epigallocatechin gallate from green
tea , and proanthocyanidin from grape seed , have a positive effect on
Some Polyphenolics in Mangos May Possess Cancer-Fighting Properties (In Vitro
Research published in the Journal of Agricultural and Food Chemistry  studied
the antioxidant polyphenols in mangos to help determine how these potential
anti-cancer bioactive compounds are broken down and absorbed. Such compounds,
which are ingested as part of the diet, help to protect normal body cells from
This preliminary research found that mango polyphenolics, particularly those
from Ataulfo and Haden cultivars, inhibited the growth of SW-480 colon cancer
cells by affecting pro-apoptotic genes and cell cycle control genes.
Preliminary Research on the Possible Effects and Correlation Between Mango and
Bone Density In Mice
A study  published in the Journal of Pharmacy and Nutrition Sciences examined
the effects of mango on bone mass and bone strength in high-fat diets in mice.
The researchers noted that both animal and human models have found that diets
high in saturated fat can impair bone mineralization and that some treatments
for chronic conditions such as diabetes can negatively impact bones. One example
is rosiglitazone, a drug used to lower blood glucose in patients with type 2
diabetes and associated with increased risk fracture risk and rapid bone loss in
both human and animal studies.
This research study found that mango supplementation helped counteract the
negative effects on bone parameters caused by a high-fat diet in mice. In
addition, mango supplementation may have improved glucose levels without the
side effects of bone loss that are associated with taking a blood glucose
lowering drug (rosiglitazone). The study also found that mice receiving high fat
diets supplemented with mango had better bone quality compared to than those
receiving rosiglitazone (those receiving the drug had the lowest bone mineral
Limitations and challenges to the study include determining the exact dose
(amount of mango) and identifying the bioactive compound and the possible
mechanism of action. The observed effects of mango may be attributed to
synergistic actions of different bioactive compounds and not just due to one
individual component. In addition, it is unclear whether the researchers would
see the same effects in humans and if this dose is reasonable for human
consumption. In humans, the 1% dose used in this animal study is equivalent to
eating approximately 10 grams per day of freeze dried mango (about 50-100 grams
of fresh fruit or half a fruit). More studies are needed to identify the
bioactive component(s) in mango and their mechanism(s) of action.
About The National Mango Board
The National Mango Board is a national promotion and research organization,
which is supported by assessments from both domestic and imported mangos. The
board was designed to drive awareness and consumption of fresh mangos in the
U.S. One cup of mango is only 100 calories, an excellent source of vitamins A
and C, a good source of fiber and an amazing source of tropical flavor.
Mango availability per capita has increased 32 percent since 2005 to an
estimated 2.47 pounds per year in 2012. Mango import volume for 2012 was 804
million pounds. Learn more at www.mango.org.
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nutrient intake, diet quality, and levels of some cardiovascular risk factors:
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Supported by the National Mango Board
 Evans S, Peterson S, Perkins-Veazie P, Clarke SL, Payton M, Smith BJ, Lucas
EA. Effects of mango supplementation on body weight and composition and clinical
parameters of obese individuals. Poster Presentation at Federation of American
Societies for Experimental Biology, 2013. Supported by the National Mango Board.
 Lucas EA, Li W, Peterson SK, Brown A, Kuvibidila S, Perkins-Veazie P, Clarke
SL, Smith BJ. Mango modulates body fat and plasma glucose and lipids in mice fed
a high fat diet. Br J Nutr. 2011;106(10):1595-505. Supported by the National
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DL, Hamrick MW, Baile CA. Genistein decreases food intake, body weight, and fat
pad weight and causes adipose tissue apoptosis in ovariectomized female mice. J
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Zucker rats fed a high-fat diet. Phytother Res. 2003 May;17(5):477-80.
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3-O-beta-D-glucoside-rich purple corn color prevents obesity and ameliorates
hyperglycemia in mice. J Nutr. 2003 Jul;133(7):2125-30.
 Norattor GD, Bertoldi MC, Krenek K, Talcott ST, Stringheta PC,
Mertens-Talcott SU. Anticarcinogenic effects of polyphenolics from mango
(mangifera indica) varieties. J Agri Food Chem. 2010, 58:4104-4112. Supported by
the National Mango Board
 Lucas EA, Brown A, Li Wenjia, Peterson SK, Wang Y, Perkins-Veazie P, Clarke
SL, Smith BJ. Mango modulates blood glucose similar to rosiglitazone without
compromising bone parameters in mice fed high fat diet. J Pharm Nutr Sci.
2012;2:115-126. Supported by the National Mango Board
SOURCE National Mango Board