By a News Reporter-Staff News Editor at Gastroenterology Week -- Current study results on Oncology have been published. According to news originating from Norwich, United Kingdom, by NewsRx correspondents, research stated, "To investigate whether the dietary antioxidants vitamins C and E, selenium and zinc decrease the risk of developing pancreatic cancer, for the first time using 7-day food diaries, the most accurate dietary methodology in prospective work. 23,658 participants, aged 40-74 years, recruited into the EPIC-Norfolk Study completed 7-day food diaries which recorded foods, brands and portion sizes. Nutrient intakes were calculated in those later diagnosed with pancreatic cancer and in 3970 controls, using a computer program with information on 11,000 foods."
Our news journalists obtained a quote from the research from the University of East Anglia, "Vitamin C was measured in serum samples. The HRs of developing pancreatic cancer were estimated across quartiles of intake and thresholds of the lowest quartile (Q1) against a summation of the three highest (Q2-4). Within 10 years, 49 participants (55% men), developed pancreatic cancer. Those eating a combination of the highest three quartiles of all of vitamins C and E and selenium had a decreased risk (HR=0.33, 95% CI 0.13 to 0.84, p<0.05). There were threshold effects (Q2-4 vs Q1) for selenium (HR=0.49, 95% CI 0.26 to 0.93, p<0.05) and vitamin E (HR=0.57, 95% CI 0.29 to 1.09, p<0.10). The HRs of quartiles for antioxidants, apart from zinc, were <1, but not statistically significant. For vitamin C, there was an inverse association with serum measurements (HR trend=0.67, 95% CI 0.49 to 0.91, p=0.01), but the threshold effect from diaries was not significant (HR=0.68, 95% CI 0.37 to 1.26). The results support measuring antioxidants in studies investigating the aetiology of pancreatic cancer."
According to the news editors, the research concluded: "If the association is causal, 1 in 12 cancers might be prevented by avoiding the lowest intakes."
For more information on this research see: Dietary antioxidants and the aetiology of pancreatic cancer: a cohort study using data from food diaries and biomarkers. Gut, 2013;62(10):1489-96. (BMJ Publishing Group - group.bmj.com/; Gut - gut.bmj.com/)
The news correspondents report that additional information may be obtained from P.J. Banim, Dept. of Medicine, University of East Anglia, Norwich, UK. Additional authors for this research include R. Luben, A. McTaggart, A. Welch, N. Wareham, K.T. Khaw and A.R Hart (see also Oncology).
Keywords for this news article include: Antioxidants, Europe, Norwich, Minerals, Oncology, Selenium, Chalcogens, United Kingdom, Gastroenterology, Pancreatic Cancer, Protective Agents, Pancreatic Neoplasms.
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