Fall Skin Care Sale

Researchers recreate antibody that kills HIV strains


Nation (Kenya)

03-05-14

Scientists in South Africa have mapped the evolution of an antibody that kills different strains of HIV, which might yield a vaccine for the incurable disease, the National Institute of Communicable Diseases said on Monday.

The scientists have been studying one woman's response to HIV infection from stored samples of her blood and isolated the antibodies that she developed, said Lynn Morris, head of the virology unit at the NICD.

The study, by a consortium of scientists from the NICD, local universities and the US Vaccine Research Centre of the National Institute of Allergy and Infectious Diseases, was published in the journal Nature.

Humans respond to HIV by producing antibodies to fight the virus. In most cases, the antibodies do not neutralise or kill different strains of the virus.

But a few known as "broadly neutralising antibodies" are able to break through a protective layer around the HIV virus and kill it.

ABLE TO CLONE ANTIBODIES

"The outer covering of HIV has a coating of sugars that prevents antibodies from reaching the surface to neutralise the virus.

"In this patient, we found that her antibodies had 'long arms', which enabled them to reach through the sugar coat that protects HIV," Penny Moore, one of the lead scientists, said in a statement.

The researchers had been able to clone the antibodies and would test if they were able to give immunity to a person without the virus, Morris said.

Human tests were at least two years away, she said.

"We are going to test them first on monkeys and if it works on monkeys we will go on to humans," she said.

South Africa carries the world's heaviest HIV/Aids case load with six million people infected with the virus, more than 10 per cent of the population.

This article was first published in the Business Daily.

Articles featured in Life Extension Daily News are derived from a variety of news sources and are provided as a service by Life Extension. These articles, while of potential interest to readers of Life Extension Daily News, do not necessarily represent the opinions nor constitute the advice of Life Extension.

  • Consumer Alerts | Learn about issues that could impact your right to obtain the nutritional supplements and/or hormones such as DHEA that you depend on.

  • LEF Forum | Life Extension hosts Forums on Supplements, Hormones, Lifestyles, Disorders/Diseases, and other areas of interest to life extensionists worldwide.

  • What's Hot | News flashes are posted here frequently to keep you up-to-date with the latest advances in health care, nutritional supplements, and longevity.

  • Legislative Action Center | Take action on important current issues featured in Life Extension magazine and our web site.

  • Events | Find out about upcoming life extension related conferences, seminars, and meetings, or view reports on past events.

  • Life Extension Update | Our periodical newsletter reports new findings in longevity, preventive medicine and disease as soon as they are discovered!

  • Multimedia Center | An information-packed collection of video and audio featuring various health topics of importance to you.

Get Your FREE Nutritional Supplement Guide