COLUMBUS, Ohio, Aug 18, 2008 (UPI via COMTEX) -- U.S. scientists say they've
used a spice-based compound as a starting point to develop synthetic molecules
able to kill cancer cells.
The Ohio State University researchers said they combined organic chemistry,
computer-aided design and molecular biological techniques to develop and test
pharmaceutical compounds that, in lab settings, are able to kill breast and
prostate cancer cells and stop them from spreading.
Assistant Professor James Fuchs said the synthetic molecules are derived from
curcumin, a naturally occurring compound found in the spice turmeric.
"Newer evidence describes how curcumin interacts with certain proteins to
generate anti-cancer activity inside the body," said Fuchs. "We're focusing on
the pathways that are most involved in cancer and trying to optimize for those
properties."
Fuchs presented the research Sunday in Philadelphia during the annual meeting of
the American Chemical Society.
URL: www.upi.com