By a News Reporter-Staff News Editor at Tuberculosis Week -- Research findings on Mycobacterium Infections are discussed in a new report. According to news reporting from La Jolla, California, by NewsRx journalists, research stated, "Low vitamin D levels in human immunodeficiency virus type-1 (HIV) infected persons are associated with more rapid disease progression and increased risk for Mycobacterium tuberculosis infection."
The news correspondents obtained a quote from the research from the University of California, "We report that physiological concentrations of 1?,25-dihydroxycholecalciferol (1,25D3), the active form of vitamin D, inhibits M. tuberculosis and HIV replication in co-infected macrophages through human cathelicidin microbial peptide-dependent autophagy that requires phagosomal maturation."
According to the news reporters, the research concluded: "These findings provide a biological explanation for the importance of vitamin D sufficiency in HIV and M. tuberculosis-infected persons, and provide new insights into novel approaches to prevent and treat HIV infection and related opportunistic infections."
For more information on this research see: Autophagy induction by vitamin D inhibits both Mycobacterium tuberculosis and human immunodeficiency virus type 1. Autophagy, 2012;8(10):1523-5 (see also Mycobacterium Infections).
Our news journalists report that additional information may be obtained by contacting G.R. Campbell, Dept. of Pediatrics, Division of Infectious Diseases, University of California San Diego, La Jolla, CA, United States.
Keywords for this news article include: La Jolla, HIV/AIDS, Virology, California, RNA Viruses, Retroviridae, United States, Actinobacteria, HIV Infections, Mycobacteriaceae, Gram Positive Rods, Vertebrate Viruses, Primate Lentiviruses, Mycobacterium Infections, Opportunistic Infections, North and Central America, Actinomycetales Infections.
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