By a News Reporter-Staff News Editor at Clinical Trials Week -- Fresh data on Laboratory Animals are presented in a new report. According to news originating from San Antonio, Texas, by NewsRx correspondents, research stated, "The extension of both median and maximum lifespan and the suppression of age-related diseases in laboratory animals by reduced food intake, i.e., calorie restriction (CR) are regarded as hallmarks of CR's anti-aging action. The diverse efficacy of CR to counteract aging effects and its experimental reproducibility has made it the gold standard of many aging intervention studies of recent years."
Our news journalists obtained a quote from the research from the University of Texas, "Although CR originally was used as a tool to perturb the aging process of laboratory animals as to uncover clues of underlying mechanisms of aging processes, current CR research interests have shifted to the retardation of aging-related functional decline and the prevention of age-related diseases. Advances in CR research on non-human primates and recent endeavors using human subjects offer a promising outlook for CR's beneficial effects in healthy human aging. In this review, several major issues related to CR's anti-aging mechanisms are discussed by highlighting the importance of modulating deleterious chronic inflammation at molecular levels and the impact of epigenetic chromatin and histone modifications by CR at the ultimate control sites of gene expression."
According to the news editors, the research concluded: "The recent research on rapamycin as a CR mimetic is summarized and a brief description of intermittent feeding patterns is reviewed in comparison to the CR effect."
For more information on this research see: Recent advances in calorie restriction research on aging. Experimental Gerontology, 2013;48(10):1049-1053. Experimental Gerontology can be contacted at: Pergamon-Elsevier Science Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, England. (Elsevier - www.elsevier.com; Experimental Gerontology - www.elsevier.com/wps/product/cws_home/525468)
The news correspondents report that additional information may be obtained from K.W. Chung, Univ Texas Hlth Sci Center San Antonio, Dept. of Physiol, San Antonio, TX 78229, United States. Additional authors for this research include D.H. Kim, M.H. Park, Y.J. Choi, N.D. Kim, J. Lee, B.P. Yu and H.Y. Chung (see also Laboratory Animals).
Keywords for this news article include: Texas, Genetics, San Antonio, United States, Laboratory Animals, North and Central America, Clinical Trials and Studies
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