Surviving Mesothelioma is reporting on new research at the
The researchers found that Vitamin C damaged the DNA of cancer cells, depleted levels of adenosine triphosphate (ATP) needed for energy, and inhibited the mammalian target of rapamycin (mTOR) pathway responsible for cancer cell proliferation and motility.
Just as importantly for people with mesothelioma and other cancers, when researchers gave intravenous Vitamin C along with conventional chemotherapy, it inhibited the growth of cancer cells in mice. Human patients who received the Vitamin C/chemotherapy combination experienced less toxicity from their treatments, a fact that could enable them to tolerate higher doses of cancer-killing drugs and more success.
The findings are similar to those of mesothelioma researchers in
In 2013, an Italian team found that a Vitamin C/antioxidant/chemotherapy combination had a synergistic effect on mesothelioma cells in the lab. In mice, it blocked both mesothelioma tumor growth and metastasis (spread). They proposed the combination as a new mesothelioma treatment.
The authors of the newest Vitamin C and cancer study agree. Writing in
The original research study appears in a recent issue of Science Translational Medicine. (Ma, Jan, et al, “High-Dose Parenteral Ascorbate Enhanced Chemosensitivity of Ovarian Cancer and Reduced Toxicity of Chemotherapy”,
For nearly ten years, Surviving Mesothelioma has brought readers the most important and ground-breaking news on the causes, diagnosis and treatment of mesothelioma. All Surviving Mesothelioma news is gathered and reported directly from the peer-reviewed medical literature. Written for patients and their loved ones, Surviving Mesothelioma news helps families make more informed decisions.
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