Daily News: Disease

Report Summarizes Nutrition and Food Research Study Findings from University of Leicester (The role of cancer stem cells in the anti-carcinogenicity...

Food Weekly News

08-28-14

Report Summarizes Nutrition and Food Research Study Findings from University of Leicester (The role of cancer stem cells in the anti-carcinogenicity of curcumin)

By a News Reporter-Staff News Editor at Food Weekly News -- Current study results on Nutrition and Food Research have been published. According to news reporting from Leicester, United Kingdom, by VerticalNews journalists, research stated, "Many cancers contain cell subpopulations that display characteristics of stem cells. These cells are characterised by their ability to self-renew, form differentiated progeny and develop resistance to chemotherapeutic strategies."

The news correspondents obtained a quote from the research from the University of Leicester, "Cancer stem cells may utilise many of the same signalling pathways as normal stem cells including Wnt, Notch and Hedgehog. The dietary agent curcumin exerts a plethora of anti-carcinogenic effects both in vitro and in vivo, and can also inhibit many of the signalling pathways associated with stem cell biology. Emerging evidence suggests that curcumin can exert its anti-carcinogenic activity via targeting cancer stem cells through the disruption of stem cell signalling pathways. In this review we summarise the ability of curcumin to interfere with signalling pathways Wnt, Hedgehog, Notch, Signal Transducers and Activator (STAT) and interleukin-8, and report curcumin-induced changes in function and properties of cancer stem cells."

According to the news reporters, the research concluded: "We present evidence that the effects of curcumin on cancer stem cells mediate, or contribute to, its anti-carcinogenic activity."

For more information on this research see: The role of cancer stem cells in the anti-carcinogenicity of curcumin. Molecular Nutrition & Food Research, 2013;57(9):1630-7. (Wiley-Blackwell - www.wiley.com/; Molecular Nutrition & Food Research - onlinelibrary.wiley.com/journal/10.1002/(ISSN)1613-4133)

Our news journalists report that additional information may be obtained by contacting L. Norris, Dept. of Cancer Studies and Molecular Medicine, University of Leicester, Leicester, UK. Additional authors for this research include A. Karmokar, L. Howells, W.P. Steward, A. Gescher and K. Brown.

Keywords for this news article include: Europe, Cancer, Oncology, Leicester, United Kingdom, Nutrition and Food Research.

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