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Folic acid (folate) is a member of the B-complex family. It is found in abundance in leafy green vegetables, but is often deficient in the standard American diet. Folic acid participates in a coenzyme reaction that synthesizes DNA needed for cell growth and new cell formation and helps convert vitamin B12 to one of its coenzyme forms.135-137

Folic acid provides the following health benefits:

• Helps protect chromosomes against genetic damage138*
• Helps prevent pregnancy complications such as birth defects, including neural tube defects, and certain heart defects and limb malformations
• Maintains already normal homocysteine levels which is important for heart health139-142*
• Participates in the utilization of sugar and amino acids carbohydrates143*
• Promotes healthier skin135*
• Helps maintain a healthy GI tract144*
• Maintains healthy endothelial function145*
• Improves mild memory problems associated with aging146*

A deficiency of folate can result in impaired cell division and protein synthesis. With diminished replacement of healthy red blood cells and intestinal cells, a decline in GI tract function can ensue. The systemic need for folate increases in certain states in which increased cell multiplication is needed. Chronic use of medications such as aspirin and antacids can interfere with the natural synthesis of folate.147

Healthful diets with adequate folate may reduce a woman’s risk of having a child with a brain or spinal cord defect. Women of childbearing age should consume 800 mcg of folate daily.*

Since folic acid can mask the most obvious effect of a vitamin B12 deficiency, Life Extension also offers folic acid capsules that contain vitamin B12. Those taking folic acid powder are advised to add vitamin B12 powder to their daily folic acid supplement.