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Dual-Action Cruciferous Vegetable Extract With Resveratrol & Cat's Claw
60 vegetarian capsules
Item Catalog Number: 00969 |
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Scientists have identified specific extracts from cruciferous vegetables (broccoli, cauliflower, Brussels sprouts, etc.) that modulate hormones in a way to help maintain healthy cell division. For instance, animal studies have shown that the cruciferous vegetable extract indole-3-carbinol (I3C) modulates estrogen hormones by favorably changing the ratio of protective 2-hydroxyestrone versus the damaging 16-hydroxyestrone.81 Indole-3-carbinol also induces phase I and II detoxifying enzymes that can help neutralize estrogen metabolites and xenobiotic estrogen-like environmental chemicals.82 Human studies support the beneficial role of I3C in positively altering estrogen metabolism.83 Di-indolyl-methane (DIM), a phytonutrient found in cruciferous vegetables, has been shown in animal studies to help maintain normal levels of a potentially damaging estrogen called 4-hydroxyestrone.85
I3C and DIM have been shown to affect the proliferation of cells containing DNA damage and induce DNA repair proteins. The glucosinolates are major constituents of cruciferous vegetables that have been shown to promote normal apoptosis and induce the expression of the beneficial p53 gene via an estrogen-independent action.86
Watercress contains isothiocyanates, but in a broader spectrum than does broccoli. The primary isothiocyanate precursor (PEITC) in watercress functions via four specific mechanisms to maintain healthy cell division.87 Extracts from rosemary enhance liver metabolism of estradiol and estrone,88 and help regulate the formation of DNA adducts,89 and have been shown to impede estrogen-induced growth promotion in certain tissues.88
Life Extension has combined its cruciferous vegetable complex with a standardized resveratrol extract based on indications from published scientific literature that resveratrol may also be an effective plant extract for maintaining optimal health. This organic whole-grape extract contains a spectrum of polyphenols naturally found in red wine, such as proanthocyanidins, anthocyanins, and flavonoids. |
| References |
| Supplement Facts |
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Serving Size 1 capsule |
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Servings Per Container 60 |
| Amount Per Serving |
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Broccoli (Brassica oleracea l.) Super Concentrate Extract (plant and sprouts) [std. to 4% glucosinolates (16 mg)] |
400 mg |
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Watercress (Nasturtium officinale) 4:1 Extract (leaf) |
100 mg |
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Indole-3-Carbinol (I3C) |
80 mg |
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Rosemary (Rosmarinus officinalis) Extract (leaves) [std. to 20% diterpenic compounds (10 mg) and providing carnosic acid/carnosol] |
50 mg |
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Cat's Claw (Uncaria tomentosa) Extract (bark) |
50 mg |
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Trans-resveratrol [also supplying glycosides (polydatin)] [from whole red grape (Vitis vinifera) and Polygonum cuspidatum (root) extract] |
20 mg |
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DIM (Di-indolyl-methane) |
14 mg |
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Other ingredients: rice flour, vegetable capsule, magnesium stearate, silica. |
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Contains corn and rice. This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree nuts, wheat, yeast, or gluten. Contains NO artificial sweeteners, flavors, colors, or preservatives. | |
| Dosage and Use |
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One capsule daily for individuals weighing up to 160 pounds. |
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Those weighing over 160 pounds, take two capsules daily. |
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This product can be taken with or without food, or as recommended by a healthcare practitioner. | |
| Caution |
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May interfere with oral contraceptives. If pregnant or intending to become pregnant, do not use this product. Do not use if taking antacids, H2-receptor blockers (e.g. Zantac®), or proton-pump inhibitors (e.g. Nexium®), as these drugs may impede the conversion of I3C to active metabolites. |
| Warnings |
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