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Tumor necrosis factor (TNF-alpha) is one such agent. These pro-inflammatory agents have been implicated in a host of age-related problems—among them health issues related to the joints.3
Along with these dangerous cytokines, imbalances of hormone-like messengers called prostaglandins also contribute to inflammatory
processes. Blocking these processes thus becomes crucial for joint health. Scientists have identified a number of natural agents that provide broad-spectrum support for healthy joint function and structure.
A step above joint supplements
ArthroMax™ with FruiteX B® is a step above most joint supplements by combining potent natural nutrients into one convenient formula to maintain healthy joints.*
Glucosamine is an aminopolysaccharide (a combination of an amino acid, glutamine, and a sugar, glucose). Glucosamine is concentrated in joint cartilage where it is incorporated in longer chains known as glycosaminoglycans and finally into very large structures known as proteoglycans. The proteoglycans function to attract water into the joint space for lubrication of the cartilage during movement. Glucosamine may also stimulate chondrocytes (cartilage cells) to begin producing healthy new cartilage matrix (both collagen and proteoglycans).33 In particular, N-acetyl glucosamine is the final form, which together with glucuronic acid, is polymerized to make the joint lubricant, hyaluronic acid.
Methylsulfonylmethane (MSM) is a metabolite of dimethylsulfoxide (DMSO), which has fluid-balancing properties.34 The role of MSM as a dietary supplement is as a sulfur donor. Sulfur is required for proper synthesis and maintenance of connective tissues such as skin, hair, nails, tendons, and cartilage.
Glucosamine provides the underlying structural foundation for joints,33 while methylsulfonylmethane (MSM) provides crucial sulfur compounds that are so important to maintain comfortable joint function.34,35 A clinical trial showed that a combination of glucosamine and MSM exerts better efficacy in reducing the joint discomfort and improving the functional ability of joints than the individual agents.36
A proprietary and patented natural citrus and palm fruit extract blend supplies standardized concentrations of citrus flavonoids, such as nobiletin and tangeritin with demonstrated potent effects in suppressing destructive cytokines such as tumor necrosis factor alpha (TNF-alpha) and interleukin-1 beta.37 In addition, nobiletin limits the production of joint-damaging prostaglandin E2.38 A special Boswellia extract known as 5-LOXIN® inhibits the 5-lipoxygenase enzyme, reducing levels of joint-damaging leukotriene B4.39
ArthroMax™ has been enhanced with FruiteX B® Osteo-Boron™, a patented form of boron that is chemically identical to the natural plant forms of boron found in food. Considered safer and more bioavailable than other forms of boron, FruiteX B® OsteoBoron™ not only supports strong bones but also healthy joints. Boron is a micronutrient that has been used historically in bone and joint supplements, possibly by down-regulating inflammation through the NF-kappaB pathway.
With this advanced combination of ingredients, ArthroMax™ with FruiteX B® is unique among joint supplements in its ability to provide the optimal nutrients to help maintain healthy joint structure and function. |