|Life Extension Update Exclusive |
Women who have fewer cardiovascular risk factors early in life live longer
In the October 6 2004 issue of the Journal of the American Medical Association, Martha L. Daviglus, MD, PhD, and her colleagues at Northwestern University in Chicago have found that young women who have favorable cardiovascular risk factors have a lower long-term death rate from coronary heart disease (CHD) and cardiovascular diseases (CVD), as well as all other causes compared to women with higher risk factor levels. Previous research had uncovered this phenomena in young and middle-aged men and in middle-aged women, but it had yet to be studied in younger women.
The study included participants in the Chicago Heart Association Detection Project in Industry which screened 39,522 men and women from 1967 to 1973 and ascertained deaths through 2001. The current study examined 7,302 female subjects who were between the ages of 18 to 39 and did not have coronary heart disease or electrocardiographic abnormalities upon enrollment. Twenty percent of the women were classified as being at low risk for coronary heart disease and cardiovascular disease, defined as having a favorable systolic and diastolic blood pressure and not taking blood pressure medications, having a serum cholesterol lower than 200 milligrams per deciliter and not being on cholesterol drugs, having a body mass index of less than 25, being a nondiabetic, and not smoking.
During the 31 year follow-up period, there were 469 deaths, with 47 from coronary heart disease and 94 caused by cardiovascular diseases. Women who had favorable levels of all five risk factors experienced much lower mortality from all causes compared to other women, and a rare incidence of coronary heart disease and cardiovascular disease. Those in the low risk category had less than 20 percent of the risk of cardiovascular disease mortality than those with more than two high risk factors, and their risk of all-cause mortality during the follow-up period was less than half.
The results of the study emphasize the benefit of adopting early measures to extend the length and quality of life. The authors write: "Our findings show that for young women, a low cardiovascular risk profile is associated with lower long-term CHD, CVD, and all-cause mortality--results in concert with previous findings on young men and middle-aged men and women. They demonstrate that among persons at low risk earlier in life, CHD and CVD cease to occur at epidemic rates. These data underscore the importance of a national public priority emphasizing prevention and control of all major CVD risk factors by lifestyle approaches from conception, weaning, childhood, and youth on to increase proportions of the population at low CVD risk."
Cardiovascular disease: Comprehensive analysis
You can take each of the nutrients recommended in this protocol separately if you choose to. This will involve spending a lot of time and money. Most people find it more convenient to take specially designed formulas that provide most of the recommended cardiovascular-protecting nutrients. Here is a brief description of six formulas that provide optimal potencies of most of the nutrients described in this protocol:
Life Extension Mix
This formula contains 89 different ingredients including the following nutrients that have been shown to benefit cardiovascular health:
- Vitamin A
- Vitamin C
- Vitamin E
- Vitamin B1
- Vitamin B6
- Vitamin B12
- Vitamin D
- Vitamin E (alpha-tocopherol)
- Folic acid
Super Life Extension Booster
This softgel oil capsule provides many important nutrients, including the following that have been shown beneficial in protecting cardiovascular health:
- Vitamin K
- Ginkgo biloba extract
- Gamma tocopherol
- Folic acid
- Vitamin B12
These capsules contain potent anti-aging nutrients, including the following that have demonstrated benefit in preventing and treating cardiovascular disease:
- Alpha lipoic acid
Provides optimal potencies of essential fatty acids from fish oil (DHA and EPA) plus a potent dose of GLA from borage oil.
Provides high potency coenzyme Q10 in an emulsified oil base along with added tocotrienols.
Super GLA/DHA capsules
Fatty acids are essential for life. Besides storing energy, these fats are part of our makeup; they live in our healthy cells, muscles, nerves, and organs. Conversely, there are bad fats that must be controlled or avoided to maintain good health.
Supplementation with the right proportions of fatty acids can maximize the production of anti-inflammatory prostaglandins (E1 and E3), while suppressing proinflammatory prostaglandin E2 and leukotriene B4. In addition to avoiding saturated fats and high glycemic foods that contribute to chronic inflammation, eating omega-3 foods, and consuming supplements that provide GLA and DHA can help control inflammation by bringing balance to the essential fatty acids.
Super CoQ10 with Tocotrienols and Quercetin
CoQ10 is an essential component of the respiratory cycle of the cell that takes place in the mitochondria and generates ATP, the cell’s energy currency.
Orally administered CoQ10 goes directly to the mitochondria where it works to regulate the oxidation of fats and sugars into energy—an important function since the natural production of CoQ10 declines with advancing age. When the body has an ample amount of CoQ10 the mitochondria can work most efficiently throughout the entire body, in cells everywhere, including the most densely populated area, the heart.
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