Aging results in an increase of inflammatory cytokines (destructive cell-signaling chemicals) that contribute to the progression of many degenerative diseases (Van der Meide et al. 1996; Licinio et al. 1999). Rheumatoid arthritis is a classic autoimmune disorder in which excess levels of cytokines such as tumor necrosis factor-alpha (TNF-a), interleukin-6 (IL-6), interleukin 1b [IL-1(b)], and/or interleukin-8 (IL-8) are known to cause or contribute to the inflammatory syndrome (Deon et al. 2001).
Chronic inflammation is also involved in diseases as diverse as atherosclerosis, cancer, heart valve dysfunction, obesity, diabetes, congestive heart failure, digestive system diseases, and Alzheimer's disease (Brouqui et al. 1994; Devaux et al. 1997; De Keyser et al. 1998).
Scientists have identified dietary supplements and prescription drugs that can reduce levels of the pro-inflammatory cytokines. The docosahexaenoic acid (DHA) fraction of fish oil is the best documented supplement to suppress TNF-a, IL-6, IL-1(b), and IL-8 (Jeyarajah et al. 1999; James et al. 2000; Watanabe et al. 2000; Yano et al. 2000). A study on healthy humans and those with rheumatoid disease shows that fish oil suppresses these dangerous cytokines by up to 90% (James et al. 2000).
Other cytokine-lowering supplements are DHEA (Casson et al. 1993), vitamin K (Reddi et al. 1995; Weber 1997), GLA (gamma linolenic acid) (Purasiri et al. 1994), and nettle leaf extract (Teucher et al. 1996). Antioxidants, such as vitamin E (Devaraj et al. 2000) and N-acetyl-cysteine (Gosset et al. 1999), may also lower pro-inflammatory cytokines and protect against their toxic effects.
Life Extension Vacations
Second Annual Life Extension Cruise
Our first cruise was so successful that we decided to offer another one in 2008! Attendees told us they were able to learn a lot about the latest in integrative therapies and antiaging research and at the same time have plenty of fun aboard the cruise ship.
This time we will cruise the splendor of the Alaskan wilderness aboard Celebrity’s sumptuous Infinity. You’ll enjoy our Life Extension seminars, one-on-one consultations, a welcome aboard cocktail reception, exceptional personal service, award-winning cuisine, world-famous amenities, accommodations that are the most spacious at sea, and much more.
The second Life Extension Seminar at Sea will be a 7-night cruise on August 29, 2008.
Special features for Life Extension Members:
- Celebrity Concierge Class (191 sq ft) – from $1,973 per person
- Floor-to-ceiling glass doors
- Large sitting area
- Enhanced service
- Priority embarkation/disembarkation
- Fresh fruit and flowers
- Welcome champagne
- Hansgrohe massaging showerhead
Book by January 31, 2008, and receive an exceptional value coupon book with $200 in onboard savings!
For reservations or for more information please call Life Extension Vacations at 800-791-4457 or email firstname.lastname@example.org.
We are looking forward to seeing you onboard!